Time-course of liver fat accumulation in man after a single load of ethanol
Three healthy young male subjects were given a single load of ethanol (approximately 3 g/kg body weight) over 5 hours. Liver aspiration biopsies were performed at the start of the experiment and 6, 14, 24, and 48 hours after the start. Blood alcohol and serum transaminase activity levels were measured simultaneously. Triglycerides and phospholipids of the liver biopsy material were determined by a