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Sensemaking in the Digital Workplace, A Case Study of Organizational Identity Construction via ISM at Tencent

Internal social media (ISM) platforms have transformed internal communication by enabling dialogue, participation, and shared meaning-making across organizational hierarchies and locations. While previous research has highlighted ISM’s role in knowledge sharing and employee engagement, less attention has been paid to its function in shaping organizational identity from a managerial perspective. Th

Systemic Risk and Default Contagion in Financial Networks: Identifying Systemically Important Banks

This thesis uses real data from the Bank of International Settlements to create financial networks for the interbank market using five different methods for network reconstruction. The goal is to analyze how defaults propagate to assess the importance of banks and to examine how the network’s structure affects the system’s vulnerability. By applying network theory, communicability theory, and the

Ficolin-1 is present in a highly mobilizable subset of human neutrophil granules and associates with the cell surface after stimulation with fMLP

Ficolins are soluble molecules that bind carbohydrate present on the surface of microorganisms and function as recognition molecules in the lectin complement pathway. Three ficolins have been identified in humans: ficolin-1, ficolin-2, and ficolin-3. Ficolin-1 is synthesized in monocytes and type II alveolar epithelial cells. Ficolin-1 has been shown to be present in secretory granules of human ne

Boosting customers’ impulsive buying tendency in live-streaming commerce: The role of customer engagement and deal proneness

With the ever-growing popularity of live-streaming commerce, it is crucial for marketers to understand how live-streaming contributes to sales. While prior studies mainly focused on customer motivations for using live-streaming commerce, few studies, to date, elucidate consumers' decision-making process in this context. Addressing this gap, we adopt the Elaboration Likelihood Model (ELM) of persua

Politics of middlemen and political society

Some of the most pressing debates in development studies have concerned the relative merits of states and markets, or the means by which markets might be regulated by a range of public institutions from the local to the global scale. These debates have taken shape, most famously, in the contrasting cases of sub-Saharan Africa and East Asia, and they have an obvious and continuing relevance in coun

Multiplex genome editing eliminates lactate production without impacting growth rate in mammalian cells

The Warburg effect, which describes the fermentation of glucose to lactate even in the presence of oxygen, is ubiquitous in proliferative mammalian cells, including cancer cells, but poses challenges for biopharmaceutical production as lactate accumulation inhibits cell growth and protein production. Previous efforts to eliminate lactate production in cells for bioprocessing have failed as lactate

Wind turbines and seismic hazard : A state-of-the-art review

Wind energy is a rapidly growing field of renewable energy, and as such, intensive scientific and societal interest has been already attracted. Research on wind turbine structures has been mostly focused on the structural analysis, design and/or assessment of wind turbines mainly against normal (environmental) exposures while, so far, only marginal attention has been spent on considering extreme n

Quinoline-triazole half-sandwich iridium(iii) complexes : Synthesis, antiplasmodial activity and preliminary transfer hydrogenation studies

Iridium(iii) half-sandwich complexes containing 7-chloroquinoline-1,2,3-triazole hybrid ligands were synthesised and their inhibitory activities evaluated against the Plasmodium falciparum malaria parasite. Supporting computational analysis revealed that metal coordination to the quinoline nitrogen occurs first, forming a kinetic product that, upon heating over time, forms a more stable cyclometal

Molecular evolution of coxsackievirus A24v in Cuba over 23-years, 1986–2009

Coxsackievirus A24 variant (CVA24v) is a major causative agent of acute hemorrhagic conjunctivitis outbreaks worldwide, yet the evolutionary and transmission dynamics of the virus remain unclear. To address this, we analyzed and compared the 3C and partial VP1 gene regions of CVA24v isolates obtained from five outbreaks in Cuba between 1986 and 2009 and strains isolated worldwide. Here we show tha

Using semantic role labeling to predict answer types

Most question answering systems feature a step to predict an expected answer type given a question. Li and Roth \cite{li2002learning} proposed an oft-cited taxonomy to the categorize the answer types as well as an annotated data set. While offering a framework compatible with supervised learning, this method builds on a fixed and rigid model that has to be updated when the question-answering domai

Identification of bacterial and fungal components in tobacco and tobacco smoke.

ABSTRACT: The microbiological composition of tobacco products was studied using culture and chemical analysis (of tobacco leaves) or chemical analysis only (tobacco and tobacco smoke). The chemical analyses utilized gas chromatography-tandem mass spectrometry for determining 3-hydroxy fatty acids, muramic acid, and ergosterol as markers of respectively lipopolysaccharide (LPS), peptidoglycan, and

Volcanic influence on centennial to millennial Holocene Greenland temperature change

Solar variability has been hypothesized to be a major driver of North Atlantic millennial-scale climate variations through the Holocene along with orbitally induced insolation change. However, another important climate driver, volcanic forcing has generally been underestimated prior to the past 2,500 years partly owing to the lack of proper proxy temperature records. Here, we reconstruct seasonall

Regulation of tissue factor-induced signaling by endogenous and recombinant tissue factor pathway inhibitor 1

Tissue factor (TF) triggers upstream coagulation signaling via the activation of protease-activated receptors (PARs) of relevance for inflammation and angiogenesis. TF pathway inhibitor 1 (TFPI-1) is the physiologic inhibitor of TF-initiated coagulation, but its role in regulating TF signaling is poorly understood. Here, we demonstrate that endogenous, endothelial cell-expressed TFPI-1 controls TF