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Alzheimer's disease (AD) is strongly associated with loss of synapses. The complement system has been shown to be involved in synaptic elimination. Several studies point to an association between AD and the complement system. The purpose of this study was to examine the association of cerebrospinal fluid (CSF) levels of complement components 3 and 4 (C3 and C4, respectively), and complement recept
The Middle East, home to 6.3 percent of the world’s population and containing only 1.4 percent of the world’s renewable fresh water, is experiencing an increasing water scarcity crisis.1 The UN presented an alarming report during the last World Water Forum in March 2009 painting a bleak picture of increasing demand and diminishing water supplies.2 Scientifically, the Middle East ran out of water i
The Seebeck coefficient, a key parameter describing a material's thermoelectric performance, is generally difficult to measure, and no intrinsic calibration standard exists. Quantum dots and single electron tunneling devices with sharp transmission resonances spaced by many kT have a material-independent Seebeck coefficient that depends only on the electronic charge and the average device temperat
Syftet med detta projekt är att göra uppdaterade och utvecklade livscykelanalyser för biodrivmedel som är aktuella i Sverige idag. Fokus ligger på att göra så transparenta och relevanta jämförelser som möjligt och att lyfta fram de steg i livscykeln som signifikant påverkar respektive biodrivmedels miljöprestanda. I studien görs känslighetsanalyser som visar effekterna av t ex framtida förändrade
Background: To study motor ability at seven years of age in children treated for idiopathic clubfoot and its relation to clubfoot laterality, foot status and the amount of surgery performed. Methods: Twenty children (mean age 7.5 years, SD 3.2 months) from a consecutive birth cohort from our hospital catchments area (300.000 inhabitants from southern Sweden) were assessed with the Movement Assessm
Öppna digitala Iärresurser (Open Educational Resources, OER) är undervisnings-, lärande- och forskningsmaterial som finns tillgängliga på Internet. Resurserna är öppna och fria och vanligen under creative commons licenser (cc). Beroende på licens tillåts resurserna att användas, återanvändas, spridas och även säljas öppet och fritt. Internationellt är OER-rörelsen mycket stark. I Sverige går därem
To assess how synergies between climate warming and increased concentrations of humic substances ("brownification") will affect rotifer community establishment in spring, we conducted a mesocosm experiment where we combined a 3 degrees C temperature increase with a doubling in water color, changes corresponding to modeled projections for the coming 25-75 yr. We also performed a complementary preda
BACKGROUND: Hypothermia may be accidental or therapeutic. Therapeutic hypothermia is increasingly used as treatment for various conditions, e.g., neuroprotection after cardiac arrest. Hypothermia leads to an impairment of the coagulation system, but the degree of impairment has been difficult to determine. Most studies have been performed on plasma instead of whole blood. We therefore evaluated wh
In this article, we perform a robust analysis of the determinants of U.S. swap spreads using a wide range of theoretically motivated candidate factors. We conduct an analysis by taking into consideration the interdependence between the candidate factors, as well as the time frequency under which the factors affect the spread. We find that the suggested variables can to a fair degree explain moveme
Understanding the processes generating fluctuations of natural populations lies at the very heart of academic ecology. It is also very important for applications such as fisheries management and pest control. We are interested in the effect of harvesting on population fluctuations and for that purpose we develop and analyze an age-structured model where recruitment is a stochastic process and the
This naturalistic study presents outcomes for three therapy types practiced in psychiatric public health care in Sweden. Data were collected over a 3-year period at 13 outpatient psychiatric care services participating in the online Quality Assurance of Psychotherapy in Sweden (OAPS) system. Of the 1,498 registered patients, 14% never started psychotherapy, 17% dropped out from treatment, and 36%
Popular Abstract in Swedish Alltsedan expansionen av den högre utbildningen tog fart i Sverige, i slutet av 60-talet, har universitet och högskolor arbetat för att utveckla utbildningskvaliteten. Detta har bland annat gjorts genom satsningar på policys som reglerar exempelvis arbete med kursvärderingar, mångfald, och kurs- och utbildningsplaner. Satsningar har också gjorts på pedagogisk utbildningThe focus in this thesis is to explore theoretical perspectives and strategies for academic development, particularly in a research-intensive university. The purpose is to investigate academic development that aims to support and influence individual academic teachers and groups of teachers, in the different social collegial contexts that they work in, here called microcultures. Building on litera
A measurement of the differential cross-section for the inclusive production of isolated prompt photons in pp collisions at a center-of-mass energy root s = 7 TeV is presented. The measurement covers the pseudorapidity ranges vertical bar eta vertical bar < 1.37 and 1.52
The biodegradability of dissolved organic carbon (DOC) in different fractions from the forest floor was studied. Soil leachate (SI, the soil solution in macropores which is freely drained from forest floor after rainfall), the soil matrix solution (SMS, the soil solution in meso-/micropores of the soil matrix), and soil water extracts (SWE) from two different beech forest floors were compared. Zer
Inflammation is a response to injury or pathogen invasion. A large proportion of the bodie's immune system is centred in the gastrointestinal tract (GI). Prolonged inflammatory conditions of the GI have been suggested to increase the risk for developing colon cancer. The cysteinyl leukotrienes (CysLTs), LTC4, LTD4 and LTE4 are inflammatory mediators that can bind to four known receptors, two of wh
In recent years, the 'river basin as a management unit' approach has been adopted as a solution to water management. The situation between Swaziland, Mozambique and South Africa regarding managing the water resources of the Incomati, Maputo, and Umbeluzi shared river basins is an interesting case that might need a different approach. These rivers flow downstream to the Maputo estuary where their w
