Insulin secretion from pancreatic beta-cells is controlled by complex metabolic and energetic changes provoked by exposure to metabolic fuels. Perturbations in these processes lead to impaired insulin secretion, the ultimate cause of T2D (Type 2 diabetes). To increase our understanding of stimulus secretion coupling and metabolic processes potentially involved in the pathogenesis of T2D, a compreh

Apolipoprotein A-I (apoA-I) is the main protein involved in the formation of high-density lipoprotein (HDL), it is the principal mediator of the reverse cholesterol transfer (RCT) pathway and provides cardio-protection. In addition to functional wild-type apoA-I, several variants have been shown to associate with hereditary amyloidosis. In this study we have performed biophysical and biochemical a

Abstract in UndeterminedWe analyze empirically export-price strategies across export destinations using detailed firm-product data. Most recent studies using disaggregated data to investigate why firms charge different prices for the same product on different markets focus on the cost component of prices and neglect the markup component. In this paper, we concentrate on the markup component and ex

This master's thesis reports on our investigation of how the public librarian's professional identity is formed and what it is formed of. We have considered factors such as: education, competence and daily tasks. In order to fulfil this aim we have used a literature study on concepts such as competence, education, professional identity and profession. We have also carried out an empirical

The main purpose of this Master's thesis is to investigate the new librarians' experiences and skills in the context of their present work situation and the ongoing debate about the librarian's professional identity and status. Further, the authors wanted to find out whether the new librarians' experiences and knowledge developed throughout their education correspond to the require

This thesis is the result of a case study which has its starting point in the fact that mergers and acquisitions are characterized by a high level of risk and often fail to reach stated goals such as leverage of synergy, many times due to the inability of integrating the concerned organization’s information systems. Existing problem perspectives do not include what could be a factor contributing t

Common reed is found in near-shore areas of many European lakes, where it forms dense stands. As waves are influenced by obstacles along the wave path, water and sediment motions caused by waves are affected by these stands. This study aims to evaluate the effect of common reed stands on waves, evaluate the effect of common reed stands on wave induced sediment resuspension, test a model for wave a

The purpose of this thesis is to examine how social workers perceive the concept of knowledge within social services, particularly within children and youth services. Our goal is also to study the employer's expectations and demands on graduate social workers. The main questions we address in this thesis are; What knowledge is seen as useful by employers and graduate social workers working in

The aim of this thesis is to investigate and develop a three step path for considering an optimal strategy for companies wanting to trade on the projected GHG emission market in Lithuania. An optimal strategy here is defined by two factors: financial gains by the trading company and real GHG emission reductions. The investigation included a review of the literature on the theoretical prerequisites