The aim of the study was to investigate the feasibility of mobilizing Philadelphia chromosome negative (Ph-) blood stem cells (BSC) with intensive chemotherapy and lenograstim (G-CSF) in patients with CML in first chronic phase (CP1). During 1994-1999 12 centers included 37 patients 556 years. All patients received 6 months' IFN, stopping at median 36 (1-290) days prior to the mobilization chemoth

Once activated, some T cells home to distinct sites in the body, such as the intestine and inflamed skin. Research in mice shows that dendritic cells in the gut produce a derivative of vitamin A, retinoic acid, that gives T cells directions.

Popular Abstract in Swedish Det finns en schablonblid av dopseden förr och nu. Lite karikerat skulle den kunna sägas se ut på följande sätt. Förr döptes alla barn. Skälen till att man döpte sina barn var djupt religiösa. Så kom baptismen och bröt barndopsseden. När baptisterna slutade döpa sina barn och sekulariseringesvågen blev allt starkare följde snart många efter. Idag döps barnen framfö alltFrom the time of the establishment of Christianity in Sweden to the middle of the Nineteenth Century all childeren were baptised. In Örebro, in central Sweden, the baptism custom was subsequently broken and weakend. Örebro is in many ways an extreme case. In 1910 only 82 percent of children were baptised. The old dodparent custom was almost extingct in 1910. The dissertation shows the course of ch

A new type of continuous, supermacroporous, monolithic, cryogel affinity adsorbent was developed, allowing specific fractionation and separation of human peripheral blood lymphocytes in a chromatographic format. The affinity adsorbent was used to design a novel cell separation strategy, which was based on the interaction of protein A from Staphylococcus aureus with cells bearing IgG antibodies on

A model based on the penetration theory has been developed to calculate the dynamic absorption rate of sulfur dioxide into a droplet of limestone slurry. The model includes both instantaneous equilibrium reactions and reactions with finite rates; limestone dissolution, sulfite oxidation, gypsum crystallization and the hydrolysis reaction of CO2. The model has been used to quantify the mass transfe

The consequences of early rheumatoid arthritis were studied in a series of patients treated at University Hospital, Lund, during the period 1985-1989. Mean disease duration at enrollment was 12 months. Most of the patients have now been followed prospectively for five years, during which time disease activity and pain have increased markedly. Ability to perform the activities of daily living (ADL)

Accurate measurements of soil water content (theta) are important in various applications in hydrology and soil science. The time domain reflectometry (TDR) technique has been widely used for theta measurements during the last two decades. The TDR utilizes the apparent dielectric constant (K-s) for estimations of theta. The K-a-theta relationship has been described using both empirical and physica

Results are presented on the photoproduction of isolated prompt photons, inclusively and associated with jets, in the gammap center of mass energy range 142 < W < 266 GeV. The cross sections are measured for the transverse momentum range of the photons 5 < E. T < 10 GeV and for associated jets with E-T(jet) > 4.5 GeV. They are measured differentially as a function of E-T(gamma), E-T(jet), the pseu

Silicon microtechnology has been used to develop a microstructure toolbox in order to enable high accuracy protein identification. During the last 2 years we developed and applied monocrystalline silicon structures and established new automated protein analysis platforms, The development of a high throughput protein platform is presented where fully automated protein identifications are performed.

Strange quarks produced in e+e--annihilation at the Z0-pole are very strongly polarized. To study to which extent this polarization is transferred to the observable hadrons would give interesting information on the hadronization mechanism. Γ-particles produced with relatively large x-values are expected to frequently contain an originally produced s-quark. We estimate that Γ-particles with x>0.3 s

A prospective bacteriologic investigation was made in 43 consecutive patients (mean age 63 years) operated on for acute cholecystitis. Gallbladder bile and wall were cultured, using four methods and with special attention to optimal anaerobic technique. Cultures were positive in 72% of the patients, yielding a wide variety of species (21 species among 48 isolates). Anaerobes constituted 23% of the

Artikel om tv-serien Band of Brothers och synen på förintelsen.