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We introduce MEGATRON, a new galaxy formation model for cosmological radiation hydrodynamics simulations of high-redshift galaxies. The model accounts for the non-equilibrium chemistry and heating/cooling processes of ≥ 80 atoms, ions, and molecules, coupled to on-the-fly radiation transfer. We apply the model in a cosmological setting to the formation of a 109 M⊙halo at z = 6, and run 25 realizat

This study examined whether Growth Differentiation Factor-15 (GDF-15) and echocardiographic measures of systolic left ventricular function improve intermediate- and long-term mortality risk prediction beyond the guideline-endorsed GRACE 2.0 score after Acute Coronary Syndrome (ACS). 751 ACS patients were included. GDF-15, left ventricular ejection fraction (LVEF), and global longitudinal strain (G

Preconception health status, especially of women, but also of men, is known to influence pregnancy outcomes. Despite knowledge of the growing importance of preconception health, numerous challenges remain for conducting research in this population and delivering appropriate clinical care. The 2023 Global Pregnancy Collaboration annual workshop focused on exploring preconception health as it relate

The growing challenge of antibiotic resistance calls for alternative therapeutic strategies beyond conventional antibiotics. Antibacterial Photodynamic Therapy (aPDT), based on the light-induced generation of Reactive Oxygen Species (ROS), offers a non-specific approach that is detrimental to bacterial cells at multiple levels. Here, we explore the photocatalytic properties of nitrogen-doped titan

This thesis examines why forward integration into hospitality remains a selective rather than widespread strategy in the alcohol industry. While strategic theory suggests that owning the point of consumption can strengthen brand control and reduce coordination risk, most alcohol producers continue to rely on third-party venues. This study explores why that gap exists. Drawing on transaction cost e

Inom matematisk statistik behandlas vanligtvis problemet att med hjälp av begränsad information uppskatta händelser av olika slag. I generell mening behöver informationen inte nödvändigtvis vara tal, utan kan exempelvis vara observationer av formen på en elektrisk våg eller av himlakroppars konfiguration. En vanlig gemensam egenskap hos informationen är emellertid att den härstammar från de matemaLévy processes are the left-invariant cadlag Markov processes on a Lie group or homogeneous space. This thesis deals with compound processes, the Lévy processes obtained as random walks whose walking frequency is driven by a homogeneous Poisson process. Methods of decompounding, i.e. the problem of inferring the step distribution of a compound process, will be established and analyzed. It will be

In this thesis, we investigate the water-wave problem for two-dimensional steady waves with constant vorticity. We introduce a new approximate model that, in its simplest form, reduces to a planar dynamical system. We then analyze this system for various energy levels and vorticity constants, studying its phase portraits to determine the locations and types of solutions that arise. In the unidire

Oats (Avena sativa L.) are gaining increased attention for their rich dietary fibres, proteins and bioactive compounds. Among fibres, starch components denoted as resistant starch (RS) contribute significantly to the functional and nutritional properties of oat-based foods. This study presents the optimization of a high-throughput quantification method for amylose, a key structural component that

Urbanisation, digitalisation and emerging technologies are reshaping young people’s relationship with the outdoor environment. We investigate how everyday outdoor experiences and spaces support adolescent wellbeing, understood as both feeling good and functioning well. Adolescents, at a pivotal stage in life, are particularly sensitive to environmental factors that influence their wellbeing. We co

This dissertation studies the critical reception of Hilma af Klint trough three exhibitions: Spiritual in Art – Abstract Painting 1890-1985 (Los Angeles, 1986), Secret Pictures by Hilma af Klint, (Helsinki, 1988) and Hilma af Klint – A Pioneer of Abstraction (Stockholm, 2013), addressing the crucial prominent figures and voices in the discursive field around af Klint. The aim is carried out throug

The remains of a wooden stronghold and a fortified manor have been found in Hedemora and Husby parishes in southern Dalecarlia, along with a late medieval city and the northernmost monastery in Sweden. They all stem from the period between about 1350 and 1500. These buildings are the focus of this thesis, which attempts to explore why the architectural expressions from this era are found in these

Bricklaying is one of the most accident-prone professions in the construction industry, with heavy and non-ergonomic lifting being a leading cause of sick leave and back problems. Increased automation is expected to reduce the number of work-related accidents while simultaneously improving productivity. Existing solutions are often expensive and inflexible. This thesis investigates how a pick- and

Sammanfattning Den här studien undersöker tekniska lösningar för bräddmätning inom VA SYDs ledningsnät, med fokus på att förbättra driftssäkerheten vid kritiska bräddpunkter. Genom fältstudier, intervjuer och litteratur har olika sensorteknologier analyserats, där bland annat Siemens SITRANS LR120 har visat sig särskilt lovande. Projektet behandlar hur korrekt konfiguration, kommunikationsval och

Hur kan materialåtgången minskas utan att försämra hållfastheten i betongstrukturer? Det är en tämligen svår fråga men svaret kanske kan hittas med hjälp av spänningsbegränsad strukturoptimering och förspänd betong. Betong är ett av samhällets mest använda byggmaterial och utgör grunden i hus, broar och annan infrastruktur. Materialets stora styrka är dess förmåga att bära trycklaster. När betongConcrete exhibits high compressive strength but limited tensile strength, which restricts its applications where it's structurally efficient with respect to cost, manufacturability and strength. Prestressing is commonly used to counteract tensile stress by introducing compressive forces but the combination of prestressed concrete and optimization is still under development. An important aspect

Chronic obstructive pulmonary disease (COPD) and asthma are heterogeneous respiratory diseases with overlapping symptoms but distinct underlying biology. As both diseases involve dysregulated inflammatory signalling, identifying disease- and compartment-specific pathways and biomarkers could improve diagnosis and treatment. A disintegrin and metalloproteinase 17 (ADAM17) is a key sheddase that inf

Hexavalent chromium (Cr(VI)) is classified as a Group 1 human carcinogen and increases the risk of lung cancer because it can generate reactive oxygen species, induce DNA damage, and trigger epigenetic alterations Occupational Cr(VI) exposure can occur during different work processes, but when this PhD study was initiated, the exposure level to Cr(VI) at Swedish workplaces and its health risk were