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Human-bacterial interactions play a crucial role in several essential aspects of life. Here, we describe how a secreted protein from the skin commensal Cutibacterium acnes, RoxP, functions as a sacrificial redox effector molecule that facilitates beneficial interactions with its human host by counteracting oxidative stress and reducing stress-induced inflammation. Using a combination of structural

Time-frequency (TF) postprocessing methods are often used to form concentrated TF representations (TFRs) for nonstationary signals. Regrettably, most such techniques are sensitive to noise and tend to underestimate weak components when dealing with transient signals, resulting in sidelobes and low-resolution TFRs. In this work, we introduce a generalized group delay (GD) weighted sparse TF (GWSTF)

Background: Ultrafiltration (UF) insufficiency in peritoneal dialysis (PD) often leads to transfer to hemodialysis. Therefore, strategies to prolong time on therapy are needed. The use of a combined crystalloid and colloid solution, also called bimodal PD, can help improve UF. Methods: We propose a method for reconstituting bimodal solutions. Three bimodal PD solutions, with respectively 100 ml (s

The solute exclusion technique (SET) is often used to characterise the nano-porous structure of water-swollen cell walls. SET is based on the immersion of water-saturated wood samples in solutions of probe molecules of known size. Based on determined concentration differences in the solution before and after immersion, the accessible water within the wood is determined for each probe. However, thi

The Swedish Radiation Safety Authority has presented a report on severe accident scenarios at the European Spallation Source (ESS) for dimensioning the emergency preparedness zones around the facility. The source-term in the scenario consisted of more than 80 tungsten-target spallation products with physical half-life (T½) exceeding 1 hour. The purpose of this study is to establish which of these

The European Health Data Space (EHDS) marks a pivotal moment in regulating wellness applications within the European Union. This chapter examines the implications of the EHDS for user control over electronic health data processed through wellness apps, scrutinising the regulatory frameworks provided by both the General Data Protection Regulation (GDPR) and the EHDS. Despite the GDPR’s stringent re

En vetenskaplig text i vilken jag på engelska och för en internationell läsarkrets presenterar de centrala forskningsresultaten och slutsatserna från min avhandling.

17 kap. 3 § rättegångsbalken (RB) omgärdas av omfattande begrepps- och teoribildning. Som exempel har det skrivit tre svenska avhandlingar som har bestämmelsen som huvudtema. När det kommer skiljeförfaranden enligt lagen (1999:116) om skiljeförfarande (LSF) är det en omdebatterad fråga i vad mån tvistemålsprocessens begrepps- och teoribildning bör tillämpas analogt. LSF har ingen uttrycklig bestäm

Samples of Fucus serratus and Fucus vesiculosus have been regularly collected at Särdal (56.76 N, 12.63E) on the Swedish west coast since 1967, for most of the time, every two months. In 2020, sampling of Fucus spp. was extended to 44 other locations along the Swedish west, south, and east coast for comparison with Särdal data. At seven of these locations, water samples and extra samples of Fucus

In contemporary architectural research and practice, a critique from alternative positions has often been incorporated through situated perspectives from recipients of architectural acts. The text aims to discuss immediate situated impressions from recipients of architectural acts as well as architects’ reading of circumstances.

A review of Tart's contribution to various vields

Background: Cancer care for individuals with intellectual disabilities (ID) is challenging, with evidence of disparities, late diagnoses, and overlooked experiences of the individuals in question.Aim: To explore how individuals with concomitant ID and cancer experience the illness and navigate cancer care trajectories and everyday life from perspectives of themselves, their relatives and professio

The observation of the electroweak production of a W boson and a photon in association with two jets, using pp collision data at the Large Hadron Collider at a centre of mass energy of s=13 TeV, is reported. The data were recorded by the ATLAS experiment from 2015 to 2018 and correspond to an integrated luminosity of 140 fb-1. This process is sensitive to the quartic gauge boson couplings via the

Fungi are one of the most diverse groups of organisms with an estimated number of species in the range of 2–3 million. The higher-level ranking of fungi has been discussed in the framework of molecular phylogenetics since Hibbett et al., and the definition and the higher ranks (e.g., phyla) of the ‘true fungi’ have been revised in several subsequent publications. Rapid accumulation of novel genomi

In the present work, we addressed the relationship between parental leave policies and social norms. Using a pre-registered, cross-national approach, we examined the relationship between parental leave policies and the perception of social norms for the gender division of childcare. In this study, 19,259 students (11,924 women) from 48 countries indicated the degree to which they believe childcare

Structural proteomics has undergone a profound transformation, driven by the convergence of advanced experimental methodologies and computational innovations. Cutting-edge mass spectrometry (MS)-based approaches, including cross-linking MS (XL-MS), hydrogen-deuterium exchange MS (HDX-MS), and limited proteolysis MS (LiP-MS), now enable unprecedented insights into protein topology, conformational d