The water channel aquaporin-5 (AQP5) is essential in transepithelial water transport in secretory glands. AQP5 is ectopically overexpressed in breast cancer, where expression is associated with lymph node metastasis and poor prognosis. Besides the role in water transport, AQP5 has been found to play a role in cancer metastasis, migration, and proliferation. AQP5 has also been shown to be involved

The emergence of COVID-19 has been changing in the world since 2020 and prompted social, cultural, and economic systems to adjust their structures, routines, and processes. The economic aspects of the pandemic appeared soon, and many industries changed their workflow and procedures through a mandatory or recommended quarantine. Knowing the impact of COVID-19 on different areas of construction proj

Near-field earthquake is one of the primary sources of ground motions that significantly affecting the structure's seismic response in its surrounding area containing pulse-long periods. The two popular and reliable approaches for the seismic investigation of structures are known as the force and displacement-based seismic design (FBD and DBD), extensively developed in the literature. In the prese

Urbanization growth and aging infrastructures necessitate new infrastructure construction projects in congested urban areas. Urban construction projects interrupt the regular on-road vehicle traffic flow that affects air pollution concentration in the adjacent areas. The project schedule, however, is a possible contributor to the air pollution which has been neglected to date. This research propos

The high vehicle congestion is the main contributing factor to air pollution originated from the engine's combustion in many urban areas. Grade separation projects have been used to solve this problem and have resulted in overall air pollution reduction in many cases. Many grade separation projects are constructed near sensitive urban locations accommodating susceptible individuals. This research

This thesis is mainly concerned with investigations of approximation problems on spaces of analytic functions on the unit disc in the complex plane, which naturally arise in connection to spectral problems of certain classes of linear operators acting on the spaces in question. For instance, quasi-nilpotency of certain analytic paraproducts on the Hardy spaces and on the Bergman spaces are investi

BACKGROUND AND OBJECTIVES: Curative treatment for locally advanced head and neck tumours often includes reconstructive surgery using a microvascular free flap. Effective recuperation is essential but may be impeded by postoperative donor site pain. The aim of this study was to evaluate the effects of a continuous popliteal block on postoperative pain after fibular graft harvesting.MATERIAL AND MET

Vertically aligned metal halide perovskite (MHP) nanowires are promising for various optoelectronic applications, which can be further enhanced by heterostructures. However, present methods to obtain free-standing vertically aligned MHP nanowire arrays and heterostructures lack the scalability needed for applications. We use a low-temperature solution process to prepare free-standing vertically al

Microbial stoichiometry has become a key aspect in ecological research as shifts in microbial C:N, C:P and N:P ratios upon nutrient addition are presumed to give insight into relative nutrient limitations for soil microorganisms–with far-reaching implications for biogeochemical processes. However, this expectation has never been tested against direct methods of microbial growth responses to nutrie

Two patterns of bacterial growth response upon drying and rewetting (DRW) of soils have previously been identified. Bacterial growth can either start increasing immediately after rewetting in a linear fashion (“type 1” response) or start increasing exponentially after a lag period (“type 2” response). The effect of repeated DRW cycles was studied in three soils with different response patterns aft

Anthropogenic warming is expected to accelerate global soil organic carbon (SOC) losses via microbial decomposition, yet, there is still no consensus on the loss magnitude. In this Perspective, we argue that, despite the mechanistic uncertainty underlying these losses, there is confidence that a strong, positive land carbon–climate feedback can be expected. Two major lines of evidence support net

How can an online course be designed to promote better mood and improved lighting and darkness conditions in the home? Based on the Information-Motivation-Behaviour Skills Model, the online course comprises multiple components (light, activity and sleep) and various learning strategies. Factual information is provided about, e.g. light as the most potent external time cue for the internal body cloHow can an online course be designed to promote better mood and improved lighting and darkness conditions in the home? Based on the Information-Motivation-Behaviour Skills Model, the online course comprises multiple components (light, activity and sleep) and various learning strategies. Factual information is provided about, e.g. light as the most potent external time cue for the internal body clo

Road safety policy rules us in both visible and invisible ways and prioritising one mode often means downgrading another. It has been argued in previous research that road safety policy prioritises car traffic and in that way sustains the automobility norm. This paper focuses on the automobility norm that permeates Swedish road safety policy and how this hampers planning for cycling. It aims to co

Background: Substance use among older persons occurs with medical and psychiatric comorbidities. This study examined the associations of substance use disorder (SUD), psychiatric, and dual diagnoses with 12-month cumulative hospitalized days, hospital admission rate and number of days to first hospitalization.Methods: The cohort of 3,624 individuals (28.2% women) aged 50 years or older was assesse

Between 1980 and 2000, a number of Sub-Saharan African countries entered into conditional structural adjustment lending arrangements with the International Monetary Fund (IMF) in response to economic crisis and decline. Despite the fact that the crises had been due in part to long-term overdependence on primary sector activities, such as cash crop agriculture and natural resource extraction, many

Concerns have been raised over the quality of evidence on the performance of medical artificial intelligence devices, including devices that are already on the market in the USA and Europe. Recently, the Medical Device Regulation, which aims to set high standards of safety and quality, has become applicable in the European Union. The aim of this article is to discuss whether, and how, the Medical