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The SCHOLAR-2 retrospective study highlighted poor overall survival (OS) with standard of care (SOC) regimens among patients with relapsed/refractory (R/R) mantle cell lymphoma (MCL) who failed a covalent Bruton tyrosine kinase inhibitor (BTKi). In the ZUMA-2 single-arm trial, brexucabtagene autoleucel (brexu-cel; autologous anti-CD19 CAR T-cell therapy) demonstrated high rates of durable response

INTRODUCTION: We examined whether sex modifies the association between APOE ε2 and cognitive decline in two independent samples. METHODS: We used observational data from cognitively unimpaired non-Hispanic White (NHW) and non-Hispanic Black (NHB) adults. Linear mixed models examined interactive associations of APOE genotype (ε2 or ε4 carrier vs. ε3/ε3) and sex on cognitive decline in NHW and NHB p

Scenarios are a useful tool to help think about and visualise the future and, as such, are utilised by many policymakers and practitioners. Future scenarios have not been used to explore the urban context in much depth, yet have the potential to provide valuable insights into the robustness of decisions being made today in the name of sustainability. As part of a major research project entitled Ur

In type 2 diabetes (T2D), hepatic insulin resistance is strongly associated with nonalcoholic fatty liver disease (NAFLD). In this study, we hypothesized that the DNA methylome of livers from patients with T2D compared with livers of individuals with normal plasma glucose levels can unveil some mechanism of hepatic insulin resistance that could link to NAFLD. Using DNA methylome and transcriptome

We investigated seven children from six families to expand the phenotypic spectrum associated with an early infantile epileptic encephalopathy caused by biallelic pathogenic variants in the phosphatidylinositol glycan anchor biosynthesis class Q (PIGQ) gene. The affected children were all identified by clinical or research exome sequencing. Clinical data, including EEGs and MRIs, was comprehensive

Accurate diagnosis of rare inherited anaemias is challenging, requiring a series of complex and expensive laboratory tests. Targeted next-generation-sequencing (NGS) has been used to investigate these disorders, but the selection of genes on individual panels has been narrow and the validation strategies used have fallen short of the standards required for clinical use. Clinical-grade validation o

Mantle cell lymphoma (MCL) after relapse is associated with poor prognosis. No standard of care exists and available evidence for treatments is limited, particularly in patients who fail Bruton tyrosine kinase inhibitor (BTKi) therapy. This multicentre retrospective chart review study, SCHOLAR-2, addresses this knowledge gap and reports on data collected from 240 patients with relapsed/refractory

OBJECTIVE: In a multicenter cohort of probable dementia with Lewy bodies (DLB), we tested the hypothesis that β-amyloid and tau biomarker positivity increases with age, which is modified by APOE genotype and sex, and that there are isolated and synergistic associations with the clinical phenotype. METHODS: We included 417 patients with DLB (age 45-93 years, 31% women). Positivity on β-amyloid (A+)

Allm studieplan hälsovet 2017 Postadress Box 117, 221 00 LUND Telefon växel 046-222 00 00 Telefax 046-222 41 70 E-post info@med.lu.se Internet http://www.med.lu.se Medic inska faku l te tss tyre lsen Allmän studieplan för utbildning på forskarnivå inom det hälsovetenskapliga området - arbetsterapi, omvårdnad, fysioterapi http://www.med.lu.se/utbildning/forskarutbildning (Fastställd av Medicinska f

https://www.intramed.lu.se/sites/intramed.lu.se/files/2022-12/allman-studieplan-halsovetenskaper-2017-01-01.pdf - 2025-12-28

1 Frank Heller SVINDLARE, KOSMOPOLIT, FÖRFATTARE UTSTÄLLNING PÅ UNIVERSITETSBIBLIOTEKET I LUND FEBRUARI – JUNI 2022 2 3 Dr Serner och Mr Heller Gunnar Serner var under pseudonymen Frank Heller Sveriges mest framgångsrike underhållningsförfattare under 1900-talets första hälft. Sammanlagt skrev han fler än femtio böcker, de allra flesta i äventyrs- genren. Han blev mest känd för böckerna om den små

https://www.ub.lu.se/sites/ub.lu.se/files/2022-02/utstallningskatalog-frank-heller.pdf - 2025-12-28

Fraud and other offences, aimed towards the financial interestets of the union, are seriously harming the union’s budget every year. To guarantee a better protection of the unions finances, the Commission put forward Pro-posal for a Council Regulation on the establishment of the European Public Prosecutor’s Office . The Office will have an exclusive competence to in-vestigate and prosecute crimina

Ekonomin i Kina har blomstrat över de senaste tiotal åren, och tillsammans med det skyhöga antalet invånare, strävar landet nu efter att uppnå världens största medelklass. Men för att Kina och hela världen skall kunna upprätthålla en levnadsstandard likt den vi har i väst, så kommer vi göra det på stor bekostnad av klimatet. Huvudsakligen sker det på grund av den massiva förbränning av kol och fosMeteorological conditions are influenced everyday by air-bound aerosols and pollution in the atmosphere, and understanding these processes from micro to synoptic scale, is essential for forecasting and creating high resolution weather models. In this study, three different experimental weather models are analysed to provide some understanding on how various meteorological parameters are influenced

In July 2023, the Swedish government appointed an inquiry with the purpose of conducting a comprehensive review of the penalty scales and presenting proposals for a reformed and fairer penalty system. The government empha- sizes in the directive that the penal system should express a clearer condem- nation of the blameworthiness of criminal acts in order to avoid that victims experience the legal

I ljuset av BEPS-projektets strävan efter effektivare tvistlösningsförfaranden i samband med dubbelbeskattning har EU tagit fram mekanismer som avser att effektivisera skattetvistlösning inom unionen. Resultatet blev rådets direktiv (EU) 2017/1852 av den 10 oktober 2017 om skattetvistlösnings-mekanismer i Europeiska unionen (skattetvistlösningsdirektivet), vilket sedan 2019 även är implementerat iIn the light of the BEPS projects aim to implement more effective dispute resolution mechanisms in situations where a double taxation may occur the EU have worked to develop mechanisms to make dispute resolution within the union more effective. The EU’s effort resulted in the Council Directive (EU) 2017/1852 of 10 October 2017 on Tax Dispute Resolution Mechanisms in the European Union (the Tax Dis

När Lissabonfördraget trädde i kraft den 1 december 2009 medförde det viktiga förändringar inom EU:s utrikespolitik. Målet var att öka EU:s samstämmighet i dess externa relationer i syfte att stärka EU:s roll som global aktör. Det nya fördraget inrättade en hög representant för den gemensamma utrikes-och säkerhetspolitiken (HR) samt en assisterande utrikestjänst (EEAS). De nya funktionerna är histThe entry into force of the Lisbon Treaty in December 2009 brought several important changes in the field of EU Foreign Policy. The goal was to enhance coherence in EU external relations to strengthen the role of the EU as a global actor. The creations of the High Representative (HR) of the Union on Foreign Affairs and Security Policy and the assisting European External Action Service (EEAS) are t

Nationalekonomiska institutionen Institutionens studievägledare handhar vägledning och rådgivning angående studier i nationalekonomi, alltifrån grundkurser till kurser på avancerad nivå. Om du har problem med dina studier, har frågor om kursval eller studieupplägg, tillgodoräknande av kurser, behörigheter, examenskrav eller om du har andra relevanta frågor så är du varmt välkommen att kontakta stu

https://www.ehl.lu.se/organisation/nationalekonomiska-institutionen/studera-nationalekonomi/studievagledning - 2025-12-28

Raindance-guide: Periodiseringsnycklar i bokföringsorder Raindance-guide: Periodiseringsnycklar Innehåll Allmänt ........................................................................................................................ 1 Periodiseringsnyckel ................................................................................................... 3 Radperiodisering ........................

https://www.ekonomiwebben.lu.se/sites/ekonomiwebben.lu.se/files/2024-03/Raindance-bokforingsorder-periodiseringsnycklar.pdf - 2025-12-28

Brevmall Ansvarig för uppdatering: HR-funktionen, Kansli EHL (personal@ehl.lu.se) Kans l i EHL, HR-funkt ionen Frågor och svar om bisysslor Bisysslor ................................................................................................................ 1 Registrering av bisyssla ......................................................................................... 2 Gränser och ansvar

https://www.lusem.lu.se/internal/sites/lusem.lu.se.internal/files/2024-01/fragor-svar-bisysslor.pdf - 2025-12-28

Globalt Dynamiskt Engagemang Oceanien 2024 1GDE OCEANIEN 2024 GDE Oceanien GLOBALT DYNAMISKT ENGAGEMANG | 2024 2GDE OCEANIEN 2024 GDE Oceanien Globalt engagemang är en självklar och nödvändig del i Lunds univer- sitets arbete för att kunna fortsätta utvecklas som ett internationellt ledande universitet som värnar demokrati, mänskliga rättigheter och akademisk frihet. Globalt dynamiskt engagemang (

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2024-01/Ver%201_GDE%20Oceanien%202024.pdf - 2025-12-28