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Kompetent aktör eller psykiskt skör? : Barn- och flickdiskurser i konstruktionen om ungas psykiska ohälsa

Mental health problems among children and youth is positioned as one of the most urgent public health issues in Sweden today. Both research and official reports assert that mental health issues have increased among adolescents, especially girls, during the last decades. The aim of this study is to investigate how changes in childhood and gender discourses has implicated the construction of young p

Aberrant receptor tyrosine kinase signaling in lipofibromatosis : a clinicopathological and molecular genetic study of 20 cases

Lipofibromatosis is a rare pediatric soft tissue tumor with predilection for the hands and feet. Previously considered to represent “infantile fibromatosis”, lipofibromatosis has distinctive morphological features, with mature adipose tissue, short fascicles of bland fibroblastic cells, and lipoblast-like cells. Very little is known about the genetic underpinnings of lipofibromatosis. Prompted by

Detecting TP53 mutations in diagnostic and archival liquid-based Pap samples from ovarian cancer patients using an ultra-sensitive ddPCR method

High-grade serous ovarian cancer (HGSOC) is the most common subtype of epithelial ovarian cancer and early detection is challenging. TP53 mutations are a hallmark of HGSOC and detection of these mutations in liquid-based Pap samples could provide a method for early diagnosis. Here we evaluate the use of IBSAFE, an ultra-sensitive droplet digital PCR (ddPCR) method, for detecting TP53 mutations in

Revolving permanent magnet causes rotating particle motion that makes new detection schemes possible in magnetomotive ultrasound

Magnetomotive ultrasound, MMUS, can reveal the presence of a magnetic contrast agent by applying an external magnetic field. If the interaction between the agent and the field is strong enough, a movement that can be detected by ultrasound is induced in the surrounding tissue, thereby inferring the contrast agent distribution. Electromagnets have been used to generate the necessary magnetic field,

Health Literacy Among Swedish Lung Transplant Recipients 1 to 5 Years After Transplantation

INTRODUCTION:: Understanding medical information and self-management ability is vital for good quality of life among transplant recipients. However, health literacy (HL) has never been investigated among lung transplant recipients. OBJECTIVE:: This study investigated HL among Swedish lung transplant recipients 1 to 5 years after lung transplantation in relation to recovery, fatigue, adherence, cog

The Galah Survey : Classification and Diagnostics with t-SNE Reduction of Spectral Information

Galah is an ongoing high-resolution spectroscopic survey with the goal of disentangling the formation history of the Milky Way using the fossil remnants of disrupted star formation sites that are now dispersed around the Galaxy. It is targeting a randomly selected magnitude-limited (V ≤ 14) sample of stars, with the goal of observing one million objects. To date, 300,000 spectra have been obtained

Under-five mortality and maternal HIV status in Tanzania: analysis of trends between 2003 and 2012 using AIDS Indicator Survey data

BackgroundMortality among children under five remains a significant health challenge across sub-Saharan Africa. HIV/AIDS is one of the leading contributors to the relatively slow decline in under-five mortality in this region. In Tanzania, HIV prevalence among under-five children is high and 90% of all infections are due to mother-to-child transmission.ObjectivesThe study aimed to examine the asso

'I would never have done it if it hadn't been digital' : a qualitative study on patients' experiences of a digital management programme for hip and knee osteoarthritis in Sweden

OBJECTIVES: To investigate the experiences of a digital management programme for hip and knee osteoarthritis (OA), including education and exercises as well as an option to chat with an assigned physical therapist for feedback, questions and support.SETTING: This study was conducted at a regional hospital in the southern part of Sweden.METHODS: Nineteen patients (10 women), median age of 66 (q1-q3

Societal cost of oropharyngeal cancer by human papillomavirus status, cancer stage, and subsite

Background The incidence of oropharyngeal cancer (OPC) is increasing, particularly human papillomavirus (HPV)-associated OPC. The aim of this study was to specify the total societal cost of OPC by HPV status, cancer stage, and subsite using a bottom-up cost-of-illness approach. Methods We analyzed 121 consecutive patients with OPC from the Southern Health Care Region of Sweden. We estimated the di

Being political in the media : Political identities in journalistic and Twitter discourse

This thesis is about the role of media discourse in shaping the political identities of those who want to be heard in public. The ways in which people are able to speak, know, and feel in political situations have important implications for how we conceive of the possibilities to be engaged in contemporary democracy. This thesis offer four empirical studies of how political identities are construc

Engineering the extracellular matrix to model diseases and orchestrate regeneration

The extracellular matrix is not only a scaffold to which cells attach, but it is also a matrix that communicates cell signals. Because of the interplay between cells and the extracellular matrix, changes in the extracellular matrix can steer cell fate. This opens up the opportunity to design and engineer the extracellular matrix to communicate changes to the cells. Thus, this thesis has focused on

TESS and CHEOPS discover two warm sub-Neptunes transiting the bright K-dwarf HD 15906

We report the discovery of two warm sub-Neptunes transiting the bright (G = 9.5 mag) K-dwarf HD 15906 (TOI 461, TIC 4646810). This star was observed by the Transiting Exoplanet Survey Satellite (TESS) in sectors 4 and 31, revealing two small transiting planets. The inner planet, HD 15906 b, was detected with an unambiguous period but the outer planet, HD 15906 c, showed only two transits separated

The Association Between HIV Diagnosis Disclosure and Adherence to Anti-retroviral Therapy among Adolescents Living with HIV in Sub-Saharan Africa: A Systematic Review and Meta-Analysis

IntroductionNine in ten of the world’s 1.74 million adolescents living with human immunodeficiency virus (ALHIV) live in Sub-Saharan Africa. Suboptimal adherence to antiretroviral therapy (ART) and poor viral suppression are important problems among adolescents. To guide intervention efforts in this regard, this review presented pooled estimates on the prevalence of adherence and how it is affecte

The Secrets of Plastic Language Revealed : Multimodality, Polysemiosis, and Iconicity

The notion of “plastic language” (or, as we will say in the following, the plastic layer) of the picture goes back to French structuralism, where it was supposed, just like “iconic language”, to be fundamentally based on arbitrary conventions. Nobody nowadays takes seriously the idea of depiction being purely conventional, but we will argue that the same counterclaim should be made with regard to

Influence of hydrothermal alteration on the elastic behaviour and failure of heat-treated andesite from Guadeloupe

Studies on the mechanical behaviour of rocks, including volcanic rocks, usually seek for unaltered and simple material: rocks without macroscopic defects. However, volcanic rocks are often naturally altered due to the circulation of hydrothermal fluids. This alteration may influence mechanical and physical properties. Here, we study the effect of hydrothermal alteration on the elasticity and failu

Late Adverse Effects after Treatment for Childhood Acute Leukemia

The aim of this review is to raise awareness and knowledge among healthcare professionals and policymakers about late adverse effects in survivors of childhood leukemia. With contemporary treatment, over 90% of children with acute lymphoblastic leukemia (ALL) and over 60% with acute myeloid leukemia (AML) are cured. Large cohort studies demonstrate that 20% of ALL and most AML survivors have at le

Tourist information behaviour on site: smartphones and planned serendipity

Smartphones have become one of the main tools for travel information search, especially on site, during the trip. The use of mobile technologies and ubiquitous internet connectivity do not only allow tourists to access information anywhere, at any time, but have deep impacts on tourists’ behaviours and on their whole tourist experience.The study suggests an interpretation of tourists’ information

Interactive Interventions can Improve Hand Hygiene and Aseptic Techniques During Perioperative Care – Experience From the “Safe Hands” Project

Purpose: This paper evaluates a theory-driven, interactive hand hygiene (HH) intervention, the Safe Hands project, based on theories of organizational learning and culture including leadership support, dialogue and co-creation. Design: This prospective quasi-experimental study used unobtrusive overt observations to evaluate adherence to HH recommendations after implementing an infection-prevention

Population Exposure to Organic Contaminants and Human Biomonitoring

We are surrounded by various chemicals, both naturally occurring and synthetically produced. Some, but not all, chemicals can be hazardous for human health following exposure, especially for vulnerable population groups including children, adolescents, and pregnant women. The increased use and production of chemicals have contributed positively to society in numerous ways, while also resulting in

Probing Majorana modes via local spin dynamics

We investigate Majorana modes in a quantum spin chain with bond-dependent exchange interactions by studying its dynamics. Specifically, we consider two-time correlations for the anisotropic Kitaev-Heisenberg (KH) Hamiltonian close to the so-called Kitaev critical point. Here the model coincides with a phase boundary of two uncoupled instances of Kitaev's model for p-wave superconductors, together