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Background: Single diffusion encoding is a widely used, noninvasive technique for probing the tissue microstructure in breast tumors. However, it does not provide detailed information about the microenvironmental complexity. This study investigated the clinical utility of tensor-valued diffusion encoding for evaluating microstructural changes in breast cancer after neoadjuvant chemotherapy (NAC).

The vast majority of pituitary neuroendocrine tumors (PitNETs) are benign and slow growing with a low relapse rate over many years after surgical resection. However, about 40% are locally invasive and may not be surgically cured, and about one percentage demonstrate an aggressive clinical behavior. Exceptionally, these aggressive tumors may metastasize outside the sellar region to the central nerv

Size-controlled monodisperse droplets are indispensable in food, cosmetics, and healthcare industries. Although emulsion formation from bulk phases is well-explored, a robust in situ method to continuously reform existing emulsions is unavailable. Remarkably, we introduce a continuous flow acousto-microfluidics technique which enables simultaneous trapping-coalescence-splitting of droplets to refo

Background: Optimal anticoagulation management in patients with myeloproliferative neoplasms (MPN) experiencing splanchnic vein thrombosis (SpVT) requires balancing risks of bleeding and recurrent thrombosis. Objectives: We conducted a systematic review and meta-analysis to assess the incidence of bleeding and thrombosis recurrence in patients with MPN-SpVT. Methods: We included retrospective or p

Chromosomal aneuploidy, that is, numerical chromosome aberrations, is one of the molecular hallmarks of cancer. However, when neoplasms are studied with sequencing- and array-based approaches, chromosome numbers and ploidy states are typically inferred from bulk DNA data. Furthermore, published molecular estimates of neoplasia-associated aneuploidy often also include genomic imbalances resulting f

Schlieren imaging has been established as a reliable optical measurement technique for flame visualizations and retrieval of laminar burning velocity information. However, it is off limited capability and adaptability due to the optical configuration of a conventional Schlieren setup. In this regard, background oriented Schlieren (BOS) provides a unique opportunity to quantitatively characterize d

The TFM-DYN model represents a significant advancement from static flow accumulation estimations into dynamic hydrological modeling (Nilsson et al., 2021). It incorporates variable precipitation in time and space as input together with high-resolution topography and includes functions for friction and infiltration to produce results such as water depths, flow velocity, inundated areas, flow pathwa

This open access book explores how to build a gender-just peace in which women’s political citizenship is foregrounded through a case study of Northern Ireland. It addresses the role that civil society can play in peacebuilding and in political life in deeply divided transitional societies. It specifically focuses on women’s groups, and, as such, studies what grassroots peacebuilding across an eth

We present a protocol for the Boolean matrix product of two n×n Boolean matrices on the congested clique designed for the situation when the rows of the first matrix or the columns of the second matrix are highly clustered in the space {0,1}n. With high probability (w.h.p), it uses O~Mn+1 rounds on the congested clique with n nodes, where M is the minimum of the cost of a minimum spanning tree (MS

Semi-arid ecosystems, common across the Australian continent, strongly influence the inter-annual variability and trend in the global terrestrial net carbon sink. Here we explore the future Australian terrestrial carbon cycle using the CMIP6 ensemble, and the dynamic global vegetation model LPJ-GUESS. Uncertainty in Australia's carbon storage in vegetation ranged between 6 and 49 PgC at the end of

Background & objectives: Endoscopy is the current gold standard for evaluation of disease activity in ulcerative colitis. The Mayo Endoscopic Subscore (MES) is commonly used for quantifying disease activity, but it has several weaknesses. Numerous new endoscopic indices have been developed but none of these have been widely implemented, likely due to limited feasibility. The primary objective

Background: Family-centered rounds (FCR) reduce the risk of psychological comorbidities of family members and improve the quality of communication between providers and families. Materials and methods: We conducted a pilot quality improvement study analyzing family perceptions of virtual FCR. Family members of previously admitted cardiac ICU patients who participated in at least one session of vir

This paper reviews research on child L2 French (cL2) published since 2000 with a focus on research areas and methodology in a broad sense. The aim of the review is to identify methodological trends in the research, to exemplify, and to provide a discussion of prominent features. The review shows that research on cL2 French has mainly focused on the acquisition of morphosyntax based on oral product

The article analyzes power structures and relations in the Soviet Union in the mid-1960s, i.e., in the first years of Leonid Brezhnev's rule. It shows how Brezhnev limited the control mechanisms of power introduced by Nikita Khrushchev in order to consolidate his own position. The analysis contributes to a better understanding of the failure of Khrushchev's "reform communism" and the construction

Commercial small-scale fisheries along the Baltic Sea coasts have declined over the years although these fisheries are viewed as important for coastal development and food security at the local, national, and EU levels. The viability and future of small-scale fisheries are severely challenged by problems caused by grey seals. The conflict, occurring between Baltic Sea coastal fisheries and conserv

This work aimed to investigate structurally defined biobased polymers as non-leachable and non-toxic UV blockers for sunscreen applications. Two dicarboxylate monomers were synthesized using two lignin-based monomeric aromatic compounds, vanillin and 4-hydroxybenzaldehyde. These two monomers were then polymerized together with linear aliphatic diols of varying lengths to produce UV-active polyeste

Eye tracking technology has become increasingly prevalent in scientific research, offering unique insights into oculomotor and cognitive processes. The present article explores the relationship between scientific theory, the research question, and the use of eye-tracking technology. It aims to guide readers in determining if eye tracking is suitable for their studies and how to formulate relevant