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Hypertension, cardiovascular risk and polymorphisms in genes controlling the cytochrome P450 pathway of arachidonic acid: A sex-specific relation?

Hypertension is a multifactorial disease in which the interplay of genetic and environmental factors that maintain blood pressure stable throughout life is altered. Cytochrome P450 (CYP)-derived metabolites of arachidonic acid such as epoxyeicosatrienoic acids (EETs) and 20-hydroxyeicosatetraenoic acid (20-HETE), active on vascular tone, endothelial function and renal sodium reapportion, have been

Power and limits of modern cancer diagnostics: cancer of unknown primary

Background: Cancer of unknown primary (CUP) is diagnosed at a metastatic stage but no diagnostic effort is spared to find the primary cancers because these will guide the treatment. Consequently, the diagnostic work-up for CUP is more comprehensive than for any other cancer, resulting in detection of second cancers unrelated to CUP. We want to use the detection rate of second cancers as a measure

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Subject-verb agreement in number (3sg - 3pl) in spoken French is a heterogeneous morpho-syntactic domain where number is expressed in some groups of verbs and in some phonological contexts only. The acquisition of this agreement is a long and gradual process (Prévost, 2009). Both children learning French as their first language (L1) and older second language (L2) learners overuse the dominant patt

Linkage study of embryopathy-Polygenic inheritance of diabetes-induced skeletal malformations in the rat

We developed an inbred rat model of diabetic embryopathy, in which the offspring displays skeletal malformations (agnathia or micrognathia) when the mother is diabetic, and no malformations when she is not diabetic. Our aim was to find genes controlling the embryonic maldevelopment in a diabetic environment. We contrasted the fetal outcome in inbred Sprague-Dawley L rats (20% skeletal malformation

Upplevelsens poetik : slöjdseminariet på Nääs 1880–1940

This dissertation examines aspects of the experience of being a student at Nääs’ sloydseminar between 1880 and 1940 and what consequences it had for the participants. The experience was more or less consciously constructed by the charismatic leader Otto Salomon and after his death in 1907 the responsability of ”composing” the experience was put on Rurik Holm, pedagogical manager between 1913 and 1

A taxonomic revision of Caloplaca herbidella and C. furfuracea

Caloplaca herbidella (Hue) H. Magn. and C. furfuracea H. Magn. are two isidiate, epiphytic species in the large genus Caloplaca. Caloplaca herbidella in a strict sense is normally grey and fertile with thick, somewhat coralloid isidia, but orange, sterile forms with thin isidia also occur. Caloplaca furfuracea is superficially similar morphologically to C. herbidella s. str. but has thinner, more

Hippocampal volume does not correlate with food-hoarding rates in the Black-capped Chickadee (Poecile atricapillus) and Willow Tit (Parus montanus)

Food-hoarding birds use memory to relocate caches, and species that store thousands of scattered food items must have an extraordinary memory capacity to be able to relocate them. Because the hippocampus is important in the functioning of spatial memory, it is logical to assume that the amount of food stored should correlate with hippocampal volume. Previously, food-hoarding capacity has been used

Effect of self-managed lifestyle treatment on glycemic control in patients with type 2 diabetes

The lack of effective, scalable solutions for lifestyle treatment is a global clinical problem, causing severe morbidity and mortality. We developed a method for lifestyle treatment that promotes self-reflection and iterative behavioral change, provided as a digital tool, and evaluated its effect in 370 patients with type 2 diabetes (ClinicalTrials.gov identifier: NCT04691973). Users of the tool h

The Stressful Memory Assessment Checklist for the Intensive Care Unit (SMAC-ICU) : Development and Testing

Stressful or traumatic memories of an intensive care stay may lead to long-term psychological morbidity. Memory assessment is therefore essential to aid in the patients’ recovery process. Acknowledging the large cohort of post ICU patients during the SARS-CoV-2 pandemic, a simple tool for the evaluation of ICU memories is needed. The aim of this study was, therefore, to develop and test the validi

Forest policy in Nordic countries : Expert opinions on future needs, uncertainties, and recommendations

There are broad calls in national and international forest policy processes for basing decision-making on the best obtainable scientific knowledge. Simultaneously, there is also a need to accommodate plural values and objectives people and society in general have associated with forests. An essential step for building an evidence base that accommodates pluralistic understandings is to capture info

What is essential? – a pilot survey on views about the requirements metamodel of reqT.org

[Context & motivation] This research preview paper presents ongoing work on the metamodel of a free software requirements modeling tool called reqT that is developed in an educational context. The work aims to make an initial validation of a survey instrument that elicits views on the metamodel of the reqT tool, which aims to engage computer science students in Requirements Engineering (RE) th