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The Relationship Between Gene Polymorphisms and Dipping Profile in Patients With Coronary Heart Disease

Background: The aim of this study is to report the relationship between certain single-nucleotide polymorphisms (SNPs) and blunted nighttime blood pressure (BP) fall in patients with coronary artery disease confirmed by coronary angiography. Methods: According to the percentage decrease in mean systolic BP (SBP) and diastolic BP (DBP) during the nighttime period, subjects were classified as dipper

Tracing Critical Realism in the Work of Åström

The aim of this chapter is to discuss the possibilities of a critical realist sociology of law set against the background of the work of Professor Karsten Åström. Thus, in the next section I give a short description of Åström’s ”sociolegal stance”, and specifically his concept of parallel norm creating processes. I then proceed, in the third section, to describe the basics of Roy Bhaskar’s critica

A PLS model for predicting rejection of trace organic compounds by nanofiltration using treated wastewater as feed

In this study a Partial Least Squares Projection of Latent Structures (PLS) model has been developed forpredicting the rejection of pharmaceutical residuals by nanofiltration (NF) using treated municipalwastewater as feed. The objective was to provide a practical tool for wastewater reuse facilities for estimatingthe rejection of emerging organic contaminants based on their physiochemical characte

Chained Approach vs Contingent Valuation for Estimating the Value of Risk Reduction

To decide how much resources to spend on reducing mortality risk, governmental agencies in several countries turn to the value of a statistical life (VSL). VSL has been shown to vary depending on the size of the risk reduction, which indicates that WTP does not increase near-proportional in relation to risk reduction as suggested by standard economic theory. Chained approach (CA) is a stated prefe

Postprandial Glucagon Reductions Correlate to Reductions in Postprandial Glucose and Glycated Hemoglobin with Lixisenatide Treatment in Type 2 Diabetes Mellitus : A Post Hoc Analysis

Introduction: The extent to which postprandial glucagon reductions contribute to lowering of postprandial glucose in patients with type 2 diabetes mellitus (T2DM) is currently unknown. The aim of this analysis was to determine whether a reduction in postprandial glucagon following treatment with the glucagon-like peptide-1 receptor agonist lixisenatide correlates with a reduction in postprandial g

Prevalence of unknown and untreated arrhythmias in an older outpatient population screened by wireless long-term recording ECG

Purpose: With longer life expectancies, the prevalence of arrhythmias is increasing; thus, there is a need for new methods to screen the older outpatient population. This population-based study describes the prevalence of arrhythmias in 200 outpatients aged ≥66 years. We also investigated the feasibility of wireless long-term recording (LTR) using the ECG-BodyKom®. Methods: Two hundred elderly per

Serotonin (5-HT) and 5-HT2A receptor agonists suppress lipolysis in primary rat adipose cells

Serotonin (5-HT) is a biogenic monoamine that functions both as a neurotransmitter and a circulating hormone. Recently, the metabolic effects of 5-HT have gained interest and peripheral 5-HT has been proposed to influence lipid metabolism in various ways. Here, we investigated the metabolic effects of 5-HT in isolated, primary rat adipose cells. Incubation with 5-HT suppressed β-adrenergically sti

Supported employment adapted for people with affective disorders : A randomized controlled trial

Background While effective vocational methods for gaining employment exist for people with schizophrenia and similar conditions, no evidence exists with regard to people with affective disorders. We aimed to study the effectiveness of a newly developed Individual Enabling and Support (IES) model adapted for the target group and compared to traditional vocational rehabilitation (TVR). Methods An as

Living with pests, pets and plants: co-habitation in contemporary gardens

The private garden can be regarded as an important part of the house-owner’s home, but it is also the home of many other living organisms. Birds and mammals, insects, worms and not least plants live their lives intermingled in the contemporary human habitations of single-house suburbs. Thus, home gardens provide plenty of material to reflect on and handle biodiversity and sustainability issues in The private garden can be regarded as an important part of the house-owner's home, but it is also the home of many other living organisms. Birds and mammals, insects, worms and not least plants live their lives intermingled in the contemporary human habitations of single-house suburbs. Thus, home gardens provide plenty of material to reflect on and handle biodiversity and sustainability issues in

MC1568 improves insulin secretion in islets from type 2 diabetes patients and rescues β-cell dysfunction caused by Hdac7 upregulation

Aims: It has in recent years been established that epigenetic changes contribute to β-cell dysfunction and type 2 diabetes (T2D). For example, we have showed that the expression of histone deacetylase 7 (HDAC7) is increased in pancreatic islets of individuals with T2D and that increased levels of Hdac7 in β-cells impairs insulin secretion. The HDAC inhibitor MC1568 rescued this secretory impairmen