In the radioimmunotherapy of malignancies the uptake of monoclonal antibodies (MoAb) is commonly low in tumors compared with normal tissue. Several methods have been suggested to increase the tumor-to-normal tissue (T/N) ratio. In this study we have investigated the biodistribution of different amounts of 125I-L6-biotin MoAb in combination with a preload of unlabeled L6 MoAb. Nude rats were inject

The alkali metal emission from materials collected in a PFB biomass gasification pilot plant has been characterized. Samples of SiC filter ash and fluidized bed particles from different operating conditions were subjected to a constant heating rate up to 1000 degrees C in a nitrogen atmosphere, and the alkali metal emission was monitored continuously by a surface ionization technique. For all samp

The utility of the PCR-based AFLP technique (polymerase chain reactions amplified fragment length polymorphisms) was explored in elucidating details of polyploid evolution in the Eurasian orchid genus Dactylorhiza. We emphasized Swedish taxa but also included some material from the British Isles and elsewhere in Europe. Three different sets of primers, amplifying different subsets of restriction f

Protein G-related alpha(2)-macroglobulin-binding (GRAB) protein is a cell wall-attached determinant of group A streptococcus (GAS) that interacts with the human protease inhibitor a 2-macroglobulin (alpha(2)-M). Of 86 clinical isolates tested, 23% could bind a alpha(2)-M. However, all strains tested contained the grab gene. High levels of anti-GRAB antibodies were found in the serum of convalescen

Introduction: Risedronate, a bisphosphonate for treatment and prevention of osteoporosis, has been shown in several clinical trials to reduce the risk of fractures in postmenopausal women with osteoporosis. The cost-effectiveness of risedronate treatment has previously been evaluated within different country settings using different model and analysis approaches. The objective of this study was to

Polychlorinated biphenyls (PCBs) and organic pesticides (i.e., DDTs) were measured in long finned eels (Anguilla dieffenbachii) in 17 streams on the west coast of South Island, New Zealand. Very low levels of PCBs and low levels of ppDDE were found. The concentrations of PCBs and ppDDE were not correlated within sites indicating that different processes determined the levels of the two pollutants

Pre-treatment of sludge before anaerobic digestion can increase methane production and degradation of organic matter. There are various pre-treatment methods for this purpose. Anaerobic digestion tests were performed for comparison of three pre-treatment methods (hygienisation, ultrasonic treatment and enzyme dosing) used separately or in combination on biosludge and mixed sludge. COD solubilisati

We compare the generation and decay dynamics of charges and excitons in a model polymer semiconductor (MEH-PPV) in solution and drop-cast thin films, by recording the sub-ps transient complex conductivity using THz time-domain spectroscopy. The results show that the quantum efficiency of charge generation is two orders of magnitude smaller in solution (~10–5) than in the solid film (~10–3). The pr

Excited states in the N=Z+1 nucleus Kr-73 have been investigated using the Ca-40(Ar-36,2pn) and Ca-40(Ca-40,alpha2pn) reactions at 145 and 160 MeV, respectively. gamma rays were detected using the Gammasphere array and events were recorded in coincidence with charged-particle and neutron detectors. The three previously observed bands were extended to high spin, and a new unfavored positive-parity

Popular Abstract in Swedish Kartering av primärproduktion i Västrafrikanska Sahel genom användning av satellitdata. I avhandlingen har utvecklats en Light Use Efficency (LUE) modell som medger kartering av bruttoprimärproduktionen (GPP) exemplifierad i ett område i Västafrikanska Sahel. Modellen utnyttjar satellitbaserad månatlig Normalised Difference Vegetation Index (NDVI) tillsammans med andraA light Use Efficiency (LUE) model is developed that allows the mapping of total growing season Gross Primary Production (GPP) for the West African Sahel, using the Normalized Difference Vegetation Index (NDVI) together with other data. Image quality may be poor in monthly NDVI maximum value composites as shown by an improved geostatistical noise estimation technique. Quality may be improved by ot

Dissociation of 6He on a lead target has been studied at 240 MeV/u. The four-momenta of the two neutrons in coincidence with greek small letter alpha-particles have been measured and used to reconstruct the three-body energy and angular correlations in the final state. For the first time, three-body correlations were included in the analysis of the 6He dissociation data, and compared with calculat

Regulation of the telomerase catalytic subunit, hTERT, is a complex process accomplished on many levels. Transcription of the hTERT gene has been widely studied but less is known about the implication of genetic variations. Recently, a functional T to C transition polymorphisin was indicated 1327 bp upstream the hTERT transcription starting site. The C-1327/C genotype was associated with shorter t

Popular Abstract in Swedish Parallellt med att kommunerna under 1990-talet fick ett utvidgat ansvar för t.ex. vården av och omsorgen om äldre och funktionshindrade gavs de större frihet att lokalt bestämma över sina organisationsformer. Omständigheterna ledde till ett starkt kommunalt reformtryck, inte minst genom de reformförslag som på olika sätt och i varierande grad utmanade den traditionella The 1990s was a period characterized by a strong pressure for reform in the Swedish municipalities. The care manager reform, i.e. the initiation of a position within the administration - the care manager - whose work tasks are concentrated around needs-assessment practices only, was one of many reform proposals. Within a fairly short time span a great number of municipalities decided to implement

Infants treated in neonatal intensive care units suffer an increased risk for invasive candidiasis, but the diagnosis is sometimes difficult. D-arabinitol is a metabolite of most pathogenic Candida species. An elevated urine D-arabinitol/L-arabinitol (DA/LA) ratio is a sensitive sign of invasive candidiasis in children with cancer, but the method has not been previously evaluated for newborn infan

OBJECTIVE: To evaluate clinical usefulness of cerebrospinal fluid stroke volume (SV) assessed in the cerebral aqueduct, via cine phase-contrast magnetic resonance imaging, for predicting outcome after shunt surgery in suspected normal pressure hydrocephalus. METHODS: Thirty-eight patients with suspected normal pressure hydrocephalus were included. SV was assessed using cine phase-contrast magnetic