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Acute myeloid leukemia (AML) is a highly malignant disease of myeloid cell line. AML is the most frequent adult leukemia with inadequate treatment possibility. The protein phosphatases are critical regulators of cell signaling, and deregulation of protein phosphatases always contribute to cell transformation. Although many studies established a relationship between protein phosphatases and leukemi
Background: Epidemiologic studies have produced conflicting results with respect to an association of dietary fat with breast cancer. Objective: We aimed to investigate the association between fat consumption and breast cancer. Design: We prospectively investigated fat consumption in a large (n = 319 826), geographically and culturally heterogeneous cohort of European women enrolled in the Europea
The cross section for the production of W bosons with subsequent decay W -> tau nu(tau) is measured with the ATLAS detector at the LHC. The analysis is based on a data sample that was recorded in 2010 at a proton-proton center-of-mass energy of root s = 7 TeV and corresponds to an integrated luminosity of 34 pb(-1). The cross section is measured in a region of high detector acceptance and then ext
There is a wide variation in sensitivity to lead (Pb) exposure, which may be due to genetic susceptibility towards Pb. We investigated whether a polymorphism (rs1800435) in the delta-aminolevulinic acid dehydratase (ALAD) gene affected the toxicokinetics and toxicodynamics of Pb. Among 461 Chinese Pb-exposed storage battery and 175 unexposed workers, allele frequencies for the ALAD1 and ALAD2 alle
The overall aim of this thesis was to investigate utilization of medical healthcare, i.e. hospital care and outpatient care, over a period of 1 to 5 years among people aged 65 years or older. The aim was further to investigate medical healthcare utilization in relation to the predisposal factors age and sex; the enabling factors functional ability, cognitive ability, informal care, municipal long-
Ett nationellt svenskt forskningsprogram HÖGPRESTERANDE BETONG finansierat av de statliga organisationerna NUTEK och BFR och ett antal företag i byggbranschen genomfördes under åren 1991‐1997. I programmet deltog forskare från de fyra tekniska högskolorna CTH, KTH, LuTH (nuvarande LTU) och LTH. Dessutom deltog forskare från Cement och Betongforskningsinstitutet, CBI, samt forskare från olika finanA national Swedish research program HIGH PERFORMANCE CONCRETE was sponsored by the governmental organizations NUTEK and BFR and by a number of private companies within the building sector. The program was performed during the years 1991‐1997. Researchers from four Swedish technical institutes, from the Swedish Cement and Concrete Research Institute and from private companies took part in the progr
Background: Animal migration requires adaptations in morphological, physiological and behavioural traits. Several of these traits have been shown to possess a strong heritable component in birds, but little is known about their genetic architecture. Here we used 454 sequencing of brain-derived transcriptomes from two differentially migrating subspecies of the willow warbler Phylloscopus trochilus
The O, N, and C 1s core level photoemission spectra of the nucleobases cytosine and uracil have been measured in the vapor phase, and the results have been interpreted via theoretical calculations. Our calculations accurately predict the relative binding energies of the core level features observed in the experimental photoemission results and provide a full assignment. In agreement with previous
Previous research has suggested that there is a relationship between the three key components of Donabedian's conceptual model for quality assessments: structure of care, process, and outcome of care. That is, structure predicted both process and outcome of care, and better processes predict better functional outcomes and user satisfaction. The results in this study involving samples of Danish and
The evolution of electronic properties in free antimony (Sb) nanoclusters as a function of the cluster size has been studied experimentally using synchrotron radiation. Antimony 4d core-level and valence-band regions have been probed, and the 4d binding energies and valence ionization potentials of clusters of various mean sizes have been determined. The binding-energy shifts with respect to polyc
Recension av Adam Hochschild; Aldrig mera krig. Lojalitet och motstånd 1914–1918.
The sharpness and thus information content of the retinal image in the eye depends on the optical quality of the lens and its accurate positioning in the eye. Multifocal lenses create well-focused color images and are present in the eyes of all vertebrate groups studied to date (mammals, reptiles including birds, amphibians, and ray-finned fishes) and occur even in lampreys, i.e., the most basal v
Background Mixed culture enrichments have been used frequently for biohydrogen production from different feedstock. In spite of the several advantages offered by those cultures, they suffer poor H2 yield. Constructing defined co-cultures of known H2 producers may offer a better performance than mixed-population enrichments, while overcoming some of the limitations of pure cultures based on synergi
A complex of chagasin, a protein inhibitor from Trypanosoma cruzi, and papain, a classic family C1 cysteine protease, has been crystallized. Kinetic studies revealed that inactivation of papain by chagasin is very fast (k(on) = 1.5 x 10(6) m(-1).s(-1)), and results in the formation of a very tight, reversible complex (K-i = 36 pm), with similar or better rate and equilibrium constants than those f
The aim was to investigate potential risk factors and suggested injury mechanisms involved in the development of exercise-induced rib stress fractures (RSF) in elite rowers as well as investigate biomechanical and neuromuscular differences of ergometer rowing in stationary and slide-based ergometers. BMD and muscle strength was assessed as well as EMG of thoracic muscles and rowing technique duri
