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Recent decades have seen much interest in racial and ethnic differences in drug response. The most emblematic example is the heart drug BiDil, approved by the US Food and Drug Administration in 2005 for “self-identified blacks.” Previous social science research has explored this “racialization of pharmaceutical regulation” in the USA, and discussed its implications for the “pharmaceuticalization o

Svar till flera insändare som varit kritiska på "Min mening" till bekämpningen av vresrosor utmed Helsingborgs kust.

This essay explores discourses on American quality serial television in Sweden’s leading newspapers, and how a gradual discursive repositioning of quality TV – from the extraordinary to the everyday – is linked to Swedish television’s transition into a screen culture increasingly dominated by commercial streaming services. The analysis of the newspaper material shows that the campaign to legitimat

Det finns en uttalad politisk vilja att stödja det lokala fisket i Sverige. Ett skäl till detta är att levande fiskehamnar kan locka turister till kustnära samhällen. I denna studie analyserar vi kopplingen mellanyrkesfiske och antalet gästnätter på hotell, vandrarhem och stugbyar.* Vi finner att antalet gästnätter är högre i kustkommuner med mer yrkesfiske.* Vi finner däremot inte stöd för att yr

Tendons fulfill an important musculoskeletal function by enabling energy-efficient force transmission between muscles and bones. The tendon is a collagen-rich connective tissue that adapts to mechanical loading through mechanobiological processes. The tendon contains a hierarchical collagen fiber structure that displays complex mechanical behaviour by storing and dissipating energy. Current unders

I avhandlingen skildras vardagslivet hos en grupp unga som bor på landsbygden. Medan vardagen i regel ses som grå och trist visar avhandlingen hur unga gör den till något särskilt, meningsfullt och roligt, hur de gör förhöjd vardaglighet. Genom att studera ungas vardagsliv med etnografiska metoder och teoretisk nyfikenhet når studien kunskap bortom de problembeskrivningar som vanligtvis skildrar sToday, the terms ‘young people’ and ‘rural Sweden’ are automatically associated with problems. Young people are associated with various worrying issues, such as mental illness, stress, pressure at school, or internet risk. Being young and living in a rural community is often regarded as especially problematic. Rural life is thought dull, and bracketed with isolation, lack of meaningful activities,

Background: Sepsis is a critical illness with high morbidity and mortality rates. Each year, sepsis affects about 48.9 million people all over the world. This study aims to illuminate how sepsis survivors experience sepsis and the impact of sepsis, as well as the health-related quality of life thereafter. Methods: An interview study with eight sepsis survivors was carried out in Sweden with an ind

The stability of nanoparticles and their supports are critical, but poorly understood, parameters for applications of such systems in liquid environments. Here we develop an approach to systematically investigate the stability of aerosol-generated nanoparticles after exposure to commonly used solvents using a combination of identical location-SEM and density/size analysis. We demonstrate that the

OBJECTIVES: To evaluate incidence of self-reported falls and associated factors in a ten-year perspective after stroke.METHODS: From a population-based cohort of first-ever stroke patients (n = 416) included in the Lund Stroke Register between March 1, 2001, and February 28, 2002, we performed a follow up of all 145 survivors ten years after stroke. We collected data on age, gender, main stroke ty

Atherosclerotic plaques are characterized by an accumulation and subsequent oxidation of LDL, resulting in adaptive immune responses against formed or exposed neoepitopes of the LDL particle. Autoantibodies against native p210, the 3136–3155 amino acid sequence of the LDL protein apolipoprotein B-100 (apoB100) are common in humans and have been associated with less severe atherosclerosis and decre

Methotrexate (MTX) impairs antibody response after pneumococcal vaccination. We aimed to investigate differences in phenotypes of circulating B and T cells after pneumococcal conjugate vaccine (PCV) in rheumatoid arthritis (RA) patients on MTX (MTX group), RA without disease-modifying drugs (0DMARD), and controls (HC). MTX group (n = 11), 0DMARD (n = 12) and HC (n = 13) were studied. Blood samples

This report presents the results of sediment sampling in Rönne å (river) at Ängelholm, located in the north-western part of Scania, which is the southern-most province in Sweden. The sampling and subsequent grain-size analysis were performed primarily to verify hypotheses about main mechanisms controlling local scour at a number of sites where scour holes had been observed in the river during deta

In its most recent Energy Union package, the European Union puts citizens at the core of the cleanenergy transitions. Beyond policy, disruptive innovations in energy sectors are challenging thetraditional business model of large energy utilities. One such disruptive, social innovation is theemergence of new clean energy communities (“NEWCOMERS”).The possible benefits of these “NEWCOMERS” for their

The strength of Sen’s concept of poverty lies in the fact that it goes beyond the traditional concepts of poverty and is able to grasp the complexity of poverty. At the same time, the strength of Sen’s concept of poverty is also its weakness. It is very abstract indeed. Income does not tell us much about poverty according to the capability deprivation approach since poverty is more than being shor

Dimethyl sulfide (DMS) is produced by plankton in oceans and constitutes the largest natural emission of sulfur to the atmosphere. In this work, we examine new particle formation from the primary pathway of oxidation of gas-phase DMS by OH radicals. We particularly focus on particle growth and mass yield as studied experimentally under dry conditions using the atmospheric simulation chamber AURA.

Background: Group B Streptococcus (GBS) is the leading cause of life-threatening infections in new-borns and may cause invasive disease, stillbirth and preterm delivery during pregnancy. While no licensed vaccine exists, maternal immunization might protect against neonatal disease and adverse pregnancy outcomes. We assessed the safety and immunogenicity of a prototype vaccine consisting of the fus

Hematopoietic stem cells (HSCs) are typically characterized by transplantation into irradiated hosts in a highly perturbed microenvironment. Here, we show that selective and temporally controlled depletion of resident HSCs through genetic deletion of Gata2 constitutes efficient recipient conditioning for transplantation without irradiation. Strikingly, we achieved robust engraftment of donor HSCs