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With the triumph of the codex, medieval literature became more deeply hermeneutic in character. A vast range of texts, in various languages and genres, were not only copied with the commentaries and glosses of ancient tradition, but also underwent continuous reworking and transformation. Indeed, the very act of transcribing texts into a manuscript was often an incentive to rewrite them. This pract
Understanding the relationships between biodiversity and land-use is a key element for the development of effective conservation strategies. We studied a mid-altitude steppe-like area of Southern France, the Causse de Sauveterre, that has been grazed for many centuries. The decrease of human population during the 20th century, particularly since the end of 2nd World War, and the ongoing changes in
Popular Abstract in Swedish Populära tidskrifter och flertalet debattörer har alltsedan 80-talet hävdat att privatisering leder automatiskt till en förbättring av företagets effektivitet. På grund av dessa diskussioner har man litat mycket på marknadskrafter, då man trott att dessa krafter kan ombilda organisationer med goda effekter. Avhandlingen är en kritik mot dessa ansatser. Författaren försö
Alarm systems are used in many situations, and should be as efficient as possible. In this thesis optimal predictive alarm systems, event predictors, are presented for general linear time series models with external signals. This family of process models include e.g. AR, ARMA, ARMAX and Box-Jenkins-type models. An optimal alarm system is characterized by having the least number of false alarms, fo
Environmental protection has become high in the policy agenda of East Asian countries by the end of the last century due to both internal and external stimuli. One of the main environmental issues is the management of solid waste. The concept of circular economy which encourages reduce, reuse, and recycling, i.e. 3Rs, together with the principle of Extended Producer Responsibility (EPR) has been p
Background The pattern of cancer in long-term survivors from childhood cancer has not been investigated comprehensively. Methods We obtained a cohort of 47 697 children and adolescents aged 0-19 years with cancer as defined by the country-wide cancer registries of Denmark, Finland, Iceland, Norway, and Sweden during 1943-2005. Cohort members were followed through age 79 years for subsequent primar
Since Abney (1987), generative syntax has invested much interest in the structure of the Noun Phrase, producing numerous theoretical as well as descriptive studies. Within the field of Scandinavian Noun Phrase studies, Delsing (1993) was a groundbreaking work that has since been followed up by several important studies, including Vangsnes et al. (2003) and Julien (2005). This field of inquiry is e
BACKGROUND:: Exposure to second-hand smoke has been shown to be associated with increased cardiovascular mortality in several, but not all, epidemiologic studies. Our aim was to investigate the risk of circulatory death associated with exposure to second-hand smoke in never-smokers in a very large prospective study, the European Prospective Investigation into Cancer and Nutrition. A secondary aim
In NW Patagonia, Argentina, poor regeneration after fires of Nothofagus pumilio (Poepp. and Endl.) Krasser forests located in drier environments has been attributed to probable edaphic changes. We studied the long-term effects of wildfire on the mineralogical, physical, chemical and biological properties of a soil developed from volcanic-ashes under N. pumilio forests. Soils from six small patches
On the basis of cross-sectional studies in elite athletes and longitudinal studies, physical activity in growing children has been suggested to enhance bone mineral acquisition and prevent osteoporosis later in life. The level of exercise in most of these studies is not applicable in a population on a day-to-day basis. The aim of this study was to determine whether moderate increased exercise with
A cloud system resolving model including photo-chemistry (CSRMC) has been developed based on a prototype version of the Weather Research and Forecasting (WRF) model and is used to study influences of deep convection on chemistry in the TOGA COARE/CEPEX region. Lateral boundary conditions for trace gases are prescribed from global chemistry-transport simulations, and the vertical advection of trace
We search for signatures of past accretion events in the Milky Way in the recently published catalogue by Nordstrom et al., containing accurate spatial and kinematic information as well as metallicities for 13 240 nearby stars. To optimize our strategy, we use numerical simulations and characterize the properties of the debris from disrupted satellites. We find that stars with a common progenitor
Oral contraceptive (OC) use in young women has been associated with an increased risk of breast cancer. This matched case-control study aims to elucidate the combined effects of OC use and genetic factors in a population-based series of BRCA1/2 mutation-tested early-onset breast cancers. A first invasive breast cancer was diagnosed in 259 women aged <= 40 years between 1990 and 1995 in the South S
We have investigated the inhibition of the recently identified family C13 cysteine peptidase, pig legumain, by human cystatin C. The cystatin was seen to inhibit enzyme activity by stoichiometric 1:1 binding in competition with substrate. The Ki value for the interaction was 0.20 nM, i.e. cystatin C had an affinity for legumain similar to that for the papain-like family C1 cysteine peptidase, cath
The genetic polymorphism of Borrelia burgdorferi and Borrelia afzelii, two species that cause Lyme borreliosis, was estimated by sequence typing of four loci: the rrs-rrlA intergenic spacer (IGS) and the outer-membrane-protein gene p66 on the chromosome, and the outer-membrane-protein genes ospA and ospC on plasmids. The major sources of DNA for PCR amplification and sequencing were samples of the
Basal cell carcinoma cells show low proliferation rates at the invasive front and a concordant upregulation of the cdk-inhibitor p16, limiting proliferative capacity. Little is known about the mechanisms of p16 regulation in normal and malignant cells apart from that many transcription factors such as Ets1, Ets2, SP1, SP3, JunB and the polycomb protein Bmi1 have the potential to induce or repress
Crucian carp from populations that lack piscivores are extremely vulnerable to predation. However, in the presence of piscivores these fish develop an inducible morphological defence, a deep body. This switch from a vulnerable, shallow-bodied morph to a morphologically defended morph makes this species very suitable for investigations of anti-predator strategies, and trade-offs between morphologic
In recent years evidence has emerged that the amount of isoprene emitted from a leaf is affected by the CO2 growth environment. Many - though not all - laboratory experiments indicate that emissions increase significantly at below-ambient CO2 concentrations and decrease when concentrations are raised to above-ambient. A small number of process-based leaf isoprene emission models can reproduce this
