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Popular Abstract in Swedish Blodet är sammansatt av många olika typer av mogna celler som är ansvariga för specialiserade roller inom blodsystemet. Röda blodceller transporterar syre till kroppens celler, vita blodceller förser oss med försvar mot mikroorganismer och blodplättar ser till att stoppa blödningar. Nybildning av blodceller behövs kontinuerligt eftersom vissa celler lever bara i några dThe blood is composed of many different cell types that through tightly regulated mechanisms are derived from hematopoietic stem cells (HSCs). In addition, HSCs are able to undergo self-renewing divisions whereby new HSCs are produced. This is an extremely important feature of HSCs in order to ensure the existence of the HSC pool that is paramount to provide life-long hematopoiesis. Aging is in ge

Recombination in the well-performing bulk heterojunction solar cell blend between the conjugated polymer TQ-1 and the substituted fullerene PCBM has been investigated with pump-probe transient absorption and charge extraction of photo-generated carriers (photo-CELIV). Both methods are shown to generate identical and overlapping data under appropriate experimental conditions. The dominant type of r

The discovery that the native PS II enzyme undergoes charge separation via an absorption extending to 730 nm has led us to re-examine the low-temperature absorption spectra of Nanba-Satoh PS II reaction centre preparations with particular focus on the long wavelength region. It is shown that these preparations do not exhibit absorption in the 700-730 nm region at 1.7 K. Absorption in the Nanba-Sat

Active surveillance of invasive group A streptococcal (GAS) infections was conducted in Denmark during 2003 and 2004 as a part of the Strep-EURO initiative. The main objective was to improve understanding of the epidemiology of invasive GAS disease in Denmark. During the 2 years, 278 cases were reported, corresponding to a mean annual incidence of 2.6 cases per 100,000 inhabitants. The vast majori

Given their wide applicability, several sparse high-resolution spectral estimation techniques and their implementation have been examined in the recent literature. In this work, we fur- ther the topic by examining a computationally efficient im- plementation of the recent SMLA algorithms in the missing data case. The work is an extension of our implementation for the uniformly sampled case, and of

Popular Abstract in Swedish Syftet med de fyra delarbeten som presenteras i denna avhandling var att studera dels utfall av fotsår samt identifiera faktorer relaterade till utfall och dels risken för att utveckla nya sår efter läkning av tidigare sår hos patienter med diabetes, fotsår och uttalad perifer kärlsjukdom. Patienter med diabetes och fotsår med ett systoliskt tåtryck <45 mmHg eller ett aThe aim of the studies presented in this thesis was to study patients with diabetes and severe peripheral arterial disease (PAD) in regard to outcomes of foot ulcers, factors related to outcomes, and occurrences of new ulcerations and amputations following healing of the initial ulcer. Patients with diabetes and a foot ulcer, consecutively presenting at a multidisciplinary foot centre, with a sys

The paper describes a novel method for calculating the residual gas fraction and the trapping efficiency in a 2 stroke engine. Assuming one dimensional compressible flow through the inlet and exhaust ports, the method estimates the instantaneous mass flowing in and out from the combustion chamber; later the residual gas fraction and trapping efficiency are estimated combining together the perfect

This paper presents a search for the t-channel exchange of an R-parity violating scalar top quark ((t) over tilde) in the e(+/-)mu(-/+) continuum using 2.1 fb(-1) of data collected by the ATLAS detector in root s = 7 TeV pp collisions at the Large Hadron Collider. Data are found to be consistent with the expectation from the Standard Model backgrounds. Limits on R-parity-violating couplings at 95

Sensory evaluation was performed to investigate how size and concentration of small rye bran particles in a continuous phase with varying viscosity influence the sensory perception of grittiness. The threshold for the sensation of grittiness of rye bran particles in a starch gel, evaluated by triangular sensory tests, was very low. The particles were discerned at a concentration of 0.1-0.3%, despi

Urothelial carcinoma shows frequent amplifications at 6p22 and 1q21-24. The main target gene at 6p22 is believed to be E2F3, frequently co-amplified with CDKAL1 and SOX4. There are however reports on 6p22 amplifications that do not include E2F3. Previous analyses have identified frequent aberrations occurring at 1q21-24. However, due to complex rearrangements it has been difficult to identify spec

Abstract COPD is a major cause of chronic morbidity and mortality throughout the world. It is a preventable and treatable disease. Smoking is the most commonly encountered risk factor for COPD and the habit now unfortunately starts at earlier ages than before. There is a strong necessity to diagnose COPD in early stages before symptoms present themselves. MRI with hyperpolarized 3He using diffusio

Background: Migration is important for the metastatic capacity and thus for the malignancy of cancer cells. There is limited knowledge on regulatory factors that promote the migration of neuroblastoma cells. This study investigates the hypothesis that protein kinase C (PKC) isoforms regulate neuroblastoma cell motility. Methods: PKC isoforms were downregulated with siRNA or modulated with activato

This paper concerns mathematical modeling and computational fluid dynamics of back-shocking during hollow fibre ultrafiltration of dextran T500. In this paper we present a mathematical model based on first Principles, i.e., solving the Navier-Stokes equation along with the continuity equation for both the solute and the solvent. We investigate the validity of the estimate On the optimal back-shock

Background: Dercum's disease is characterised by pronounced pain in the adipose tissue and a number of associated symptoms. The condition is usually accompanied by generalised weight gain. Many of the associated symptoms could also be signs of depression. Depression in Dercum's disease has been reported in case reports but has never been studied using an evidence-based methodology. The aim of this

Recent years molecular imprinting has received considerable attention as an excellent and simple approach to recognize small molecules and bioactive substances. The aim of this study is to prepare the bilirubin-imprinted supermacroporous cryogels which can be used for the adsorption of bilirubin from human plasma. N-methacryloyl(L)-tyrosinemethylester (MAT) was chosen as the preorganization monome

Planar ground float glass surfaces and the surfaces within holes are polished using fluid jet polishing (FJP) in order to improve their visual appearance or material strength. The large flexibility of FJP makes it suitable for polishing holes and other complex geometries. The influence of polishing speed, incident angle, distance, pressure, abrasive concentration, and nozzle diameter are investiga

SUMMARY Because of the strong causal relationship between persistent infections of human papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN) and cancer, HPVtesting has been proposed for improvement of cervical screening programs, including triaging and follow-up after treatment for CIN. We developed two new methods for HPV-testing with genotyping: A high-throughput HPV genotyping met

Numerous studies have been performed aimed at limiting the extent of retinal injury after ischemia, but there is still no effective pharmacological treatment available. The aim of the present study was to examine the role of tumor necrosis factor (TNF)α and its receptors (TNF-R1 and TNF-R2), especially considering the neuroretina and the retinal vasculature since the retinal blood vessels are key