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Maternal diabetes during pregnancy – obstetrical considerations and long term effects

Maternal diabetes mellitus (DM) during pregnancy has detrimental health impacts on both the mother and fetus, and include increased risks of cardiac malformations, cesarean section (CS), and asphyxia. The aim of the thesis was to investigate short and long term cardiac effects after fetal exposure to DM, investigate the ability of a 5 minute Apgar score as a marker for obstetrical care, investigat

Adapt, Survive or Die - Metabolic Imbalances and the Enteric Nervous System

Abstract: In this thesis the questions “do enteric neurons adapt to survive in conditions of obesity/type 2-diabetes (T2D) related metabolic imbalances? Or do they die?” are asked. Obese and T2D patients have high rates of gastrointestinal (GI) symptoms. The GI tract comprises the body’s largest surface to the outside environment; it performs diverse and complex roles in an ever changing external

Contact Allergy to Acrylates

Acrylate contact allergy has been frequently reported since the 1970s, with hundreds of articles published in dermatology journals so far. The purpose of this thesis was to investigate the frequency of contact allergy to acrylates / methacrylates in patients with exposure to industrial, dental and nail uses of these substances. We also aimed to investigate the clinical and chemical aspects of pa

Work rehabilitation. Instrument development and women's perceptions of an intervention

The overall aim of this thesis was to contribute to the development of new instruments for use in work rehabilitation contexts and to investigate whether clients’ perceptions of their work environment changed while participating in a work rehabilitation programme, as well as how they perceived the programme. The work rehabilitation in focus was the Redesigning Daily Occupations (ReDO) programme. T

Experimental porcine models of retinal ischemia

Retinal ischaemia resulting from e.g. diabetes, vein thrombosis or arterial occlusion, is one of the major causes of visual impairment and blindness. Although new methods of treatment are being developed, there is still a need for more effective pharmacological forms of treatment. The aim of this work was to develop an appropriate animal model of retinal ischaemia in which the intracellular signal

Clinical Assessment of Axillary Lymph Nodes and Tumor Size in Breast Cancer Compared with Histopathological Examination: A Population-Based Analysis of 2,537 Women.

BACKGROUND: The clinical assessment of axillary lymph nodes status and tumor size is important for the management of patients with breast cancer. The first goal of this study was to determine the accuracy of axillary lymph node status in relation to the presence of metastases as revealed by histopathological examination. The second goal was to compare the tumor size as assessed by physical examina

Plant foods, plasma enterolactone and breast cancer - with a focus on estrogen receptor status and genetic variation

Diets high in fibre have previously been associated with decreased risk of breast cancer in the Malmö Diet and Cancer cohort. Several potent compounds may exist in high-fibre diets that might protect against breast cancer, for example lignans. Plant lignans are converted to enterolactone by the gut microflora and are similar in structure to estrogens. Enterolactone may interact with the estrogen r

Solid Oxide Fuel Cell Modeling at the Cell Scale - Focusing on Species, Heat, Charge and Momentum Transport as well as the Reaction Kinetics and Effects

Fuel cells are electrochemical devices that directly transform chemical energy into electricity. They are promising for future energy systems, since they are energy efficient, able to use renewable fuels and, when hydrogen is used as fuel, there are no direct emissions of greenhouse gases. Various improvements are made during the recent years, however the technology is still in the early phases of

Privat och offentlig regi i primärvården - En analys av produktiviteten vid privata och offentliga vårdcentraler i VG Primärvård

The question of whether private profit driven providers deliver health care with a higher productivity and efficiency in comparison to public alternatives has been a subject of debate in both political and scientific contexts The empirical research on comparisons between private and public providers has however mainly been based on experiences from U.S. hospitals. The purpose of this study is to c

Det angelägna museet : GLO - ett språk för förändring?

The point of departure for this Master’s thesis is twofold. First, the authors notice an apparent shift in focus, from collections towards the audiences, which has affected the international museum sector during the last decades. Second, they notice a change in the discourse concerning the cultural sector towards interpreting issues in economic terms. The development of the British method Generic

Short-term Abnormal Return in Hostile Takeovers

Purpose: The main purpose of this thesis is to analyse if there are any significant differences in target shareholder return between friendly and hostile takeover bids on the Scandinavian market. We also intend to investigate the differences between hostile and friendly bid characteristics, and determine to what extent these differences can be explained by; firm relatedness, method of payment, tim

How to Estimate the Economic Value of Health Care Intervention: A Methodological Study and an Illustrative Empirical Application on Diabetes

Health plays a vital role in every human’s life; and the centre for the maintaining and retaining our health lies in the health care. Thanks to innovations in health care technology and innovations of new drugs the health care is constantly improving, which contributes to improved survival probability and improved quality of life. However, this development in health care comes at a high price, sin

Buyouts - Så säkrar PE-bolaget sina intressen som majoritetsinvesterare

Riskkapitalmarknaden kan härledas så långt tillbaka som till 1940-talet då de första private equity-investeringarna genomfördes i USA, och sedan dess har branschens utsträckning ständigt förändrats i takt med det rådande ekonomiska klimatet, både hög- och lågkonjunkturer, och är idag ett starkt etablerat fenomen även i Sverige. Private equity är den investeringsform som inom samlingsbegreppet ris

Idrottande ungdomar har inte optimala kostvanor!

Idrottande ungdomar, i åldern 12-20 år, har ett specialbehov vad gäller kosten i jämförelse med andra individer. Då ungdomarna fortfarande växer och utvecklas är en sund kosthållning ytterst angeläget för upprätthållande av en normal kroppslig utveckling. Dessutom ställs i och med idrottandet högre krav på näringsintaget eftersom mer energi- och näringsämnen samt vätska förbrukas på grund av den fYoung athletes, between 12-20 years, have special dietary needs in comparison to other individuals. Since these individuals are still growing and maturing, a healthy diet is of utmost importance for the maintenance of a normal physical development. Moreover; due to physical activity the requirements of energy, nutrients and fluids are higher for young athletes. In order to achieve optimal physical