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Maf transcription factors have pivotal roles in regulating beta cell function and development, and loss of MafA expression has been associated in inducing pro-inflammatory gene signature. This study assessed if the loss of MafA transcription factor expression contributes to the development of islet inflammation. Immunohistochemical analysis showed that 8 months old MafA deficient pancreata (MafA-/
Scholars discuss about the importance of processes of communication in which all stakeholders actively participate influencing the constitution and development of change and organizations. However, communication professionals struggle to em-brace these assumptions and modify their roles and practices in these complex set-tings. This study aims to understand how practitioners adapt their roles in t
Detta examensarbete behandlar en energieffektivisering av Örebrogatan 2A-C i Kv. Hallonet som Helsingborgshem äger och förvaltar. Genom att ge förslag på olika åtgärder för att få en sänkt energianvändning på den idag energislukande byggnaden är förhoppningen att arbetet ska kunna användas som underlag i en framtida renovering av byggnaden. Byggnaden från 1954 består idag av 20 lägenheter fördeladThis thesis is about an energy efficiency improvement of Örebrogatan 2 in Kv. Hallonet that Helsingborgshem owns and manages. By giving suggestions for different actions to get a reduced energy consumption on the today energy-wasteful building is the hope that the work and the conclusions can be used for a future renovation of the building. Whilst Sweden is growing with many new buildings, there a
I Peru påverkas beslutet att utbilda sig på eftergymnasial nivå, för både män och kvinnor, i hög grad av familjen. Särskilt på landsbygden är ojämlikheten hög, där kvinnor i mycket högre utsträckningen än män tenderar att inte vidareutbilda sig. Syftet med denna studie var därmed att undersöka hur föräldrastöd angående döttrars eftergymnasiala utbildning påverkas av tre variabler, baserade på sociIn Peru, the decision of pursuing higher education for boys and girls is dependent on one’s family. Especially in rural areas, the inequalities are high and girls are far less likely than boys to attend post-secondary education. Therefore, this study explored how parental support in relation to one’s daughter’s post-secondary education is influenced by three variables, based on the social cognitiv
Den mekansika konstruktionen av en baklucka till en bil är relativt enkel. Bakluckan roterar kring sina gångjärn likt en pendel och hålls antingen stängd eller öppen. När bakluckan hålls öppen görs detta normalt med hjälp av gasfjädrar. Detta examensarbetet har behandlat situationen då bakluckan är så stor och gasfjädern så stark så att resten av fordonet blir synligt påverkad av kraften som dessaThe purpose of this thesis is to analyze the construction of a hearse made by Adiga on account for Nilsson Special Vehicles, NSV. The vehicle suffers from deformations in the rear as a result of mismatched gas springs and in side doors when these are kept open. Virtual models of side doors and rear are prepared in Catia and then analyzed in Ansys. For the tailgate, the minimum necessary force in
I denna uppsats står rädsla för att tala i fokus. Talrädsla belyses med retorikämnet som grund, och studien tar avstamp i den svenska gymnasieskolan. Syftet med studien är att ta fram ett handfast material för hur svensklärare på gymnasieskolan kan arbeta med talrädda elever. För att uppnå syftet genomförs en litteraturstudie, där handböcker som behandlar området talrädsla studeras. I dessa handböIn this study, language anxiety is in focus. Language anxiety is studied with the subject of rhetoric as a basis, and the study is based on the Swedish upper secondary school. The aim of the study is to produce a solid material for how Swedish teachers at upper secondary school can work with students with language anxiety. In order to achieve this purpose, a literature study is carried out, in whi
Purpose: The purpose of this thesis is to fill the existing research gap in Europe by examining the effect of corporate social performance (CSP) on firms’ credit ratings. Methodology: Through a quantitative research strategy, we examine the relationship between CSP and firms’ credit rating using a fixed effects regressions analysis based on a panel data set. Theoretical perspectives: The theor
Brain drain refers to the international migration of highly skilled people. It can affect countries of all development levels, but it is the brain drain from developing countries that has garnered the most attention. There are two purposes with this study, the first is to find the relationship between brain drain and unemployment, GNI per capita and political stability. The second purpose is to se
Title: The Driving Force of Sustainability - A Case Study of Brinova Fastigheter AB Seminar date: 2019-06-05 Course: FEKH19 Business Administration: Bachelor Degree Project in Strategic Management Undergraduate Level Authors: Martin Frankendal, Valdemar Lennartsson & Eric Witt Advisor: Devrim Göktepe-Hultén Purpose: The purpose of this study is to examine which the driving forces are to implem
Today, the public of society is considered to obsess of the topic of crime which daily news frequently distributes to the public by proclaiming shockingly headline regarding criminals and deviance. All tough, it seems to be an asymmetry between the public perception of crime and the characteristics of suspects versus the court's judgment of crime and the characteristics of suspects. This asymm
Kroppens största organ utgörs av huden, en töjbar och mjuk vävnad vars viktigaste uppgift är att skydda oss från omvärlden. Hudens yttersta lager, hornlagret eller Stratum Corneum på latin, utgör den viktigaste barriären mot yttre fiender som skadliga virus, bakterier och giftiga kemikalier. Hornlagrets barriäregenskaper beror på dess sammansättning och uppbyggnad, som kan liknas med en tegelstensStratum corneum (SC) is the outer most layer of the epidermis recognized as the main barrier of the skin. The most important function of SC is to regulate water loss to the outer environment and prevent the chemical as well as microbial invasion. This exceptional ability of SC is attributed to its composition and architecture which resembles an actual brick and mortar wall. The structure and compo
Mexico has a large share of indigenous people that are living in disproportionally high poverty levels. As a result, rural communities are facing deprivation of indigenous peoples in search of work in urban areas. The community-based cooperative “Millennial Women” was formed about 2-3 years ago with the intentions to maintain community resilience while promoting economic development in the rural c
Paris is built upon an almost 300-kilometre long quarries network which reflects a part of the city’s history. While the access to most parts of it is forbidden due to its hazard, this underground network attracts many illegal visitors called Cataphiles. This research aims to investigate the risks threatening illegal visitors and those affecting the heritage of the catacombs. In order to get an ov
A great number of cotton swabs from crime scenes are sent to the Swedish National Forensic Center each year for analyzation of DNA. Many of the swabs contain small amounts of cells and therefore it’s important to optimize the sampling of cells and the extraction of DNA. This would make more samples useful for DNA profiling and possibly be used as evidence. Today, a large amount of cotton, to wher
The purpose of this study is to unveil the determinants of value creation in supply chains and analyse the role of blockchain in this ecosystem. The study follows a qualitative research design through a case study, focusing on the dairy industry in Western Europe. The main theoretical perspectives are Transaction Cost Econonomics and Value Creation, combined with blockchain literature in supply ch
Denna kvalitativa intervjustudie undersöker politiskt arbete utfört av personer som upplever attraktion till fler än ett kön, inom organisationer eller kontexter som arbetar för HBTQ-frågor. Studiens syfte är för det första att undersöka hur politiskt arbete förstås av personer som utför det. För det andra är syftet med studien att bidra till forskningen om personer som upplever attraktion till flThis qualitative interview study explores political work by people who are at-tracted to more than one gender, within organisations or contexts that are en-gaging with LGBTQ-rights. The first purpose of the study is to gain understand-ing about how working for a political struggle is perceived by people, the second purpose is to add to the research about people that are experiencing attraction to
Transportation plays an essential role in the European economy. The European Transport Policy aims to establish a sustainable means of transportation system to provide the social, economic and environmental needs of society contributing to an integrated society. Major reasons for people to choose private cars over public transport are infrequent connections, inadequate infrastructure and low therm
Det finns mycket lite forskning om hur olika organisationsmodeller för nyanländas undervisning faktiskt fungerar. Därför har målet i den här uppsatsen varit att lyfta fem olika lärares uppfattningar om hur organisationen för nyanländas undervisning fungerar på deras skolor. Datainsamlingen har skett genom intervjuer. Lärare från olika delar av Sverige som arbetar på olika skolor med olika typer av
In water resource management, it is of importance to be able to predict how different activities might contaminate aquifers. For this kind of application, numerical modelling of water and solute transport can be a useful tool. The purpose of this study was to investigate if one-dimensional numerical modelling (Hydrus-1D) of water in the unsaturated zone of the subsoil is useful to assess the trans
Syfte: Syftet är att utreda hur going-concern varningar och andra faktorer påverkar storbankernas kreditgivningsbeslut och varför det finns likheter och skillnader storbankerna emellan. Metod: Semistrukturerade intervjuer med företagsrådgivare från tre storbanker i Sverige. Teoretiska perspektiv: Uppsatsens frågeställningar besvaras med hjälp av institutionell teori. Denna teorin syftar till att
