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EuroHeart: European Unified Registries On Heart Care Evaluation and Randomized Trials.

Major advances in cardiovascular medicine have been driven by innovations in basic research in biological and technical sciences. The subsequent testing in prospective randomized controlled trials (RCT) has provided the evidence underpinning the introduction of new, more effective, and safer treatments. New publication in European Heart Journal

https://www.lupop.lu.se/article/euroheart-european-unified-registries-heart-care-evaluation-and-randomized-trials - 2025-12-18

National poisoning registers and toxicovigilance in different countries as models for Germany

As of 2019, Germany has still not been able to provide a national poisoning register and toxicovigilance for sufficient and reliable information on human exposure for the purpose of identification and assessment of toxic risk to the public. In particular, the USA acts as a special model, but France, the Netherlands, Switzerland, and Sweden also have efficient poisoning registers and toxicovigilanc

https://www.lupop.lu.se/article/national-poisoning-registers-and-toxicovigilance-different-countries-models-germany - 2025-12-18

Prediction of Lymph Node Metastasis in Breast Cancer by Gene Expression and Clinicopathological Models: Development and Validation within a Population-Based Cohort

More than 70% of patients with breast cancer present with node-negative disease, yet all undergo surgical axillary staging. We aimed to define predictors of nodal metastasis using clinicopathological characteristics (CLINICAL), gene expression data (GEX), and mixed features (MIXED) and to identify patients at low risk of metastasis who might be spared sentinel lymph node biopsy (SLNB). New publica

https://www.lupop.lu.se/article/prediction-lymph-node-metastasis-breast-cancer-gene-expression-and-clinicopathological-models - 2025-12-18

Echocardiographic Findings in Patients with Mild to Moderate Chronic Kidney Disease without Symptomatic Heart Failure

A significant association between mild to moderate impairment of renal function and echocardiographic markers of cardiac structure and diastolic function was observed, supporting the hypothesis that interaction between the kidney and heart exists even in the early stages of renal impairment. Read the full paper here.

https://www.lupop.lu.se/article/echocardiographic-findings-patients-mild-moderate-chronic-kidney-disease-without-symptomatic-heart - 2025-12-18

Demographic and diagnostic profiles of older people with intellectual disability and prescription of antipsychotics

Older people with ID may be prescribed antipsychotic medication without thorough psychiatric diagnosing. Thus, there is a need for improving the abilities of health care professionals to properly diagnose and manage psychiatric illness in this population. Read the full paper here.

https://www.lupop.lu.se/article/demographic-and-diagnostic-profiles-older-people-intellectual-disability-and-prescription - 2025-12-18

Using a Web-Based Data Collection Platform to Implement an Effective Electronic Patient-Reported Outcome Registry

Routine patient-reported outcome measure (PROM) collection often disrupts clinical workflow and can place a burden on both the patient and the provider. Electronic PROM collection systems, if implemented deliberately to maximize convenience and efficiency, have the potential to mitigate these obstacles. Read the full paper here.

https://www.lupop.lu.se/article/using-web-based-data-collection-platform-implement-effective-electronic-patient-reported-outcome - 2025-12-18