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Human prostate is now considered a target for vitamin D receptor (VDR) ligands, such as BXL-628. Because BXL-628 inhibited prostate growth without interfering with androgen signaling, it represents a new option for benign prostate hyperplasia (BPH) therapy. However, BPH symptoms are related not only to prostate size, but also to compensatory bladder hypertrophy and eventual overactivity. We now re
Sex-allocation trade-offs have long been invoked as a primary factor underlying the evolution of separate sexes and the reduction of pollen production accompanying the evolution of selfing. In the present study, I conducted stamen and style removal experiments to explore the existence of such trade-offs in Nigella sativa, a hermaphroditic plant species whose flower structure allows early manipulat
The acyl-coenzyme A-binding proteins (ACBPs) contain 26 highly conserved sequence positions. The majority of these have been mutated in the bovine protein, and their influence on the rate of two-state folding and unfolding has been measured. The results identify eight sequence positions, out of 24 probed, that are critical for fast productive folding. The residues are all hydrophobic and located i
Popular Abstract in Swedish Denna avhandling behandlar olika aspekter av den svenska föräldraförsäkringen. Avhandlingen inleds med ett översiktligt kapitel i vilket föräldraförsäkringens historia samt nyttjandet av föräldraförsäkringen under perioden 1993-2005 beskrivs. Därefter följer två studier som behandlar tillfällig föräldraledighet (för vård av sjukt barn) och en studie som behandlar föräldThis thesis contains an introductory chapter and three essays, all considering different aspects of the Swedish parental insurance. In the first two essays, different aspects of temporary parental leave (leave from work to take care of a sick child) are investigated, whereas the third essay considers parental leave (leave from work to take care of a new-born child). In the first essay, On the Sha
Canon and oblivion. The memorials of archaeology The Sun-Chariot from Trundholm is world famous, and the finding place is marked with a monument. In the same way the finding places for The golden horns from Gallehus, the Egtved girl, the Dejbjerg chariots, the Gundestrup cauldron, the Nydam boat and many other finds have been remembered during the 20th Century with memorials, often a stone monum
BACKGROUND: The epidemiology of hepatitis C virus (HCV) infection has been studied in many countries. However, little is known about HCV infection in Lithuania, a Baltic country, that was part of the former Soviet Union. OBJECTIVES: The aim of this study was to determine and evaluate the etiology of acute viral hepatitis, the risk factors for acquiring HCV in comparison to hepatitis B virus (HBV),
Groundwater discharge areas in boreal forest ecosystems can potentially be areas where Fe and Al accumulate in the forest floor and affect the solubility of P. This study was conducted to determine phosphate sorption properties using humus soils containing high native amounts of Al and Fe. Humus soils were collected from two different forested groundwater discharge areas varying in pH and amount a
Voluntary agreements represent a policy instrument for applying new knowledge, routines or technology to specified issues. The traditional role of an authority when using information, and taking economic, or administrative measures is that of an initiator and controller. Voluntary agreements, on the other hand, represent a communication process between an authority and a partner where relations of
Artikel om statyresande och identitetsfrågor kring Öresund från sent 1800-tal till sent 1900-tal.
Atomism is defined as the view that the moral value of any object is ultimately determined by simple features whose contribution to the value of an object is always the same, independently of context. A morally fundamental feature, in a given context, is defined as one whose contribution in that context is determined by no other value fact. Three theses are defended, which together entail atomism:
The effect of noradrenaline (NA) on mucociliary activity in the rabbit maxillary sinus was investigated in vivo by injecting it at increasing dosages (10(-11) to 10(-4) mol/kg) into the maxillary artery, the mucociliary response being recorded photoelectrically. NA increased mucociliary activity at a dosage of 10(-5) mol/kg, the maximal increase being 16.1 +/- 2.6%. The NA-induced stimulation of m
Över två generationer har Indien och Kina förändrats från slumrande jättar med stora problem till snabbt uppvaknande kontinenter med långtgående anspråk på en plats i världspolitiken och den globala ekonomin. Deras snabbt skiftande situation har naturligtvis förändrat våra bilder dramatiskt och med dem vad vi tror oss veta om utvecklingens drivkrafter i den moderna världen. Frågan är dock om vi ve
Moderate hyperhomocysteinemia, an independent cardiovascular risk factor, has been reported in renal transplant recipients. In the present study, plasma concentrations of total homocysteine were significantly increased in 120 renal transplant recipients as compared with 60 healthy controls (19.0 +/- 6.9 vs. 11.6 +/- 2.8 mumol/L, P < 0.0001) and as compared with 53 patients without a transplant but
In laser-assisted combustion diagnostics it is a recurring task to predict molecular transitions whose signal strength depends only weakly on variations in temperature. The signal strength is proportional to the Boltzmann fraction of the level probed and the amplitude of the absorption line profile. In the past investigations have been presented in which this task was attack by detailed numerical
Useful clinical tests are lacking for the controversial entity "cervical vertigo". In earlier studies patients assumed to suffer from cervical vertigo or dizziness manifested disturbed postural control as compared to healthy subjects, but were hard to distinguish from patients with other balance disorders. Using posturography in which stance was perturbed by a vibratory stimulus applied towards th
