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SNPS in FGF5 and ZNF652 show parent-of-origin specific effects on blood pressure in families from the Botnia study
Pediatric coeliac disease
CHEK2 1100delC in patients with metachronous cancers of the breast and the colorectum
Modeling of Pulverised Wood Flames
The aim of the current work was at development and validation of modeling tools for simulation of pulverised wood flames in furnaces and study how different factors influence on such flames. The numerical model involves different sub-models for the physo-chemical processes, such as, two-phase flow motion, drying, devolatilization and shrinkage of particles, the formation and oxidation of volatile,
Gestational Islet Autoimmunity, Infections, and Type 1 Diabetes
The intention of this thesis was to investigate autoimmune markers for type 1 diabetes, together with signs of enterovirus infections during the pre- and perinatal period of life, and their possible association with the development of diabetes during childhood, adolescence, and young adulthood. We found that: 1. Newborns with ABO immunization, linked in epidemiological studies with heightened diab
Neurogenesis in the adult brain from ballyhoo to sobriety
New neurons are spontaneously generated in two regions of the adult brain, the hippocampus and the subventricular zone/olfactory bulb. The objective of this thesis was to study potential implications for adult neurogenesis in Alzheimer's (AD) and Parkinson's diseases (PD). PD is characterized by degeneration of dopaminergic neurons in the substantia nigra. It has been suggested that new dopaminer
Breaking the boundaries of careers. A study of the mobility effects of a program for career councelling
Rekommendationer från Svenska kvalitetskommittén för karotiskirurgi. Ultraljud bra preoperativ metod för gradering av karotisstenos
The estimated degree of carotid stenosis is decisive for the selection of patients who would benefit from surgical treatment. Carotid thrombendarterectomy is recommended in patients with symptomatic > or = 80 procent internal carotid artery stenosis (ECST method). Many vascular centers now often rely entirely on duplex ultrasonography to select the patients for carotid surgery. The results of a re
Orthostatic Hypotension Predicts Long-Term Incidence Of Heart Failure
Vascular smooth muscle mechanotransduction and plasticity-the role of microRNA, calcium signaling and actin polymerization
Smooth muscle cells residing in the blood vessel media are constantly exposed to mechanical forces exerted by the intraluminal pressure. The smooth muscle senses and adapts to mechanical forces by activation of multiple signaling pathways and cytoskeletal rearrangements. Stretch of the vascular wall is therefore an important factor that controls smooth muscle cell phenotype and function. The goal
Kartläggning av skyddsfaktorer vid typ 1-diabetes har börjat. Vissa patienter tycks skyddade mot sena komplikationer--flera studier pågår.
Ökad betydelse av svensk grundlag för att skydda grundläggande rättigheter i arbetslivet?
Use of Phosphodiesterase 5 Inhibitors Associates With Risk of Colorectal Cancer in Men With Benign Colorectal Neoplasms
BACKGROUND & AIMS: Phosphodiesterase 5 (PDE5) inhibitors have been proposed to have chemopreventative effects on colorectal cancer (CRC), although data are needed from population-based studies. We performed a nationwide cohort study to investigate the association between use of PDE5 inhibitors and risk of CRC in men with benign colorectal neoplasms.METHODS: We identified men who received a dia
Tillämplig lag avseende utomobligatoriskt ansvar för kollektiva stridsåtgärder på arbetsmarknaden
Något om avtalsstatutets roll för fastställande av uppfyllelseort enligt Bryssel 1a-förordningens artikel 7(1)(b)
Low Testosterone, but Not Estradiol, Is Associated With Incident Falls in Older Men : The International MrOS Study
Fracture risk is determined by bone strength and the risk of falls. The relationship between serum sex steroids and bone strength parameters in men is well known, whereas the predictive value of sex steroids for falls is less studied. The aim of this study was to assess the associations between serum testosterone (T) and estradiol (E2) and the likelihood of falls. Older men (aged ≥65 years) from t
