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Capsule Regulation Shapes Klebsiella pneumoniae Pathogenesis by Balancing Adhesion, Biofilm Formation, and Intracellular Survival

Klebsiella pneumoniae is a major opportunistic pathogen, where the polysaccharide capsule is traditionally recognized as a critical virulence determinant. However, its role in surface interactions and intracellular adaptation remains incompletely understood. Here, we combined phenotypic assays with physicochemical analyses to dissect the contribution of the capsule. A wza knockout mutant display

A data-driven respiratory motion correction for pediatric DMSA renal SPECT imaging : A simulation study

Background: Technetium-99 m-dimercaptosuccinic acid (DMSA) renal cortical scintigraphy is commonly used in the evaluation of children with urinary tract infections. Pyelonephritis and post-pyelonephritic scarring manifest as renal cortical defects on DMSA renal scintigraphy, including DMSA Single Photon Emission Computed Tomography (SPECT) imaging. SPECT image quality can be degraded by blurring r

National implementation of vaginal Natural Orifice Transluminal Endoscopic Surgery for benign hysterectomies : A historical cohort study of Swedish data 2021–2023

Introduction: Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) is a technique combining vaginal entrance to the abdomen with endoscopic overview. Previous studies have shown that vNOTES decreases operating time, hospitalization, postoperative complications, and pain. We aimed to present patient demographics, costs, and surgical outcomes following the implementation of vNOTES for be

Occasio dubitandi. Expressions of Trust and Distrust Between Latin Medieval Astronomers (13th-15th c.)

This paper investigates the construction of trust in scientific inquiries and defends the importance of social epistemology in 13th century Parisian astronomy. A major issue in ancient and medieval astronomy is attributed to the difficulty of acquiring precise first-hand knowledge of astral phenomena, making collective work necessary, but raising concerns about trusting second-hand knowledge. The

Deployment Strategy for Indoor Distributed MIMO System

The physical placement of antennas is a design factor for Distributed Multiple-Input Multiple-Output (D-MIMO) systems, but finding the optimal layout is a computationally intensive, non-convex problem. Prior research often addresses this by directly optimizing the coordinates of each distributed panels using complex numerical techniques, such as convex relaxation or iterative algorithms. While via

florio HAEMO—A Digital Medical Device for Monitoring of Treatment, Symptoms and Physical Activities for People Living With Haemophilia

Introduction: Despite therapeutic achievements in haemophilia care, there is still the need to monitor and define personal treatment outcomes and document results to achieve the best possible care. Hence, a need for unbiased, timely and comprehensive real-world information exists to support informed shared decision-making regarding treatment and care. Aim: To describe a medical device for people l

Metformin and incident osteoarthritis : Causal insights from a co-twin control study

Aims: In a co-twin control design, we aimed to examine whether individuals who initiate metformin treatment have an altered risk of incident diagnosis of osteoarthritis (OA), for up to 11 years after starting the treatment, compared with their non-treated co-twin. Methods: In all twin pairs different for metformin treatment (N=1 261 pairs) and all eligible twins/singletons (N=52 341) aged 35–75 ye

När staden väntar på butiken

This study examines how the establishment of grocery retail in the urban development area of Södra Råbylund in Lund, Sweden, can be understood in terms of collaboration between municipal and private actors. The aim is to analyse how differing temporal logics, discretionary power, and governance arrangements shape the implementation of commercial services in new urban developments. The study is bas

Gränspendling och tillgänglighet från Skåne efter Öresundsbron : En rumslig analys 1997-2006

This thesis examines the development of cross-border commuting from Skåne to Denmark during the period 1997–2006, with particular attention to the role of the Öresund Bridge in facilitating increased regional integration. The study is grounded in theories of time geography, labour mobility, and center-periphery, which are used to interpret how accessibility and mobility shape participation in an i

Architecture is a luxury a broken society does not care for Seven Essays on: Current Architecture & The Human Experience

This work consists of seven essays, with each concerning a specific subject that is related to architecture. There is additional text, which pertains to this work's examination requirements for graduating the architecture-program at Lund Technical University. This work is a creative explorations through writing as a tool; through text; becoming able to formulate, conceptualize, develop and ext

Hållbara lösningar inom byggbranschen - Kommersiella byggnader

Syftet med denna uppsats är att undersöka hur vi kan bygga mer hållbara byggnader i Sverige genom att analysera materialval, byggmetoder, energieffektivitet, social hållbarhet samt ekonomiska aspekter. Målet är att identifiera konkreta åtgärder och strategier som kan bidra till ett mer hållbart samhällsbyggande. För att uppnå syftet har vi använt en kombination av kvalitativa metoder och teoretisk

Why most responder analyses are misleading

Objective: So-called responder analyses are commonly used in randomized controlled trials (RCT) for osteoarthritis and are typically based on observed change from baseline in self-reported pain. However, it is well known in the methodological literature that such responder analyses are misleading. We aimed to illustrate the size of the problem using simulation. Design: We generated individual pain

Prospective, Multicentre Feasibility Study of Remote Colon Capsule Endoscopy Using the OMOM CC100 System

Background and Aims: Colon capsule endoscopy (CCE) provides a non-invasive alternative to traditional colonoscopy. This study evaluated the feasibility, safety, diagnostic yield (DY), and patient satisfaction of the OMOM CC100 CCE system, with special focus on fully remote (n = 30) and partially remote (n = 89) administration across four centres to advance decentralised models. Methods: This prosp

Costume Dramaturgies : the dramaturgy of things in performance

With the artistic research project Costume Dramaturgies we investigate the dramaturgy that emerges when performance takes an unconventional starting point: a costume – a thing.This one year project is a continuation of the artistic research project Costume Agency (2018–2023), with a deepened focus on dramaturgy.By approaching dramaturgy as an assembly of things, we shift perspective from the human

Perspektiv på Emil Sjögren

Recension av Anders Edling och Erik Wallrup, red., Emil Sjögren – en vägvisare, 2022. Möklinta: Gidlunds förlag. 252 s. ISBN 978-91-7844-502-8.