3He MRI-based Assessment of Posture-dependent Regional Ventilation Gradients in Rats.
A recently developed method for quantitative assessment of regional lung ventilation was employed for the study of posture-dependent ventilation differences in rats. The measurement employed hyperpolarized 3He MRI to detect the build-up of the signal intensity after increasing numbers of 3He breaths, which allowed for computation of a regional ventilation parameter. A group of six anesthetized rat
