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Oxidative stress plays a role in the onset and progression of a number of diseases, such as Alzheimer’s disease, diabetes and cancer, as well as ageing. Oxidative stress is caused by an increased production of reactive oxygen species and reduced antioxidant activity, resulting in the oxidation of glutathione. The ratio of reduced to oxidised glutathione is often used as a marker of the redox state

Regional growth models leave a large share of variation unexplained. While we should continuously aim to improve these models, the unique combination of conditions and human agency in each region will also invariably lead to region-specific growth trajectories. Theoretically, we should thus expect systematic deviations from growth predictions. We propose an approach to explore these unexplained de

In the last decade, powerful communication and information technology in the form of the mobile phone has been put into the hands of more than 50% of the global population. In stark contrast, a lack of access to medical diagnostic technology with which to diagnose both communicable and non-communicable diseases will mean that many of these people will die of easily treatable conditions. Small, por

This thesis presents a three-year prospective study on metabolic characteristics of impaired glucose tolerance (IGT) and the regulation of insulin sensitivity versus islet function in relation to changes in glucose tolerance. 108 non-diabetic women aged 57-58 years were randomly selected from a population of women born in 1935 with a high prevalence of IGT. At baseline and follow-up, glucose toler

An experimental study was carried out at the Malmö School of Education in 1969 and 1970 for the purpose of studying the effects on the self-assessment of student teachers of, firstly, externally mediated self-confrontation processes (via closed-circuit television and video-recording), and secondly, dyadic confrontation processes (in the form of traditional tuto¬ring). Detailed reports on the backg

Bone morphogenic proteins, BMPs, are a group endogenous proteins that are highly conserved through evolution. The amino acid sequences of about 15 different BMPs are now known and recombinant human BMPs are commercially available. Implantation of an individual BMP protein is sufficient to induce bone formation even at a subcutaneous site. Our initial studies discovered inhibition of bone formation

Strong declines of European farmland birds in recent decades are assumed to be caused by decreased food availability resulting from agricultural intensification and concomitant loss of farmland heterogeneity. One of the species suffering particularly strong declines in NW European countries is the house sparrow. In this thesis I investigated the importance of farmland land-use on house sparrow eco