Electrochemistry of guanine and 8-oxoguanine at gold electrodes
Guanine was electrochemically oxidised at polycrystalline gold electrodes. The potential for guanine oxidation at pH 7.4 was +690 mV versus AgAgCl when extrapolated to a scan rate of 3 mV s(-1). Kinetic analysis revealed the initial irreversible 2e(-) oxidation of guanine, achieved with fast scan cyclic voltammetry. At scan rates lower than 5 V s(-1), the 2e(-) oxidation changed to the extensive 4