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Transfusion-related acute lung injury (TRALI) is a syndrome of respiratory distress upon blood transfusion and is the leading cause of transfusion-related fatalities. Whether the gut microbiota plays any role in the development of TRALI is currently unknown. We observed that untreated barrier-free (BF) mice suffered from severe antibody-mediated acute lung injury, whereas the more sterile housed s

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Sustainable Drainage Systems (SuDS) can be considered the joint product of water engineering and urban planning and design since these systems must comply with hydraulic, hydrologic, and social-ecological functions. To enhance this joint collaboration, a conceptual model of mesoscale SuDS is introduced based on the observed rainfall-runoff responses from two catchments with SuDS and a pipe-bound c

Detta kapitel handlar om ersättningsmodellens betydelse inom sjukhusvårdeni Region Skåne. År 2012 återgick regionen till traditionellanslagsfinansiering efter att under perioden 2006–2011 ersatt sjukhuseni efterskott utifrån antalet producerade vårdkontakter; så kalladDRG-baserad ersättning.DRG-baserad ersättning har stått i centrum för kritiken mot NewPublic Management inom sjukhusvården. Såväl f

The clichéd conceptualization of cancer illness as a battle, which the patient can either win or lose, can be problematic. For patients referred to palliative care, it can cause feelings of guilt and failure. This framing of cancer, here referred to as ‘the battle script’, has been questioned in previous research, and there seems to be awareness among health practitioners that battle metaphors shoThe clichéd conceptualization of cancer illness as a battle, which the patient can either win or lose, can be problematic. For patients referred to palliative care, it can cause feelings of guilt and failure. This framing of cancer, here referred to as ‘the battle script’, has been questioned in previous research, and there seems to be awareness among health practitioners that battle metaphors sho

This chapter discusses fundamental considerations related to the measurement of knowledge of multiword items (MWI). Central concepts like validity and reliability are accounted for, as are steps for linking theoretical and operational definitions with scoring procedures. Next, different approaches for MWI measurement are presented. This includes an account of traditional pencil-and-paper test form

Aim: To determine if age is a factor influencing the type of breast cancer surgery (radical versus conservative) in Italy and to investigate the regional differences in breast cancer surgery clinical practice. Methods: Retrospective study is based on national hospital discharge records. The study draws on routinely collected data from hospital discharge records in Italy in 2010. The following excl

INTRODUCTION: Administrative healthcare databases are useful to investigate the epidemiology, health outcomes, quality indicators and healthcare utilisation concerning peptic ulcers and gastrointestinal bleeding, but the databases need to be validated in order to be a reliable source for research. The aim of this protocol is to perform the first systematic review of studies reporting the validatio

Background: The epidemic of Alzheimer's disease (AD) represents a significant challenge for the health care and social service systems of many developed countries. AD affects both patients and family caregivers, on whom the main burden of care falls, putting them at higher risk of stress, anxiety, mortality and lower quality of life. Evidence remains controversial concerning the effectiveness of p