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Musik för klimatet

Syftet med hemsidan är att presentera vetenskapliga artiklar inom miljö- och hållbarhetsforskning genom ett samspel mellan musik och text. Vi hoppas på detta sätt att kunna tillgängliggöra dessa fakta och frågeställningar för en bredare publik. På ett okonventionellt och nyskapande vis, genom att kombinera musik och illustrationer/recitation, vill vi föra ut budskapet om, och öka intresset för, hu

Severe infections in patients with ANCA-associated vasculitis treated with rituximab

Objectives: Rituximab (RTX) is an anti-CD20 antibody that selectively depletes B cells and has emerged as a therapy for ANCA-associated vasculitis (AAV) during the past decade. This study sought to quantify and determine potential risk factors for severe infections in AAV patients treated with RTX at rheumatology clinics in Mexico City, Mexico and Lund, Sweden. Methods: The study consisted of a re

Legality and legitimacy in international law

This chapter explores how diffent approaches to the concept of legitimacy are reflected in the different understandings of law endorsed by legal positivism, legal idealism and legal realism.

Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3

Frontotemporal dementia type 3 (FTD3), caused by a point mutation in the charged multivesicular body protein 2B (CHMP2B), affects mitochondrial ultrastructure and the endolysosomal pathway in neurons. To dissect the astrocyte-specific impact of mutant CHMP2B expression, we generated astrocytes from human induced pluripotent stem cells (hiPSCs) and confirmed our findings in CHMP2B mutant mice. Our

Search for long-lived particles in final states with displaced dimuon vertices in pp collisions at s =13 TeV with the ATLAS detector

A search is performed for a long-lived particle decaying into a final state that includes a pair of muons of opposite-sign electric charge, using proton-proton collision data collected at s=13 TeV by the ATLAS detector at the Large Hadron Collider corresponding to an integrated luminosity of 32.9 fb-1. No significant excess over the Standard Model expectation is observed. Limits at 95% confidence

CSF Aβ42 and Aβ40 and their relation to brain soluble and insoluble Aβ in the 5xFAD mouse model of Alzheimer's disease

BACKGROUND: In patients with AD, CSF Aβ42 is reduced while Aβ40 remains unchanged. It has been suggested that altered CSF Aβ42 is due to aggregation of this peptide into insoluble plaques, resulting in less soluble Aβ42 available for secretion to the CSF. However, the relations between soluble and insoluble Aβ42 and Aβ40 in the brain and the concentrations of these Aβ peptides in CSF are not well

Search for Heavy Higgs Bosons Decaying into Two Tau Leptons with the ATLAS Detector Using pp Collisions at s =13 TeV

A search for heavy neutral Higgs bosons is performed using the LHC Run 2 data, corresponding to an integrated luminosity of 139 fb-1 of proton-proton collisions at s=13 TeV recorded with the ATLAS detector. The search for heavy resonances is performed over the mass range 0.2-2.5 TeV for the τ+τ-decay with at least one τ-lepton decaying into final states with hadrons. The data are in good agreement

Search for heavy neutral Higgs bosons produced in association with b-quarks and decaying into b-quarks at s =13 TeV with the ATLAS detector

A search for heavy neutral Higgs bosons produced in association with one or two b-quarks and decaying to b-quark pairs is presented using 27.8 fb-1 of s=13 TeV proton-proton collision data recorded by the ATLAS detector at the Large Hadron Collider during 2015 and 2016. No evidence of a signal is found. Upper limits on the heavy neutral Higgs boson production cross section times its branching rati

COVID-19-related loneliness and social isolation in caregivers of people with brain health challenges : The CLIC-Caregiver Global Survey

BACKGROUND: Prior to COVID-19, >90% of caregivers of people with brain health challenges (dementia, mental ill health, intellectual disability) experienced high levels of distress, burden, loneliness and social isolation. The COVID-19 pandemic has significantly increased these impacts, particularly since these caregivers are often older and physically vulnerable themselves. The aim of this cross-s

Associations between the APOE-ε2 and APOE-ε4 alleles with resistance and resilience against Alzheimer's disease pathology

BACKGROUND: To examine associations between the APOE-ε2 and APOE-ε4 alleles and core Alzheimer's disease (AD) pathological hallmarks as measured by amyloid-β (Aβ) and tau PET in older individuals without dementia. METHOD: We analyzed data from 462 ADNI participants without dementia who underwent Aβ ([18 F]florbetapir or [18 F]florbetaben) and tau ([18 F]flortaucipir) PET, structural MRI and cognit

Measurement of the tt¯ production cross-section and lepton differential distributions in eμ dilepton events from pp collisions at √s=13TeV with the ATLAS detector

The inclusive top quark pair (tt¯) production cross-section σtt¯ has been measured in proton–proton collisions at s=13TeV, using 36.1 fb- 1 of data collected in 2015–2016 by the ATLAS experiment at the LHC. Using events with an opposite-charge eμ pair and b-tagged jets, the cross-section is measured to be: σtt¯=826.4±3.6(stat)±11.5(syst)±15.7(lumi)±1.9(beam)pb,where the uncertainties reflect the l

Experimental Model of Pulmonary Inflammation Induced by SARS-CoV-2 Spike Protein and Endotoxin

COVID-19 is characterized by a dysregulated and excessive inflammatory response and, in severe cases, acute respiratory distress syndrome. We have recently demonstrated a previously unknown high-affinity interaction between the SARS-CoV-2 spike (S) protein and bacterial lipopolysaccharide (LPS), leading to the boosting of inflammation. Here we present a mouse inflammation model employing the coadm

The multiple meanings of the gender-inclusive pronoun hen : Predicting attitudes and use

The Swedish gender-inclusive pronoun hen can be used generically (referring to anyone), or specifically (referring to non-binary gender identities). Three studies tested evaluations and use of hen, and individual-level predictors. In Study 1 (N = 2145), specific hen was slightly favoured over generic hen. In Study 2 (N = 297), hen was more negatively evaluated than binary pronouns, and generic hen

Search for chargino-neutralino production with mass splittings near the electroweak scale in three-lepton final states in s =13 TeV pp collisions with the ATLAS detector

A search for supersymmetry through the pair production of electroweakinos with mass splittings near the electroweak scale and decaying via on-shell W and Z bosons is presented for a three-lepton final state. The analyzed proton-proton collision data taken at a center-of-mass energy of s=13 TeV were collected between 2015 and 2018 by the ATLAS experiment at the Large Hadron Collider, corresponding

Controlling Body Sources of Noise Generated by Niddle Electrogram Machines : A New EMG Idea for Skipping Traditional Approaches

Different signal frequencies from body tissues, muscles fat etc affects the EMG signals. The signal frequencies from body organ can considered as noise which affects the output and hence for better signal output noised should be minimised. Traditional EMG machines supports analogue filtering while residual noises carried by signal channels. For good and better signal aggregation and useful data ga

Nedstängningarna står inte på vetenskaplig grund

Nedstängningar har liten smittskyddseffekt och stora ekonomiska och sociala kostnader. Pandemilagen står inte på stabil vetenskaplig grund utan är ett oroväckande tecken på vad som rimligen bör diagnostiseras som pandemipopulism, skriver Fredrik NG Andersson och Lars Jonung vid Ekonomihögskolan i Lund.

Teacher interventions and student strategies for circular motion problems : A matrix representation

Students' understanding of forces in circular motion is often incomplete. The problems are not limited to confusions about centripetal acceleration and centrifugal forces. This paper considers possible effects of different interventions by a teacher who has discovered the many types of free-body diagrams drawn by students for circular motion in a vertical plane. Students' free-body diagrams often