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A Capture-Recapture-based Ascertainment Probability Weighting Method for Effect Estimation with Under-ascertained Outcomes

Outcome under-ascertainment, characterized by the incomplete identification or reporting of cases, poses a substantial challenge in epidemiologic research. While capture-recapture methods can estimate unknown case numbers, their role in estimating exposure effects in observational studies is not well established. This paper presents an ascertainment probability weighting framework that integrates

The Gut Microbiota and Diabetes : Research, Translation, and Clinical Applications—2023 Diabetes, Diabetes Care, and Diabetologia Expert Forum

This article summarizes the state of the science on the role of the gut microbiota (GM) in diabetes from a recent international expert forum organized by Diabetes, Diabetes Care, and Diabetologia, which was held at the European Association for the Study of Diabetes 2023 Annual Meeting in Hamburg, Germany. Forum participants included clinicians and basic scientists who are leading investigators in

Being between life and death—experiences of COVID-19 survivors 12 to 18 months after being treated in intensive care

Purpose: This study aims to explore the experiences of care, psychosocial support, and psychosocial wellbeing among patients treated for COVID-19 in intensive care 12 to 18 months after discharge. Methods: This study used a qualitative approach with a descriptive design. Semi-structured interviews were performed with 20 adult patients treated for COVID-19 12 to 18 months after being discharged fro

The Gut Microbiota and Diabetes : Research, Translation, and Clinical Applications—2023 Diabetes, Diabetes Care, and Diabetologia Expert Forum

This article summarizes the state of the science on the role of the gut microbiota (GM) in diabetes from a recent international expert forum organized by Diabetes, Diabetes Care, and Diabetologia, which was held at the European Association for the Study of Diabetes 2023 Annual Meeting in Hamburg, Germany. Forum participants included clinicians and basic scientists who are leading investigators in

RadClim BSR – Towards a High-resolution Radar-based Precipitation Climatology for the Baltic Sea Region

Archived radar data has various applications, though it is often underutilised. Nevertheless, this information has the possibility to aid in the development of accurate and relevant climate adaptation tools, inform climate-resilient urban development strategies, and numerous other personal and societal applications. Our work in the RadClim Baltic Sea Region (BSR) project established the potential

Health Literacy among patients with end-stage kidney disease and kidney transplant recipients

Main problem: Self-management is essential for patients both before and after kidney transplantation and requires an adequate level of health literacy (HL), that is the ability to comprehend and process health information. Low HL is associated with poor clinical outcome and an increased risk of death. In Europe, HL has been scarcely studied. The aim of this study was to investigate the levels of H

Consequences on islet and incretin hormone responses to dinner by omission of lunch in healthy men

Background: Omission of breakfast results in higher glucose and lower insulin and incretin hormone levels after both lunch and dinner. Whether omission of lunch has a similar impact on the following meal is not known. Aim: This study therefore explored whether omission of lunch ingestion affects glucose, islet and incretin hormones after dinner ingestion in healthy subjects. Materials & Method

The career core of successful scientific leaders in nursing – Their motivators and strategies

Background: No studies explore the career core of successful scientific leaders in nursing, a context where role models and career support would be desirable. To achieve a successful academic career, there is a need for an in-depth understanding of how successful scientific leaders in healthcare think in order to guide junior researchers through their early careers. Aim: To explore the main concer

White Skin, Black Fuel : On the Danger of Fossil Fascism

Two trends intersect in the present: rising temperatures and the rise of the far right. What happens when they meet? In recent years, the far right has done everything in its power to accelerate the heating: an American president who believes it is a hoax has removed limits on fossil fuel production. The Brazilian president has opened the Amazon and watched it burn. In Europe, parties denying the

Implementing a feasible exercise programme in an allogeneic haematopoietic stem cell transplantation setting—impact on physical activity and fatigue

Physical exercise for patients treated with allogeneic haematopoietic stem cell transplantation (allo-HSCT) has shown positive effects on the quality of life and fatigue in experimental trials. However, there is a need for longitudinal evaluation of exercise programmes implemented in a real-world clinical setting. The aim of this prospective study was to evaluate the impact of an exercise programm

Human postprandial responses to food and potential for precision nutrition

Metabolic responses to food influence risk of cardiometabolic disease, but large-scale high-resolution studies are lacking. We recruited n = 1,002 twins and unrelated healthy adults in the United Kingdom to the PREDICT 1 study and assessed postprandial metabolic responses in a clinical setting and at home. We observed large inter-individual variability (as measured by the population coefficient of

Innovations on a shoestring: Consequences for job quality of public service innovations in health and social care

The article examines the innovation-job quality-employment nexus in social and health care in the United Kingdom and Sweden, respectively. Through seven case studies carried out with a common methodological and analytical framework in the two countries, it shows how the constraining factors of fiscal strictures derived from budgetary regimes and chronic labor shortages have two key consequences fo

The mutational constraint spectrum quantified from variation in 141,456 humans

Genetic variants that inactivate protein-coding genes are a powerful source of information about the phenotypic consequences of gene disruption: genes that are crucial for the function of an organism will be depleted of such variants in natural populations, whereas non-essential genes will tolerate their accumulation. However, predicted loss-of-function variants are enriched for annotation errors,