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Investigation of heat transfer and fluid flow in fractal truncated ribbed channels for the internal cooling of turbine blades

Ribs are widely employed in internal cooling passages of turbine blades to enhance heat transfer. From the mathematics, a fractal is an abstract object used to describe naturally occurring objects which exhibits similar properties with increased smaller scales. In a ribbed channel, originating from two sides truncated ribs, fractal truncated ribs are built and the evolving process contains three s

Experimental investigation of heat transfer enhancement on the endwall around an obstacle embedded with a vortex generator pair

Heat transfer enhancement on the endwall around an obstacle embedded with a pair of vortex generators is investigated. Obstacles with cylindrical and square cross sections are experimentally examined and compared with and without vortex generators. The vortex generators employed is a pair of longitudinal winglet vortex generator. Local Nusselt numbers are calculated for both types of obstacles in

Enhancement of HFE-7200 pool boiling heat transfer on copper surfaces with nanoparticle coatings

Saturated pool boiling heat transfer of HFE-7200 is investigated experimentally on copper surfaces with nanoparticle coatings at atmospheric pressure. The coatings are generated by an electrophoretic deposition method. Two modified surfaces are prepared with Cu-Zinc nanoparticles of 0.3 mg and 0.6 mg, respectively. During the deposition, ethanol works as the solvent while the electrical potential

Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes

Genetic studies promise to provide insight into the molecular mechanisms underlying type 2 diabetes (T2D). Variants associated with T2D are often located in tissue-specific enhancer clusters or super-enhancers. So far, such domains have been defined through clustering of enhancers in linear genome maps rather than in three-dimensional (3D) space. Furthermore, their target genes are often unknown.

A matrix weighted bilinear Carleson lemma and maximal function

We prove a bilinear Carleson embedding theorem with matrix weight and scalar measure. In the scalar case, this becomes exactly the well known weighted bilinear Carleson embedding theorem. Although only allowing scalar Carleson measures, it is to date the only extension to the bilinear setting of the recent Carleson embedding theorem by Culiuc and Treil that features a matrix Carleson measure and a

Informal caregivers in stroke : Life impact, support, and psychological well-being—A Swedish Stroke Register (Riksstroke) study

Background: Informal caregivers provide a large amount of day-to-day assistance and are crucial for the ability of survivors to recover and adapt to life after stroke. Aim: The development of caregiver support programs is limited by lack of large long-term follow-up studies. We present a comprehensive study of Swedish stroke caregivers' life situation in relation to degree of functional dependency

In-season plot area loss and implications for yield estimation in smallholder rainfed farming systems at the village level in Sub-Saharan Africa

The shortfalls in the quality, quantity, and reliability of agriculture performance data are neither new nor confined to Sub-Saharan Africa (SSA). It is, however, a more dire challenge given the overwhelming importance of agriculture in the economies of most countries in the region in terms of food security and poverty reduction. While farmers’ self-reported (SR) data on crop outputs and farm size

Protein Structure Classification and Loop Modeling Using Multiple Ramachandran Distributions

Recently, the study of protein structures using angular representations has attracted much attention among structural biologists. The main challenge is how to efficiently model the continuous conformational space of the protein structures based on the differences and similarities between different Ramachandran plots. Despite the presence of statistical methods for modeling angular data of proteins

Aeration rate effect on the growth kinetics, phytase production and plasmid stability of recombinant Escherichia coli BL21 (DE3)

Phytase production using Escherichia coli BL21 (DE3), a recombinant strain harboring a plasmid encoding thermostable Bacillus phytase, in semi-industrial scale was studied in this work. Among the factors needed to be considered in order to achieve high enzyme yield, aeration rate plays an important role. Suitable aeration is required to supply cells with sufficient amount of air for cell and phyta

Protein separation using metal ion-bound particles in aqueous two-phase system

Metal ion affinity partitioning of protein in aqueous two-phase systems was studied using Sepharose as ligand carrier as an integrated adsorption partitioning. Cu(II)-bound Sepharose was mixed with protein solution and an aqueous two-phase system. The affinity sorbent was distributed quantitatively to the upper side or the interface. The binding studies of lysozyme to copper-bound gel in PEG/dextr

Primary fatty amides are potential plasma biomarkers for AD

A new study has found that levels of primary fatty amides in plasma correlate with amyloid-β pathology and other Alzheimer disease (AD)-related phenomena. In addition to identifying potential plasma biomarkers for AD, the findings suggest new avenues for investigation into the early stages of AD.

Increased Intracranial Pressure Attenuates the Pulsating Component of Cerebral Venous Outflow

Background: The underlying physiology of the intracranial pressure (ICP) curve morphology is still poorly understood. If this physiology is explained it could be possible to extract clinically relevant information from the ICP curve. The venous outflow from the cranial cavity is pulsatile, and in theory the pulsatile component of venous outflow from the cranial cavity should be attenuated with inc

HLA-DRB3*01:01 exhibits a dose-dependent impact on HPA-1a antibody levels in HPA-1a–immunized women

HLA-DRB3*01:01 is a predisposing factor for human platelet antigen 1a (HPA-1a) immunization, which is responsible for most cases of fetal and neonatal alloimmune thrombocytopenia. The aim of this study was to investigate if the HLA-DRB3*01:01 allele imposes a dose-dependent effect on anti-HPA-1a levels and neonatal platelet counts. One hundred and thirty HPA-1a–immunized women were divided into 3

The Gaia-ESO Survey : The inner disc, intermediate-Age open cluster Pismis 18

Context. Pismis 18 is a moderately populated, intermediate-Age open cluster located within the solar circle at a Galactocentric distance of about seven kpc. Few open clusters have been studied in detail in the inner disc region before the Gaia-ESO Survey. Aims. New data from the Gaia-ESO Survey allowed us to conduct an extended radial velocity membership study as well as spectroscopic metallicity

Oscillatory migration of accreting protoplanets driven by a 3D distortion of the gas flow

Context. The dynamics of a low-mass protoplanet accreting solids is influenced by the heating torque, which was found to suppress inward migration in protoplanetary disks with constant opacities. Aims. We investigate the differences in the heating torque between disks with constant and temperature-dependent opacities. Methods. Interactions of a super-Earth-sized protoplanet with the gas disk are e

Social skills training for attention deficit hyperactivity disorder (ADHD) in children aged 5 to 18 years

Background: Attention deficit hyperactivity disorder (ADHD) in children is associated with hyperactivity and impulsivity, attention problems, and difficulties with social interactions. Pharmacological treatment may alleviate the symptoms of ADHD but this rarely solves difficulties with social interactions. Children with ADHD may benefit from interventions designed to improve their social skills.We