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Thrombocytopenia in bacteraemia and association with bacterial species
Thrombocytopenia is common in patients with invasive bacterial infections. Bacteria can activate platelets, but it is unclear if this affects platelet count. The aim of this study was to examine whether bacteraemia with Staphylococcus aureus, which readily activate human platelets, was more likely to be complicated by thrombocytopenia than bacteraemia with Escherichia coli or Streptococcus pneumon
Immigrant Youths with Disabilities and Caregivers from the Middle-East—Challenges and Needs During Transition to Adulthood
Effects of iron on the aggregation propensity of the N-terminal fibrillogenic polypeptide of human apolipoprotein A-I
Specific mutations in APOA1 gene lead to systemic, hereditary amyloidoses. In ApoA-I related amyloidosis involving the heart, amyloid deposits are mainly constituted by the 93-residue N-terminal region of the protein, here indicated as [1-93]ApoA-I. Oxidative stress is known to be an enhancing factor for protein aggregation. In healthy conditions, humans are able to counteract the formation and th
Extended physical education in children aged 6-15 years was associated with improved academic achievement in boys
MicroRNA-dependent regulation of KLF4 by glucose in vascular smooth muscle
Diabetes is a major risk factor for cardiovascular disease and this is in part due to the effects of hyperglycemia on vascular smooth muscle cells. Small non-coding microRNAs are known to control smooth muscle phenotype and arterial contractility and are dysregulated in diabetes. The effect of microRNAs on smooth muscle differentiation is in part mediated by the transcription factor KLF4 but the r
Measuring Frailty among Older People : Further Evaluation of the Brody Frailty Index
Uptake of rheumatology biosimilars in the absence of forced switching
Moisture Buffering of Hemp-Lime with Biochar and Rape Straw-Lime as Surface Materials for a Stable Indoor Climate
An appropriate and stable indoor climate in museums is crucial to guarantee an appropriate preservation of our cultural heritage. Depending on the collection, indoor temperature and relative humidity need to be kept within a certain range. Fluctuations in temperature and relative humidity could cause damage to museum artefacts and may require higher energy needs than necessary. Biochar is a materi
Contexts of possibility in simultaneous language learning : using the L2 Motivational Self System to assess the impact of global English
Motivation in simultaneous L2 learning situations is an area of research largely overlooked and studies from contexts where people are engaged in learning more than one L2 are rare. In their large-scale Hungarian research, Dornyei, Csizer and Nemeth found that pupils' positive attitudes to one L2 could cause interferences with attitudes to others, with English being the greatest source of such int
Elite communication and affective polarization among voters
How does elite communication influence affective polarization between partisan groups? Drawing on the literature on partisan source cues, we expect that communication from in- or outgroup party representatives will increase affective polarization. We argue that polarized social identities are reinforced by partisan source cues, which bias perceptions of elite communication and result in increased
Multifractal properties of daily rainfall in two different climates
Impact analysis of energy efficiency measures in the electrolysis process in primary aluminium production
The Paris Agreement includes the goals of ‘holding the increase in the global average temperature to well below 2°C above pre-industriallevels’ and ‘making finance flows consistent with a pathway towards low greenhouse gas emissions’. Industrial energy efficiency will playan important role in meeting those goals as well as becoming a competitive advantage due to reduced costs for companies. The al
Cardiorespiratory dysautonomia in post-COVID-19 condition : Manifestations, mechanisms and management
A significant proportion of COVID-19 patients experience debilitating symptoms for months after the acute infection. According to recent estimates, approximately one out of ten COVID-19 convalescents reports persistent health issues more than three months after initial recovery. This "post-COVID-19 condition" may include a large variety of symptoms from almost all domains and organs, and for some
Glucocorticoid-mediated induction of ZBTB16 affects insulin secretion in human islets and EndoC-βH1 β-cells
Glucocorticoid use is associated with steroid-induced diabetes mellitus and impaired pancreatic β-cell insulin secretion. Here, the glucocorticoid-mediated transcriptomic changes in human pancreatic islets and the human insulin-secreting EndoC-βH1 cells were investigated to uncover genes involved in β-cell steroid stress-response processes. Bioinformatics analysis revealed glucocorticoids to exert
Exploring the potential to use in-between pixel variability for early detection of bark beetle attacked trees
The European spruce bark beetle (Ips typographus L.) is a major disturbance agent in Norway spruce (Picea abies (L.) Karst) forests in Europe and it is estimated that a changing climate will result in more severe outbreaks in the future. To reduce the risk of large outbreaks it is important to have methods that enable early detection of bark beetle attacks to help forest managers to prevent popula
Exploring the prevalence of undetected bradyarrhythmia in dementia with Lewy bodies
Local culture and change agency in old industrial places : spinning forward and digging deeper
Amylin alters human brain pericyte viability and NG2 expression
Amylin, a pancreatic β-cell-derived peptide hormone, forms inclusions in brain microvessels of patients with dementia who have been diagnosed with type 2 diabetes and Alzheimer's disease. The cellular localization of these inclusions and the consequences thereof are not yet known. Using immunohistochemical staining of hippocampus and parahippocampal cortex from patients with Alzheimer's disease an
New results for Compton scattering on deuterium : A better determination of the neutron electromagnetic polarizabilities
The electric and magnetic polarizabilities of the proton are now well known, owing to Compton scattering measurements on hydrogen targets; however, the neutron polarizabilities are still relatively uncertain, compared to the proton values. To address this problem, a multiinstitutional collaboration has conducted a program of elastic Compton scattering experiments on deuterium at the MAX IV Laborat
