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A series of azaflavone derivatives and analogues were prepared and evaluated for their affinity to the benzodiazepine binding site of the GABA(A) receptor, and compared to their flavone counterparts. Three of the compounds, the azaflavones 9 and 12 as well as the new flavone 13, were also assayed on GABA(A) receptor subtypes (alpha(1)beta(3)gamma(2s), alpha(2)beta(3)gamma(2s), alpha(4)beta(3)gamma

Popular Abstract in Swedish Syfte Syftet med denna avhandling var att undersöka om barn födda i Sverige till invandrare (icke-Svenskar) hade en ökad risk för typ 1 diabetes (T1D) och om immunogenetiska markörer för T1D (HLA och icke-HLA genetiska faktorer samt ö-cellsantikroppar) skiljde sig från svenska T1D barn (Svenskar). Målsättningen var också att analysera ärftliga förutsättningar (T1D och TThis thesis examined whether the offspring of immigrants (non-Swedes) to Sweden are at increased risk of Type 1 Diabetes (T1D) when they are born or live in Sweden. It also evaluated if their T1D and T2D-related genes differed from Swedish patients and whether this genetic heritage determined the types and existence of islet autoantibodies at time of diagnosis and affected the classification of di

The Sustainable Development Goals (SDGs) require nations to ensure adequate water supply for all. For Kazakhstan, this means that rural areas will need much stronger attention as they have been rather neglected in efforts to comply with the Millennium Development Goals (MDGs). This study aims to establish a baseline data concerning the current situation in villages that will need interventions acc

År 1960 upptäcktes Cesium-137-aktivitet från atmosfäriska kärnvapenprovvid mätningar på lågaktivitets laboratoriet iLund. Denna händelse initierade mätningar av den svenska samiska befolkningen och iprodukter från ren som betar i de svenska fjällen. En semi-bärbarhelkropps detektor konstruerades med en detektionsgräns för 137Cs som var tillräckligt bra för att mäta människor med högakroppskoncentrIn 1960 Caesium-137 activity from atmospheric nuclear weapons test was dis-covered in measurements at the whole body gamma-ray counting laboratory inLund. This event initiated measurements of the Swedish Sami population, and inproducts from reindeer that bite lichens in the Swedish mountains. A semi-portable whole-body counter designed with a detection limit for 137 Cs at high radiation background

Background: Overweight and obesity were recently associated with a poor prognosis in patients with autosomal dominant polycystic kidney disease (ADPKD). Whether the metabolic consequences of obesity as defined by the metabolic syndrome (MS) are also linked with disease progression remains untested. Methods: Eligible ADPKD patients with different stages of CKD (n = 105) and 105 non-diabetic control

Many studies have demonstrated the existence of simple, unidimensional socioeconomic gradients in body mass index (BMI). However, in the present paper we move beyond such traditional analyses by simultaneously considering multiple demographic and socioeconomic dimensions. Using the Spanish National Health Survey 2011–2012, we apply intersectionality theory and multilevel analysis of individual het

Abstract: In the cerebral cortices of rats, during insulininduced hypoglycemia, changes in the concentrations of labile phosphate compounds [ATP, ADP, AMP, and phosphocreatine (PCr)] and glycolytic metabolites (lactate, pyruvate, and glucose) as well as phospholipids and free fatty acids (FFAs) were studied in relation to extracellular potassium and calcium activities. Changes in extracellular cal

BACKGROUND: Human papillomavirus types 16 (HPV-16) and 18 (HPV-18) cause approximately 70% of cervical cancers worldwide. A phase 3 trial was conducted to evaluate a quadrivalent vaccine against HPV types 6, 11, 16, and 18 (HPV-6/11/16/18) for the prevention of high-grade cervical lesions associated with HPV-16 and HPV-18. METHODS: In this randomized, double-blind trial, we assigned 12,167 women b

Forskningsingenjör Kontaktinformation E-post: tobias [dot] biermann [at] cec [dot] lu [dot] seOrganisation Miljö- och geovetenskapliga institutionen (MGeo) Hämtställe: 16 WebbplatsTobias Biermanns profil i Lunds universitets forskningsportalAndra roller Forskningsingenjör ICOS Sweden Forskningsingenjör Institutionen för naturgeografi och ekosystemvetenskap Medlem i Strategiskt forskningsområde BEC

https://www.cec.lu.se/sv/tobias-biermann - 2025-12-21

https://www.intramed.lu.se/en/anette-welin - 2025-12-21

https://www.intramed.lu.se/en/anna-e-larsson - 2025-12-21

https://www.medicine.lu.se/frida-reisdal - 2025-12-21

Visiting research fellow Contact details Email: sebastian [dot] barrientos_baeza [at] med [dot] lu [dot] seOrganisation Molecular Tumor Pathology Visiting address: Medicon Village, Building 404 A3, Sheelevägen 2, Lund Room number: MV 404A3 Service point: 90 WebpageSebastián Barrientos Baezas profile in Lund University research portalOther affiliations Affiliated researcher Integrative Neurophysiol

https://www.ai.lu.se/sebastian-barrientos-baeza - 2025-12-21

The purpose of this study was to investigate whether police officers who have been exposed to threats and violence in their profession have a higher degree of Posttraumatic Growth, PTG. PTG was measured in relation to threats and violence on the following parameters; psychological management, reactions which included current feelings of threat/anxiety and psychological influence. The respondents i

Globalization is an increasingly pervasive factor in the economy, and due to the increasingly international market and competition, it is becoming progressively difficult for firms in traditional, mature industries in high-wage countries to remain competitive. This thesis highlights the case of the Småland-Blekinge region that is performing paradoxically well, largely due to a manufacturing indust

When performing a QRA you have to consider a number of accident scenarios. How many scenarios you choose often determines the time and resources needed to perform the QRA. The report investigates the possibility that a QRA can be performed using only a few representative scenarios. Further it presents a discussion on how these scenarios should be constructed.

This thesis examines the blog ‘Alla Dessa Dagar’ by the Swedish Minister of Foreign Affairs Carl Bildt; one of the pioneer politicians using social media to broadcast political messages. Based on role theory and theories covering social media, with capacities of democratization and blurring between public and private, the focus of the study is twofold. To begin with the study aims to identify how

With climate change gathering pace and increasingly foreboding predictions of the effects it will bring, the question of how to achieve a fast-paced transition towards a sustainable society is gaining increased awareness and importance. One debate centers on agency, and whether primarily public authorities can govern such a transition successfully. Theory on transitions suggests that they are ofte

Den här studiens primära syfte är att jämföra och utvärdera två medborgardialogs metoder. De två metoderna är samrådsmöten och Public participatiory GIS (PPGIS). Samrådsmöten är en etablerad metod inom medborgardialog för samhällsplanering i Sverige. Uppsatser syftar till att pröva hypotesen om PPGIS är en effektivare metods för medborgardialog. Uppsatsen utvärderade först de två metoderna med hThe primary purpose of this study is to compare and evaluate two public participation methods. The two methods are public meetings and Public participatory GIS (PPGIS). Public meetings are an established public participation method for urban planning in Sweden. The thesis aims to test the hypothesis if PPGIS is more effective as a public participation method. The thesis first evaluated the two me

"Here, there is only love" - A qualitative interview study about the players experience of the football team Gatans Lag The aim of this study was to describe and analyse how the players on the Swedish football team Gatans Lag experience how the organisation contributes to their life situation. The study was based on eight semistructured interviews with players from the team. During the