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Closed-Loop Switched Capacitor Cuk Converter Topology for Voltage Regulation and PFC Applications

Converters of AC-DC nature are pivotal to supplying power in electronics, charging equipment, and renewable energy integration. A closed-loop Cuk converter with switched capacitor network and PID controller was proposed in this paper to mitigate the limitations of open circuit Cuk converter topology to ensure improved power factor from input along with low distortion in output, making it ideal for

Aedas R&D : global practices of computational design

This paper gives an overview of the approach of working methods at the Aedas R&D Computational Design and Research [CDR] Group. It first contextualizes research in architectural practice and tries to propose an explanation for the difficulties in implementing it; then explains the evolution of the groups' computing approach from bespoke to heuristic sets of lightweight applications. It conclud

Characterization and Toxic Potency of Airborne Particles Formed upon Waste from Electrical and Electronic Equipment Waste Recycling : A Case Study

Manual dismantling, shredding, and mechanical grinding of waste from electrical and electronic equipment (WEEE) at recycling facilities inevitably lead to the accidental formation and release of both coarse and fine particle aerosols, primarily into the ambient air. Since diffuse emissions to air of such WEEE particles are not regulated, their dispersion from the recycling plants into the adjacent

On Textile Reuse : Recycling and Resource Management in the Long Eighteenth Century

Reuse and recycling were important, but often forgotten, parts of managing the preindustrial fashionable wardrobe. Through researching diaries and extant garments from Swedish collections, the sources reveal everyday textile practices of costly textiles, mending, turning, altering, using old fabric or garments for new, change of parts or color, and reuse of textile material for new fabrics. The so

ALBA : Adaptive Language-Based Assessments for Mental Health

Mental health issues differ widely among individuals, with varied signs and symptoms. Recently, language-based assessments have shown promise in capturing this diversity, but they require a substantial sample of words per person for accuracy. This work introduces the task of Adaptive Language-Based Assessment (ALBA), which involves adaptively ordering questions while also scoring an individual’s l

Evidence and evidence gaps in assessments and interventions in areas related to social work research and practice : an overview of four evidence maps

This overview of four evidence maps is based on systematic reviews of assessment and interventions in social work practice. The aim was to investigate the evidence and evidence gaps within four important areas for social work research and practice. Descriptive data on search strategies and domains were collected from four evidence maps, on Social Assistance, Substance Dependence, Care for older ad

DNA movement in sub-20 nm nanoslits

The movement of XbaI digested O-DNA in 20 nanometer and O-DNA in 12 nanometer high slits was investigated. We found that DNA moved intermittently and following preferential pathways, indicating an important influence of surface roughness. From these intermittent movements two different mobilities were calculated, the total averaged mobilities and averaged mobilities between the intermittent sticki

Transcriptomic profiling of T-cell populations in non-muscle invasive and muscle invasive bladder cancer.

Background: Bladder cancer is categorized as non-muscle invasive (NMIBC) or muscle invasive (MIBC). NIMBC makes up around 70% of the cases and although it is less aggressive, the recurrence rate is 50-70%, thus requiring extensive monitoring. Additionally, there is a risk of progression into MIBC with a 5-year survival of only 50% even when treated with radical cystectomy. Immune checkpoint inhibi

Physiological and behavioral responses in human fear of bears and wolves.

Research on human emotions towards large carnivores is often based on self-reported emotions. This study aimed to investigate physiological and behavioral responses to feared animals among people who say that they are fearful or not fearful of brown bear and wolf. Participants were recruited to be bear fearful only (n=8), fearful of both bear and wolves (n=15), or fearful of neither carnivore (n=1

Hazard Analysis of Collision Avoidance System using STPA

As our society becomes more and more dependent on IT systems, failures of these systems can harm more and more people and organizations both public and private. Diligently performing risk and hazard analysis helps to minimize the societal harms of IT system failures. In this paper we present experiences gained by applying the System Theoretic Process Analysis (STPA) method for hazard analysis on a

Quantifying the Impact of Different Parameters on Optimal Operation of Multi-Microgrid Systems

The multi-objective optimal power management of multi-microgrid systems is solved in this paper. Minimizing the total cost and emission of the system are considered as the objective functions. The multi-objective particle swarm optimization algorithm is applied on a multi-microgrid system that consists of four microgrids each includes diesel generators, wind turbines, photovoltaic units, battery,

Allergic inflammation in lungs and nasal epithelium of rat model is regulated by tissue-specific miRNA expression

Introduction: Atopic asthma and allergic rhinitis are common chronic inflammatory diseases affecting lower airways and nasal mucosa, respectively. Several reports demonstrated frequent co-occurrence of these two diseases, however, the exact molecular mechanism has not been described. The present study aimed to investigate if small non-coding RNA might be responsible for the co-occurrence of asthma

Airspace Dimension Assessment with Nanoparticles (AiDA) in Comparison to Established Pulmonary Function Tests

Background: Airspace Dimensions Assessment with nanoparticles (AiDA) is a new method for non-invasive measurement of pulmonary distal airspaces. The aim of this study was to compare AiDA measurements with other pulmonary function variables to better understand the potential of AiDA in a clinical context. Methods: AiDA measurements and pulmonary function tests were performed in 695 subjects as part

MetaDL : Declarative program analysis for the masses

While Datalog provides a high-level language for expressing static program analyses, it depends on external tooling to extract the input facts from the analyzed programs. To remove this dependency, we present MetaDL. The MetaDL system consists of a Datalog language extension for source-level program analysis and tools for generating the language extension from a description of the analyzed languag

Inhibition of epileptiform activity by neuropeptide Y in brain tissue from drug-resistant temporal lobe epilepsy patients

In epilepsy patients, drug-resistant seizures often originate in one of the temporal lobes. In selected cases, when certain requirements are met, this area is surgically resected for therapeutic reasons. We kept the resected tissue slices alive in vitro for 48 h to create a platform for testing a novel treatment strategy based on neuropeptide Y (NPY) against drug-resistant epilepsy. We demonstrate

Improvement in indices of cellular protection after psychological treatment for social anxiety disorder

Telomere attrition is a hallmark of cellular aging and shorter telomeres have been reported in mood and anxiety disorders. Telomere shortening is counteracted by the enzyme telomerase and cellular protection is also provided by the antioxidant enzyme glutathione peroxidase (GPx). Here, telomerase, GPx, and telomeres were investigated in 46 social anxiety disorder (SAD) patients in a within-subject