Popular Abstract in Swedish Lymfom är en grupp tumörsjukdomar som uppkommer från de vita blodkropparna i vårt immunförsvar. Diffust storcelligt B-cellslymfom (DLBCL) är en av de mest aggressiva varianterna av lymfom och uppkommer från den typen av vita blodkroppar som kallas B-celler. Varje år drabbas ca 500 personer i Sverige av DLBCL. Typiska symtom är hastigt tillväxande lymfkörtlar samt viktneDiffuse large B-cell lymphoma (DLBCL) is an aggressive and heterogeneous disease. Identification of prognostic and predictive markers is important to design individualised and effective treatment strategies. This thesis describes different approaches to search for molecular prognostic markers and an attempt to overcome chemotherapy resistance in DLBCL. In the first study it was investigated whet

Expression of fibroblast growth factor-8 (FGF-8) is increased in a large number of breast cancers. In in vitro and in vivo breast cancer models FGF-8 promotes growth, invasion and angiogenesis. In the present work we have studied the mechanisms by which FGF-8b and its receptors (FGFR1-3) promote breast cancer cell growth using S115 murine and human MCF-7 breast cancer cell lines in in vitro and i

The growing complexity of industrial robot work-cells calls for the use of advanced orchestration techniques to promote flexibility and reusability. This paper presents a solution based on service-oriented platforms that endorses the separation of concerns, coordination and execution. The execution is kept inside each individual device and their functionality is exposed via automatic generation of

Background: Principles of brain plasticity is used in the treatment of patients with functional limitations to improve sensorimotor function. Training is included in the treatment of knee injury to improve both patient-reported function and sensorimotor function. However, impairment in sensorimotor function often persists despite training. Therefore, it was suggested that training programs need to

Background: Published associations between dietary carotenoids and vitamin C and bladder cancer risk are inconsistent. Biomarkers may provide more accurate measures of nutrient status. Objective: We investigated the association between plasma carotenoids and vitamin C and risk of urothelial cell carcinoma (UCC) in a case-control study nested within the European Prospective Investigation into Cance

Viruses can be described as biological objects composed mainly of two parts: a stiff protein shell called a capsid, and a core inside the capsid containing the nucleic acid and liquid. In many double-stranded DNA bacterial viruses (aka phage), the volume ratio between the liquid and the encapsidated DNA is approximately 1:1. Due to the dominant DNA hydration force, water strongly mediates the inte

Anthropogenic acidification has reduced soil pH and released potentially toxic aluminium (Al) ions in many regions. This investigation examines whether increased acidity has caused genetic adaptation to acidic conditions within the grass species Elymus caninus, Poa nemoralis, Deschampsia cespitosa and D. flexuosa. We sampled tussocks (genets) of each species in two regions of southern Sweden, diff

This paper is based on a new procedure for dynamic output feedback design for systems with nonlinearities satisfying quadratic constraints. The new procedure is motivated by the challenges of output feedback control design for the 3-state Moore-Greitzer compressor model. First, we use conditions for stability of a transformed system and the associated matching conditions to find the data of the st

In autobiographical writing, the mirror is not only a privileged metaphor for the genre as a whole; it also functions as a primary administrator of boundaries, demarcating the space of the self from the foreign, the chaotic, the unknown. The mirror metaphor is not a gender neutral one: in Western elite culture the mirror has served to reinforce the patriarchal dichotomy between man/mind and woman/

Background: Previous research has focused exclusively on weight loss or weight maintenance following weight loss, i.e. secondary weight maintenance (SWM). The long-term results of SWM have been modest, suggesting that preventing initial weight gain among normal weight or overweight individuals, i.e. primary weight maintenance (PWM), may be more successful. The aim of this study was to compare the

Purpose – Although the significance of the learning organization concept is recognised in innovation management, there are only a few studies on the way in which a learning orientation affects new service development (NSD) in the hotel industry in Iran. This paper aims to fill that gap. Design/methodology/approach – A questionnaire is designed to ask hotel managers and owners for their thoughts o

Today, innovation is a key word for many universities, as it constitutes an important part of most universities’ public and scientific outreach task. Many universities are striving to increase the number of innovations generated at the university. A common method is to provide various support for research projects e.g.; providing researchers with information about international patent rights (IPR)

Feedback is an ancient idea, but feedback control is a young field. Nature long ago discovered feedback since it is essential for homeostasis and life. It was the key for harnessing power in the industrial revolution and is today found everywhere around us. Its development as a field involved contributions from engineers, mathematicians, economists and physicists. It is the first systems disciplin

The aim of the project was to explore and describe the views of physiotherapy students concerning sexual health as a part of physiotherapy education, and to enable them in their future profession as physiotherapists to be able to discuss sexual health matters with patients in an informed, sensitive and relaxed way. A qualitative interview study with data collection through focus group interviews w