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Interactions between genetic predisposition to obesity, insulin resistance and type 2 diabetes risk, and food or beverage intake for incident type 2 diabetes : European Prospective Investigation into Cancer and Nutrition (EPIC) InterAct case–cohort study

Background: Limited evidence exists for effect modification of genetic characteristics on the associations of food consumption and incident type 2 diabetes (T2D). Objectives: We aimed to investigate whether the food-T2D association would vary by genetic susceptibility to metabolic traits. Methods: We analyzed data from 9542 incident T2D cases and a subcohort of 12,477 participants nested within th

Between Admiration and Resistance: Postcolonial Legacies and Indonesian Public Perceptions of the European Union

Relations between the European Union (EU) and Indonesia have expanded significantly in recent decades, yet public perceptions of the EU in Indonesia are shaped not only by contemporary policies but also by enduring postcolonial legacies. In postcolonial societies, global actors are often interpreted through historically grounded narratives that influence how authority, legitimacy, and partnership

Factors affecting reproduction of Snow Leopards (Panthera uncia) in captivity: age, experience, and contraception

As snow leopards (Panthera uncia) are vulnerable in the wild, individuals in captivity function as a backup for the wild population. However, space limitations make it difficult to keep the captive population healthy. To maintain high genetic diversity in the captive population, it is important to carefully consider breeding recommendations and the use of contraception. This study examined age-rel

Identification and functional characterization of novel genes involved in the Cellulase-Induced Resistance to Alamethicin (CIRA) pathway in Arabidopsis thaliana

Trichoderma are fungi that form symbiotic relationships with plant roots, representing an ecological topic for pest management. It offers a sustainable alternative to agrochemicals through biostimulation and biocontrol. However, the host plant needs to effectively manage a trade-off : using Trichoderma as a defense mechanism while not getting damaged by its cytotoxic compounds, like the antibiotic

Nästa generation av tumörbehandling? : Kap. IV. Pre-Kirurgisk Intermittent Strålbehandling och immunoadjuvant hypertermi

Sammanfattning av Kapitel IV:Detta kapitel handlar om att kombinera Pre-kirurgisk strålbehandling och hypertermi (värmebehandling) med fokus på immunologiska effekter. Hypertermi (HT ca 41–44 °C) gör tumörceller mer känsliga för strålning (RT). Kliniska studier visar bättre respons och fler kompletta remissioner med kombinationen RT+HT jämfört med enbart strålning (RT) utan att öka allvarliga bive

Early glymphatic failure in AppNL-F knock-in mice is linked to parenchymal border macrophages loss

Amyloid-β (Aβ) accumulation is a hallmark of Alzheimer’s disease. Cerebral Aβ deposition is attenuated by a functional glymphatic system, in which perivascular entry of cerebrospinal fluid (CSF) and its exchange with interstitial fluid mediate solute clearance. Parenchymal border macrophages (PBMs), positioned along glymphatic pathways, are emerging as important players for glymphatic clearance. H

Digital Vulnerabilities

Maria Arnelid, Petter Falk, Desirée Enlund, ErickaJohnson, Sara Mörtsell, Olof Sundin, Fredrik StiernstedtRecent global events, including the COVID-19 pandemic, wars and migration streams, have highlighted the promise of digital infrastructures while also showcasing how dependent we are on digital systems for accessing welfare services such as healthcare, social services and education, as well as for accessing public service media. Notably, in the context of welfare provision, different people and soc

From Eyes to Icons : The Visual Poetics of the Empty Tomb in Greek Gospel Narratives

In the New Testament gospel accounts of the empty tomb, there is a strong emphasis on vision and sight. This emphasis is at times understood as a reference to the role of eyewitnesses and their testimonies in the formation of the gospel tradition. This study, however, reads the visual elements of the texts as part of their poetics, as part of their narrative and rhetorical setting.By looking at ei

Health-based nanomaterial guidance value (HNGV) for occupational exposure to spheroidal biodurable engineered nanomaterials of relatively low substance-specific toxicity

Exposure to engineered nanomaterials (ENMs) at the workplace can adversely affect human health via inhalation. Occupational exposure limits (OELs) for specific ENMs remain scarce due to a lack of nano-specific data and consensus on the most appropriate dose metric for exposure assessment. In 2022, recommendations were provided on how to derive Health-based Nano Reference Values (HNRVs) for differe

Unplanned intensive care unit admission after elective colon cancer resection : population-based registry study

Background: The incidence, aetiology, and outcome of unplanned intensive care unit admission after elective colon cancer surgery remain unclear. This study investigated the incidence of, and factors associated with, unplanned intensive care unit admission following elective colon cancer resection in Sweden. Methods: This nationwide retrospective registry study included adult patients undergoing el

Frånluftsvärmepump eller FTX-ventilation i ett äldre flerbostadshus med självdrag - En analys av energianvändning, inneklimat och kostnader

The average build year for existing multi-family buildings in Sweden is1959, circa 95 % of building built before 1960 uses natural ventilation and circa 45 % of these have failed the obligatory ventilation control that exists in Sweden. In the EU buildings stand for 30 % of the total energy usage and the aim is to get buildings to a near zero energy building. The aim of this thesis is therefore to