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The role of financial bootstrapping in handling the liability of newness in incubator businesses

Recent research in entrepreneurship has examined factors that could reduce the challenges facing new businesses (the so-called ‘liabilities of newness’). Seeking to contribute to this research, this study examines the potential role of a financial bootstrapping approach (finding ways of securing resources on favourable terms). Even though financial bootstrapping has received increased attention in

The many faces of diabetes: a disease with increasing heterogeneity

Diabetes is a much more heterogeneous disease than the present subdivision into types 1 and 2 assumes; type 1 and type 2 diabetes probably represent extremes on a range of diabetic disorders. Both type 1 and type 2 diabetes seem to result from a collision between genes and environment. Although genetic predisposition establishes susceptibility, rapid changes in the environment (ie, lifestyle facto

Pruritus in Psoriasis: A Study of Personality Traits, Depression and Anxiety.

Pruritus intensity is often not proportional to disease severity in patients with psoriasis or other pruritic dermatoses. Increasing evidence indicates that psychological factors may play an important role in the overall aetiology of pruritus. The aim of this study was to examine whether patients with psoriasis and severe pruritus differ psychologically from those with mild pruritus. In this study

Introducing an equal rights framework for older persons in residential care

This article reconceptualizes residential care for older persons by introducing a framework developed from a rights-based principle of disability policies, the normalization principle. This principle is part of the social model and states that society should make available for people who have impairments living conditions that are as close as possible to those of “others.” Using the framework on t

Null Referential Subjects in Övdalian

In this article, Övdalian null subjects are introduced and analysed. A general background to Övdalian is provided, whereupon the possible null subjects (wįð ('we') and ið ('you')) are presented. Interestingly, these null subjects do not appear in the same syntactic positions; whereas null ið seems to be unrestricted, null wįð may only appear in positions immediately preceding the finite verb. It i

Factors influencing resident's estimate of traffic-related phenomena in their street

This paper examines whether a resident's estimate of five traffic-related phenomena (accident frequency, incident frequency, difficulty of crossing the street, traffic flow, and speed level) in their neighborhood may depend on factors such as gender, age, how frequently they walk along the street or on characteristics of the street. The material consists of survey data from 919 residents living al

Mathematical modeling and statistical analysis of calcium-regulated insulin granule exocytosis in beta-cells from mice and humans.

Insulin is released from pancreatic beta-cells as a result of Ca(2+)-evoked exocytosis of dense-core granules. Secretion is biphasic, which has been suggested to correspond to the release of different granule pools. Here we review and carefully reanalyze previously published patch-clamp data on depolarization-evoked Ca(2+)-currents and corresponding capacitance measurements. Using a statistical mi

Bayesian calibration method used to elucidate carbon turnover in forest on drained organic soil

Depending on the balance between sink and source processes for C, drained organic forest soil ecosystems can be in balance or act as net sinks or sources of CO2 to the atmosphere. In order to study the effect of groundwater level and soil temperature on C-flux, the CoupModel was calibrated (climate data, groundwater levels, soil CO2 flux, net ecosystem fluxes of CO2-exchange, sensible heat flux an

Development of a disease-specific quality of life questionnaire for children & adolescents with idiopathic thrombocytopenic purpura (ITP-QoL)

Quality of life (QoL) assessment in children with coagulation disorders is a relatively unstudied area. While hemophilia-specific questionnaires (such as Haemo-QoL) are available, no instrument for children with idiopathic thrombocytopenic purpura (ITP) has been validated yet. A disease-specific questionnaire for children with ITP was therefore developed (ITP-QoL) in three phases: (a) a preparator