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BackgroundAlzheimer’s disease (AD) is the most common cause of dementia and a growing healthcare challenge. Amyloid-targeting therapies (ATT) may slow progression, but implementation is limited by logistical and economic barriers. As primary care is the first contact for most patients with cognitive concerns, quantifying treatment eligibility in this setting is essential. The purpose of this study
Förberedelsebrottet infördes i svensk rätt med syfte att förhindra allvarlig brottslighet genom att kriminalisera vissa brott redan på planeringsstadiet. Förberedelsebrottet består av ett uppsåtsrekvisit, ett gärningsrekvisit och ett farerekvisit. Dessa tre delar av skuldbedömningen måste vara uppfyllda. Konkret fara måste sedermera föreligga för att straffansvar ska kunna utdömas, motsatsvis föra
Denna uppsats syftar till att undersöka hur ett vittnes anonymitet i brotts-mål kan komma att påverka rättens bedömning av vittnets trovärdighet, och om svårigheten i detta riskerar att påverka den tilltalades rättssäkerhet. Uppsatsen analyserar den nya lagen Lag (2024:11:80) om anonyma vittnen i brottsmål ur ett kritiskt perspektiv. Jag undersöker i uppsatsen huruvida faktumet att vittnet fysiskThis essay aims to examine how the anonymity of a witness in a criminal case might affect the court's assessment of the witness's credibility, and whether the difficulty in this may risk affecting the defendant's legal secu-rity. The essay analyses the new Act (2024:11:80) on anonymous witnesses in criminal cases (Lag (2024:1180) om anonyma vittnesmål) from a criti-cal perspective. In
Skiljeklausuler i anställningsförhållanden har i Sverige en lång historia. I princip kan ett avtal om skiljeförfarande träffas både som en del av ett enskilt anställningsavtal och genom kollektivavtal. Dessa klausuler kan avtalsrättsligt angripas på två tydliga sätt. För det första kan en skiljeklausul som visserligen kan anses utgöra del av avtalsförhållandet, genom exempelvis hänvisningar i anst
Det råder universell samsyn beträffande familjens egenvärde. Likaledes be-traktas barnets rätt att umgås med en förälder som det inte bor med som ett av barnrättens främsta intressen. Det är emellertid av väsentlig betydelse att ett umgänge inte kommer till stånd om det finns en risk att barnet kan komma till skada. Bedömningen är komplex och parametrarna är många, när fundamen-tala intressen stårThe right of a child to maintain a personal relation to a parent with whom the child does not live is identified as one of the primary interests of children’s rights. However, it is essential that this never happens at the expense of the child’s safety. The assessment is complex and there are many parameters to take into consideration, when two vital interests are in direct conflict. It should als
Forskningsfråga: Hur upplever enhetschefer respektive stödfunktioner i Kommunen tillit i sin organisation idag? Syfte: Syftet med studien är att öka förståelsen för hur anställda i offentlig verksamhet upplever tillit inför införandet av tillitsbaserad styrning. Vidare åsyftas att göra en jämförelse av vad tillit innebär för enhetschefer och stödfunktioner. Studiens övergripande syfte blir därResearch question: How do unit managers and support functions within the studied municipality interpret trust in their organisation today? Purpose: The purpose of this study is to increase the understanding of how employees in the public sector experience trust prior to the introduction to trust-based governance. Furthermore, it is intended to make a comparison of what trust means for unit mana
OBJECTIVE: Genome-wide association studies have begun to elucidate the genetic architecture of type 2 diabetes. We examined whether single nucleotide polymorphisms (SNPs) identified through targeted complementary approaches affect diabetes incidence in the at-risk population of the Diabetes Prevention Program (DPP) and whether they influence a response to preventive interventions. RESEARCH DESIGN
Electricity and gas prices are characterized by sharp increases or decreases in their price, followed a few days later by an equally large decreases or increases. These phenomena are called spikes or drops and are causing headaches for system developers and planners. One of the explanations for the spikes are sudden increases in demand (eg cold weather) and/or decreases in supply (eg emergency shu
Osteoporosis is a common complex disorder in postmenopausal women leading to changes in the micro-architecture of bone and increased risk of fracture. Members of the low-density lipoprotein receptor-related protein (LRP) gene family regulates the development and physiology of bone through the Wnt/β-catenin (Wnt) pathway that in turn cross-talks with the bone morphogenetic protein (BMP) pathway. In
BACKGROUND: Although the impact of pancreatic infections in acute pancreatitis has been studied extensively, there are no population-based data on extrapancreatic infections and their potential relation to organ failure. We aimed to study the occurrence of pancreatic and extrapancreatic bacterial infections in acute pancreatitis and their relation to patient outcome. PATIENTS AND METHODS: All pati
Soil contamination is a widespread problem and actions need to be taken in order toprevent damage to the groundwater and the life around the contaminated sites. InSweden more than 80.000 sites are potentially contaminated, therefore there is ademand for accurate and efficient methods for site characterization and soilremediation. In the past, the preferred methodology for soil remediation involved
Questions around school choice have attracted growing attention among educational scholars worldwide, and there is by now a burgeoning body of literature that links school choice to (i) the marketization and commercialization in education, (ii) new modes of governance in education, and (iii) individualized patterns of life-planning among families who see themselves increasingly exposed to global c
Background: Instantaneous wave-free ratio (iFR) is a coronary physiology index used to assess the severity of coronary artery stenosis to guide revascularization. iFR has previously demonstrated noninferior short-term outcome compared to fractional flow reserve (FFR), but data on longer-term outcome have been lacking. Objectives: The purpose of this study was to investigate the prespecified 5-year
The complex genetic architecture of type-2-diabetes (T2D) includes gene-by-environment (G×E) and gene-by-gene (G×G) interactions. To identify G×E and G×G, we screened markers for patterns indicative of interactions (relationship loci [rQTL] and variance heterogeneity loci [vQTL]). rQTL exist when the correlation between multiple traits varies by genotype and vQTL occur when the variance of a trait
Histology is a long standing and well-established gold standard for pathological characterizations. In recent years however, synchrotron radiation-based micro-computed tomography (SRμCT) has become a tool for extending the imaging of two-dimensional thin sections into three-dimensional imaging of tissue blocks, enabling so-called virtual histology with arbitrary clipping planes, volumetric renderi
PurposeEpithelial ovarian cancer is usually diagnosed in the advanced stages. To choose the best therapeutic approach, an accurate preoperative assessment of the tumour extent is crucial. This study aimed to determine whether the peritoneal cancer index (PCI), the amount of ascites, and the presence of cardiophrenic nodes (CPLNs) visualized by computed tomography (CT) can assess the tumour extent
