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Background: The global community has committed to achieving universal access to sexual and reproductive health and rights (SRHR) services, but how to do it remains a challenge in many low-income countries. Capacity development is listed as a means of implementation for Agenda 2030. Although it has been a major element in international development cooperation, including SRHR, its effectiveness and

The Cherenkov Telescope Array (CTA) is a next generation ground-based very-high-energy gamma-ray observatory that will allow for observations in the >10 GeV range with unprecedented photon statistics and sensitivity. This will enable the investigation of the yet-marginally explored physics of short-time-scale transient events. CTA will thus become an invaluable instrument for the study of the phys

Tenosynovial giant cell tumour (TGCT) is a rare, locally aggressive, mesenchymal tumor arising from the joints, bursa and tendon sheaths. TGCT comprises a nodular- and a diffuse-type, with the former exhibiting mostly indolent course and the latter a locally aggressive behavior. Although usually not life-threatening, TGCT may cause chronic pain and adversely impact function and quality of life (Qo

In these proceedings we summarize the current status of the study of the sensitivity of the Cherenkov Telescope Array (CTA) to detect diffuse gamma-ray emission from the Perseus galaxy cluster. Gamma-ray emission is expected in galaxy clusters both from interactions of cosmic rays (CR) with the intra-cluster medium, or as a product of annihilation or decay of dark matter (DM) particles in case the

Laboratory and animal research support a protective role for vitamin D in breast carcinogenesis, but epidemiologic studies have been inconclusive. To examine comprehensively the relationship of circulating 25-hydroxyvitamin D [25(OH)D] to subsequent breast cancer incidence, we harmonized and pooled participant-level data from 10 U.S. and 7 European prospective cohorts. Included were 10,484 invasiv

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Structural changes and neuropathology in the hypothalamus have been suggested to contribute to the non-motor manifestations of Huntington's disease (HD), a neurodegenerative disorder caused by an expanded cytosine-adenine-guanine (CAG) repeat in the huntingtin (HTT) gene. In this study, we investigated whether hypothalamic HTT expression causes transcriptional changes. Hypothalamic RNA was isolate

Expanded CAG repeats lead to debilitating neurodegenerative disorders characterized by aggregation of proteins with expanded polyglutamine (polyQ) tracts. The mechanism of aggregation involves primary and secondary nucleation steps. We show how a noncanonical member of the DNAJ-chaperone family, DNAJB6, inhibits the conversion of soluble polyQ peptides into amyloid fibrils, in particular by suppre

Due to their efficiency, revitalized traditional techniques for irrigation management of scarce water resources have been suggested as a way to at least partially cope with the present water crises in the Middle East. A better irrigation management includes re-using treated wastewater in agriculture. Treated wastewater should also be used in industrial processes, thus contributing to a more effici

In the scope of a Swedish research project on expert knowledge as a basis for legal decisions, this article focuses on serious criminal cases. Using a model that describes rhetorical situations as well as empirical material based in 150 court decisions, the aim is to analyze the conditions surrounding the use of expert evidence in criminal law processes, to what extent and by whom such evidence is

Ecosystem-based adaptation (i.e. the use of ecosystem services to adapt to climate change) and its mainstreaming into municipal planning to foster sustainable transformation is receiving increasing interest from both academic and governmental bodies. However, little is known about the pathways for its systematic implementation, or the extent to which it is already mainstreamed in municipal plannin

Miljontals människor världen över arbetar som gatuförsäljare, utom räckhåll för lagen. Eftersom verksamheten ses som illegal lever försäljarna under ett ständigt hot om att avhysas och att få sina varor konfiskerad. Olika strategier för formalisering, det vill säga stegvis legalisering, förespråkas och tillämpas, av såväl internationella utvecklingsorganisationer som regeringar, för att stärka gatMillions of people worldwide work outside the law as street vendors in order to earn a living. However, they often work in fear of police evictions and confiscations since their work is in many places considered illegal. In this context, formalization (steps towards legalization) is often portrayed as a model for empowerment that allows poor street vendors to improve their well-being. Formalizatio