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Evaluation of the production of exopolysaccharides by two strains of the thermophilic bacterium Rhodothermus marinus

The thermophile Rhodothermus marinus produces extracellular polysaccharides (EPSs) that forms a distinct cellular capsule. Here, the first data on EPS production in strains DSM4252(T) and MAT493 are reported and compared. Cultures of both strains, supplemented with either glucose, sucrose, lactose or maltose showed that the EPS were produced both in the exponential and stationary growth phase and

Baddeleyite U–Pb ages and gechemistry of the 1875–1835 Ma Black Hills Dyke Swarm across north-eastern South Africa : part of a trans-Kalahari Craton back-arc setting?

Eleven new baddeleyite U–Pb crystallisation ages and associated whole-rock geochemistry on NE–NNE-trending tholeiitic dykes cutting across the north-eastern corner of the Archaean Kaapvaal Craton, the overlying Transvaal basin and the Bushveld and Phalaborwa igneous complexes collectively define a 1875–1835 Ma Black Hills Dyke Swarm (BHDS). Dyke ages do not discriminate between dyke trends or geog

Patient-reported long-term outcome after primary hypospadias repair

Purpose: Long-term evaluation of the surgical outcome after puberty, particularly patient reported outcome is rare in the literature. The aims of this study were to investigation the patients' satisfaction with the long-term results and their views and memories of their childhood surgery and follow-up. Methods: A modified version of previously used questionnaire was sent to 134 patients ages 18 ye

New U–Pb age and paleomagnetic constraints from the Uitkomst Complex, South Africa : clues to the timing of intrusion

The Uitkomst Complex is considered to be coeval with, and genetically linked to the Rustenburg Layered Suite (RLS) of the Bushveld Large Igneous Province. This study reports new paleomagnetic, geochemical and geochronological results from the Uitkomst Complex and a crosscutting dyke at the Nkomati Mine. Primary magnetisations for the complex and the dyke are statistically indistinguishable. This,

Visual complications in patients with biopsy-proven giant cell arteritis : A population-based study

Objective. To study the clinical and laboratory characteristics of patients with biopsy-proven giant cell arteritis (GCA) with visual complications, and to evaluate the incidence rate of visual complications in GCA compared to the background population. Methods. Data from 840 patients with GCA in the county of Skane, Sweden, diagnosed between 1997 and 2010, were used for this analysis. Cases with

Venous thromboembolism and cancer risk

Cancer increases the risk of venous thromboembolism (VTE) and about 20 % of all VTE are associated with cancer. VTE can also be used as a marker for occult cancer. The objective was to examine the correlation between VTE and cancer regarding predictors for a subsequent cancer diagnosis. Patients treated for VTE between January 1st 2006 and December 31th 2011 were extracted from the Swedish nationa

Inhibition of phosphodiesterase 3, 4, and 5 induces endolymphatic hydrops in mouse inner ear, as evaluated with repeated 9.4T MRI

Conclusion: The data indicate important roles for phosphodiesterase (PDE) 3, 4, 5, and related cAMP and cGMP pools in the regulation of inner ear fluid homeostasis. Thus, dysfunction of these enzymes might contribute to pathologies of the inner ear. Objective: The mechanisms underlying endolymphatic hydrops, a hallmark of inner ear dysfunction, are not known in detail; however, altered balance in

Identification of discrepancies in grain quality and grain protein composition through avenin proteins of oat after an effort to increase protein content

Background: Oat prolamin (avenin) is a family of proteins that contain several polymorphic components. The highinterspecific variability of avenin among cultivars, electrophoretic patterns have been used for grain protein comparisonand species relationships. Therefore, the present study was carried out to evaluate the effect of environment onavenin constitution following an effort to increase prot

Development of High-Protein Oat for the Feed and Food Industry

Oats are an excellent source of high-quality proteins, with a favourable amino acid composition. Oat proteins therefore have greatpotential to complement existing animal and plant protein sources, especially if the protein content could be increased. In this thesis,high-protein oat lines were identified and characterised. More than a thousand individual lines in a mutagenised oat population(Target

Antennal and behavioural responses of the spruce seedmoth, Cydia strobilella, to floral volatiles of Norwayspruce, Picea abies, and temporal variation in emissionof active compounds

We investigated whether spruce seed moth, Cydia strobilella L. (Lepidoptera: Tortricidae, Grapholitini), one of the most damaging seed predators on Norway spruce, Picea abies (L.) H. Karst (Pinaceae), uses olfactory cues during host search. Analyses with coupled gas chromatography and electroantennography revealed that antennae of both sexes of moths responded consistently to three compounds in th

Validation of data quality in the Swedish National Register for Oesophageal and Gastric Cancer

Background: The Swedish National Register for Oesophageal and Gastric Cancer (NREV) was launched in 2006. Data are reported at diagnosis (diagnostic survey), at the time of surgery (surgical survey) and at first outpatient follow-up (follow-up survey). The aim of this study was to evaluate data originating from NREV in terms of comparability, completeness, accuracy and timeliness. Methods: Coding

Metastatic spread in patients with gastric cancer

Background: The epidemiology of metastatic gastric cancer is unexplored because cancer registries seldom cover metastatic involvement apart from "present or not". We used a novel approach by utilizing Swedish registers to assess metastatic spread in gastric cancer. To our knowledge, this is the first nationwide description of metastases in gastric cancer. Results: The most common sites of metastas

5-HT2B receptor antagonists attenuate myofibroblast differentiation and subsequent fibrotic responses in vitro and in vivo

Pulmonary fibrosis is characterized by excessive accumulation of connective tissue, along with activated extracellular matrix (ECM)-producing cells, myofibroblasts. The pathological mechanisms are not well known, however serotonin (5-HT) and 5-HT class 2 (5-HT2) receptors have been associated with fibrosis. The aim of the present study was to investigate the role of 5-HT2B receptors in fibrosis, u

Infection-related and -unrelated malignancies, HIV and the aging population

Objectives: HIV-positive people have increased risk of infection-related malignancies (IRMs) and infection-unrelated malignancies (IURMs). The aim of the study was to determine the impact of aging on future IRM and IURM incidence. Methods: People enrolled in EuroSIDA and followed from the latest of the first visit or 1 January 2001 until the last visit or death were included in the study. Poisson

Shared genetic factors involved in celiac disease, type 2 diabetes and anorexia nervosa suggest common molecular pathways for chronic diseases

Background and Objectives: Genome-wide association studies (GWAS) have identified several genetic regions involved in immune-regulatory mechanisms to be associated with celiac disease. Previous GWAS also revealed an over-representation of genes involved in type 2 diabetes and anorexia nervosa associated with celiac disease, suggesting involvement of common metabolic pathways for development of the

A Bivariate Genetic Analysis of Drug Abuse Ascertained Through Medical and Criminal Registries in Swedish Twins, Siblings and Half-Siblings

Using Swedish nationwide registry data, the authors investigated the correlation of genetic and environmental risk factors in the etiology of drug abuse as ascertained from medical and criminal registries by modeling twin and sibling data. Medical drug abuse was defined using public inpatient and outpatient records, while criminal drug abuse was ascertained through legal records. Twin, full and ha

Age-related differences in the sonographic characteristics of endometriomas

Study Question Do sonographic characteristics of ovarian endometriomas vary with age in premenopausal women? Summary Answer With increasing age, multilocular cysts and cysts with papillations and other solid components become more common whereas ground glass echogenicity of cyst fluid becomes less common. What is Known Already Expectant or medical management of women with endometriomas is now acce