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A simple, efficient, and flexible procedure for the synthesis of chiral, amphiphilic, and water-soluble macrocycles is reported. Acylation of p-xylylenediamine with N-Fmoc-protected glycine, -aspartic acid, -glutamic acid, and -arginine, followed by removal of Fmoc-groups, gave amino acid:p-xylylene conjugate diamines, which were converted to ten macrocycles via stepwise urea formation using p-nit
A survey at all six medical faculties in Sweden in the spring 2004 showed that basic medical schooling (Medical School) only included an average of 59 full hours of geriatrics, with a fivefold variation between universities (19 to 106 hours). This is despite the fact that the need for geriatric skills in the health care sector is steadily increasing. A test of general knowledge in geriatrics just
This work proposes methodologies using a model-based approach to gain knowledge on and assist the development of an ion-exchange step in a protein purification process; the separation of IgG from a mixture containing IgG, insulin and transferrin. This approach is suitable for capture and intermediate steps in a process. Both methods involve four consecutive steps. Firstly, the retention of the dif
Accurate measurements of solute concentration are needed to conduct studies of solute transport process in unsaturated soil. In this paper we present a method of obtaining accurate measurements in and space using dye infiltration and image analysis. The soil color was related to the dye concentration in the soil (C-s) using 74 small calibration samples. The overall root mean square error (RMSE) 0.
Cysteine proteinases, especially cathepsin K, play an important role in osteoclastic degradation of bone matrix proteins and the process can, consequently, be significantly inhibited by cysteine proteinase inhibitors. We have recently reported that cystatin C and other cysteine proteinase inhibitors also reduce osteoclast formation. However, it is not known which cysteine proteinase(s) are involve
We compared the differences between spring and autumn in migration speed, fuelling rates and fuel loads of migrating Red Knots Calidris canutus. As a basis we used ringing data from Ottenby Bird Observatory, southeastern Sweden, collected 1948–2003, with morphometrical data from 1990–2003. Numbers ringed varied between 0 and 301 per year (average 56). Morphometrics, recoveries and recaptures of ri
Popular Abstract in Swedish Avhandlingen består av tre artiklar som med en teoretisk utgångspunkt valutamarknader och valutaprissättning. Framförallt undersöks vilken roll förväntningarna har vid prissättningen på valutor. Normalt tänker man på priset på en valuta som växelkursen, det vill säga ett pris mätt i termer av en annan valuta. Men vad är det egentligen som bestämmer den aktuella och den The thesis consists of three essays on currency markets, equilibrium and expectations. The first essay examines currency markets in the setting of a temporary equilibrium model with two currencies and two central banks, where consumers have one-point expectations. Assuming that both central banks use floating exchange rate policies it is shown that if consumers have common expectations the curren
The Swedish National Diabetes Register presents results during the period 1996-2003. Quality of care data from more than 75,000 diabetic patients (2003) treated at medical departments and primary health care centres are evaluated concerning national goals of HbA1c < 6.5% and BP < 140/85 mm Hg, the prevalence of lipid treatment, smoking etc. The national goals of HbA1c and BP were reached with incr
This paper presents a dynamic mathematical model that describes the fate and transport of two selected xenobiotic organic compounds (XOCs) in a simplified representation. of an integrated urban wastewater system. A simulation study, where the xenobiotics bisphenol A and pyrene are used as reference compounds, is carried out. Sorption and specific biological degradation processes are integrated wit
A method to determine the dynamic load between two rotating elastic helical gears is presented. The stiffness of the gear teeth is calculated using the finite element method and includes the contribution from the elliptic distributed tooth load. To make sure that the new incoming contacts which are the main excitation source are properly simulated, the necessary deformation of the gears is determi
The conductive polymer poly(2-methoxy-5-(2'-ethylhexyloxy)-1,4- phenylene vinylene) (MEH-PPV) was investigated by means of single molecule spectroscopy at 15 K. MEH-PPV single chains were deposited onto a surface from a toluene solution and covered with a polymer cap layer spin-coated from an aqueous solution for protection from air. The MEH-PPV molecules exhibited large fluorescence spectral diff
A soy protein film coating was developed and evaluated to reduce fat transfer in deep-fried foods during frying. Soy protein isolate solutions (10% SPI) with 0.05% gellan gum as plasticizer cooled after being held at 80 degrees C for 20 min provided suitable films. There was a significant fat reduction (55.12(+/-6.03)%db) between fried uncoated and coated discs of doughnut mix. The same films were
Popular Abstract in Swedish Ofärd är samhällsrisker. Riskorganisationer kan definieras som organisationer vilka genererar större samhällsrisker än traditionellt företagande. Dessa organisationer hanterar en mer omfattande kravbild än gängse företagande, en kravbild som innefattar risker för människor utanför själva verksamheten. Riskorganisationer är en del av den värdeförädling som krävs för att Risk societies are made of risk organizations. This dissertation is an ethnographic study of a risk organization, of a nuclear power plant. Risk organizations have larger demands on their organization than traditional companies have. Risk societies, to come or already present, have new political agendas. Within a risk society the major task is to reduce and distribute the negative side effects of
Popular Abstract in Swedish Syftet med avhandlingen är att undersöka bondeskapets (the peasantry)framtida existens. Analysen görs på global nivå, men framför allt på lokal nivå i samband med implikationerna av Mexikos nya jordreform från 1992. Bonden dekonstrueras i ekonomisk-och sociopolitisk aktör för att belysa hans/hennes complexitet. Försörjningsstrategier i tider då staten ersätts av markandThe thesis deals with a classical issue, that of the fate of the peasantry, in particular the process of the transformation of the peasantry. The aim is to explore whether there is a place for the smallholding peasantry in the future, or if the process of dissolution is inevitable. The discussion of this broad question is approached by first deconstructing the peasantry into economic actors and so
The role of immunoglobulin A (IgA) anti-tissue transglutaminase antibodies (IgA-tTG) as predictors of untreated celiac disease (CoD) is well documented, and the presence and levels of these antibodies are most accurately monitored with native or recombinant human antigens. However, IgA-deficient CoD patients are not identified by IgA serology, and conflicting results concerning the diagnostic vali
The anthology deals with pedagogical problems within academic teaching.
