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Lack of ST2 aggravates glioma invasiveness, vascular abnormality, and immune suppression

Background. Glioblastoma (GBM) is the most common primary malignant brain tumor in adults, characterized by aggressive growth and a dismal prognosis. Interleukin-33 (IL-33) and its receptor ST2 have emerged as regulators of glioma growth, but their exact function in tumorigenesis has not been deciphered. Indeed, previous studies on IL-33 in cancer have yielded somewhat opposing results as to wheth

Comparative safety and efficacy of new-generation single-layer polytetrafluorethylene- versus polyurethane-covered stents in patients with coronary artery perforation for the RECOVER (REsults after percutaneous interventions with COVERed stents) Investigators

New-generation single-layer polytetrafluorethylene (PTFE-) or polyurethane (PU-) covered stent (CS) for the treatment of coronary artery perforation (CAP) during PCI offer high procedural efficacy. To evaluate the comparative long-term safety and efficacy of both devices. This is a multicenter pooled analysis of individual data of patients with CAP undergoing implantation of single-layer PTFE-CS o

The Impact of Witnessing School Bullying in the Classroom : Exploring Perceptions and Responses Among Turkish Students

This study addresses the impact of witnessing different types of school bullying on Turkish school students who are bystanders. The primary aim is to investigate how the type of bullying (direct/indirect; ostracism/devaluation) affects the perception of bullying and the roles witnesses take. Additionally, we explore whether gender, global state self-esteem, and identification with one’s school acc

Proportion of acceptable symptom state nearly tripled with improvements in patient-reported outcomes for all symptom state subgroups : A registry study of over 15,000 osteoarthritis patients in a digital education and exercise therapy

OBJECTIVE: This study investigated trajectories of patient acceptable symptom state (PASS) among participants of a digital education and exercise therapy for knee and hip osteoarthritis.METHODS: A longitudinal observational study among individuals aged 40+ years who participated in the digital program. Participants completed PASS (yes/no) at enrolment and at least one follow-up during one year aft

Grassroots innovations in agriculture innovation systems : insights into seabuckthorn (Hippophae rhamnoides) in Ladakh, India

Purpose: Agriculture innovation systems (AIS) examine the complex socio-technical and institutional aspects affecting sustainable agriculture. However, it is predominantly constrained to the formal sector activities in the high-income countries (HICs). The informal sector actors play a major role in the agricultural sector of low- and middle-income countries (LMICs), such as India, by innovating a

Heavy and super-heavy nuclei and elements : production and properties: Editorial preface to the topical collection

The advances in understanding and producing heavy and super-heavy elements is the subject of this topical collection. The main covered subjects are: the description of the theory, developments of super-heavies and the determination of the Island of Stability as well as the role of these nuclei as part of the r-process scenario. The accurate determination of reaction processes are crucial to enable

Stadsliv utan stadsbuss? En studie om busstrafikens påverkan på handel i Lunds stadskärna

2024 godkände Lunds kommun en ny strategi för utveckling av Lunds stadskärna. I strategin läggs ett anmärkningsvärt förslag fram: att ta bort de vanliga stadsbussarna från stadskärnan, och ersätta dem med lokala minibussar. Små stadskärnebussar är i sig inget nytt koncept, men fungerar vanligen som ett komplement till den ordinarie kollektivtrafiken; inte som en ersättning. Studier av jämförbara lIn 2024, Lund municipality approved a new strategic document about enhancing the city centre of Lund. In this document, a questionable suggestion is put forth: to replace the buses serving the city centre with minibuses. City centre minibuses is not an entirely new concept; however, it is conventionally used as a complement to ordinary buses rather than as a replacement. Studies on similar measure

Lärande även för lärare! – Förutsättningar för organisatoriskt lärande i teknisk utbildning

Engineering Education faces increasing demands to improve the quality of teaching and learning. At the same time, universities are described as slow-moving institutions and evaluations highlight recuring challenges. A key prerequisite for change is learning. This thesis aims to investigate the relationship between organisational learning and teachers’ decisions regarding course development in engi

Rituals and Counter-Rituals: The Role of Ritual in Gamifying War and Undermining Oppression in the Hunger Games Trilogy

This thesis examines how rituals gamify war in the Hunger Games trilogy. Using a formalist lens, I argue that ritual is a rhythmic, repetitive, and looped form found in both media and real-world conflicts. By comparing the forms within the novel to those in video games and war, I explore the ethical dangers of associating war with game, while also revealing the subversive potential of ritual. The

Det ofullständiga subjektet - Monstret, maskinerna och den posthumana etiken

Denna uppsats undersöker hur Mary Shelleys Frankenstein och Philip K. Dicks Do Androids Dream of Electric Sheep? kan problematisera den humanistiska etikens ideal. Genom en komparativ analys av hur romanerna gestaltar hybrida varelser utforskas frågor om moraliskt ansvar, subjektivt erkännande och etiska normer. Analysens fokus ligger vid hur dessa båda verk skildrar det icke-mänskliga subjektets

Modeling of Fiber bond fracture using X-FEM and Element Removal

The aim of this thesis is to investigate the mechanical response of paperboard in the out-of-plane direction by incorporating its microstructural characteristics, with a particular focus on fiber-fiber interactions and fracture mechanisms. These features are implemented into models of varying complexity to evaluate their influence on material behavior. Two fracture modeling techniques, the Extend

Det lesbiska ’jaget’ i översättning. Lesbiskt subjektskapande och översättande skrivande utifrån Violette Leducs La Bâtarde och Eva Alexandersons översättning Oäktingen samt roman Kontradans

Inom de översättnings- och litteraturvetenskapliga fälten i Sverige saknas en tolkningstradition som tar hänsyn till översatta texters särskilda villkor samtidigt som de inkluderar dessa som en del av författaröversättares totala litterära produktion. Syftet med denna studie är därför att visa hur en analys som tar det översättande skrivandet i beaktning möjliggör en fördjupad förståelse av det li

Det finns en (...) som inte kan översättas - Tystnad som text, känsla, tid och rum i Tolk

Föreliggande uppsats undersöker hur tystnad gestaltas i Maja Lee Langvads Tolk (2024). Genom att gå i dialog med Mara Lees avhandling i litterär gestaltning När Andra skriver: skrivande som motstånd, ansvar och tid (2014) belyses hur tystnaden i Lee Langvads roman kan förstås som något rumsligt, relationellt och tidsligt. Från Lees avhandling hämtas begrepp som Andra, temporalitet och förskjutning