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Diabetes is an increasing worldwide problem leading to major associated health issues and increased health care costs. In 2012, 9.3% of the American population was affected by diabetes, according to the American Diabetes Association, with 1.7 million of new cases since during the year (www.diabetes.org). Proteome initiatives can provide a deeper understanding of the biology of this disease and hel
PurposeThe aim of this paper is to study the rhetoric of goodwill impairment, more specifically rhetoric, as it is constructed in the form of accounts (i.e. statements that explain unanticipated or untoward behavior). The authors argue that goodwill impairment is not only a technical matter but also a rhetorical practice by means of which external scrutiny is responded to.Design/methodology/approa
For the assessment of value of new therapies in healthcare, Health Technology Assessment (HTA) agencies often review the cost per Quality-Adjusted Life-Years (QALY) gained. Some HTAs accept a higher cost per QALY gained when treatment is aimed at prolonging survival for patients with a short expected remaining lifetime, a so called End-Of-Life (EoL) premium. The objective of this study is to elici
This article aims to undertake a comprehensive cost-benefit analysis of SSAB's investment in green steel production under the HYBRIT initiative, focusing on the implications of operating within the EU Emission Trade System and an illustrative scenario employing a carbon tax. The study evaluates profitability and social benefits, utilizing time series models to forecast electricity prices in di
För närvarande står byggnadsindustrin för en betydande del av de totala utsläppen av växthusgaser i Sverige. Resurseffektiviteten är låg och de råmaterial som används i dagsläget utnyttjas inte på ett effektivt sätt. Det råder ingen tvekan om att konsumtionen av naturresurser är ett problem, något som kan förbättras genom exempelvis en ökad grad av återanvändning i materialflödet och genom att vid
The rising prevalence of type 2 diabetes among migrant populations from low- and middle-income countries (LMICs) living in high-income countries (HICs) presents a significant public health challenge. Migrants often experience lifestyle changes, socioeconomic disadvantages and barriers to accessing healthcare, which can increase their risk for type 2 diabetes. This review explores the prevention an
Gout is a chronic disease that is caused by an innate immune response to deposited monosodium urate crystals in the setting of hyperuricemia. Here, we provide insights into the molecular mechanism of the poorly understood inflammatory component of gout from a genome-wide association study (GWAS) of 2.6 million people, including 120,295 people with prevalent gout. We detected 377 loci and 410 genet
Differential heating of surface waters of lakes caused by shading from vegetation can induce convection, which could be significant for the ecosystem because the chemistry and biology can differ in the reed belt zone compared to the open lake. This process has been given little attention in the literature. In the present study surface currents just outside a reed belt as well as radiation and wate
A sizable fraction of testicular germ cell tumour (TGCT) risk is expected to be explained by heritable factors. Recent genome-wide association studies (GWAS) have successfully identified a number of common SNPs associated with TGCT. It is however, unclear how much common variation there is left to be accounted for by other, yet to be identified, common SNPs and what contribution common genetic var
Just nu befinner vi oss i en tid som har nämnts som den sjätte massutdöden. Biologisk mångfald minskar med en oroväckande hastighet och detta har stora effekter på de ekosystemtjänster som vi är beroende av och ständigt nyttjar. För att som konsument kunna bidra till att denna minskning stannar av har flertalet hållbarhetscertifieringar introducerats på marknaden, vilka har som syfte att visa vilkThe purpose of this study is to investigate how and to what extent four different sustainability certifications set standards for conserving or promoting biodiversity. This is of importance since there are a large number of certifications of different kinds on the market and as a consumer it can be difficult to navigate among these. How these certifications favor biodiversity is important to inves
