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Reconstructing the Younger Dryas ice dammed lake in the Baltic Basin: Bathymetry, area and volume

A digital 3D-reconstruction of the Baltic Ice Lake's (BIL) configuration during the termination of the Younger Dryas cold phase (ca. 11700 cal. yr BP) was compiled using a combined bathymetric-topographic Digital Terrain Model (DTM), Scandinavian ice sheet limits, Baltic Sea Holocene bottom sediment thickness information, and a paleoshoreline database maintained at the Lund University. The bathyme

Taxonomic distinctness and species richness as measures of functional structure in bird assemblages

Most traditional "biodiversity" indices have an uncertain ecological interpretation, unfavourable sampling properties, and excessive data requirements. A new index of taxonomic distinctness (the average evolutionary distance between species in an assemblage) has many advantages over traditional measures, but its ecological interpretation remains unclear. We used published behavioural species data

B1 Bradykinin Receptor Homo-oligomers in Receptor Cell Surface Expression and Signaling: Effects of Receptor Fragments.

The human B1 bradykinin receptor is an inducible and constitutively active G protein-coupled receptor that is involved in the inflammatory and pain responses to injury. Here, we investigated the role of B1 receptor homo-oligomerization in cell surface receptor expression. B1 receptors tagged with either the FLAG or hemagglutinin epitope were monitored immunologically and by radio-ligand binding, b

Head movement restriction and postural stability in patients with compensated unilateral vestibular loss

OBJECTIVE: To study whether restriction of head-neck movements improves postural performance in patients with compensated unilateral total vestibular loss. DESIGN: Randomized controlled experimental study. SETTING: Laboratory for clinical and experimental vestibular testing at a tertiary referral center. PATIENTS: Fifteen consecutive patients (seven men, eight women, mean age 53 years) at routine

On the Ga II and Ga III resonance lines and the implication for chemical stratification in HGMN stars

The gallium abundance in HgMn stars has been reported to be different for analyses conducted from spectral lines in the optical versus those from the ultraviolet. We pursue this ultraviolet-optical discrepancy from a line-blending perspective by investigating the Hubble Space Telescope (HST) Space Telescope Imaging Spectrograph (STIS) spectrum of the sharp-lined HgMn binary star chi Lup. Its galli

Myofibroblast accumulation correlates with the formation of fibrotic tissue in a rat air pouch model.

OBJECTIVE: The pathogenesis of arthritic joints involves cartilage degradation and pannus formation. It is well known that pannus influences the cartilage; however, the mechanism behind how the degrading cartilage interacts with pannus is not well known. To investigate this interplay, the expression of extracellular matrix (ECM) components in pannus and the degrading cartilage was analyzed. METHOD

Consequences of axillary recurrence after conservative breast surgery

Background: The aim was to study the incidence, time course and prognosis of patients who developed axillary recurrence after breast-conserving surgery, and to evaluate possible risk factors for axillary recurrence and prognostic factors after axillary recurrence. Methods: In a population-based cohort of 6613 women with invasive breast cancer who had breast-conserving surgery between 1981 and 1990

The risk associated with indwelling catheters in children with haemophilia.

Infections are the most frequent complications associated with the use of central venous lines (CVLs) in children with haemophilia. Several retrospective studies that include data from a substantial number of patients have reported approximately 0.2-0.3 infections per 1000 catheter-days (mainly Port-A-Cath). Some studies have shown a much higher frequency of infections, 1-2/1000 catheter-days. The

Internationalisation in the Swedish nurse education from the perspective of teachers involved: An interview study

This paper presents results from an interview investigation with teachers in Swedish nurse education especially interested in internationalising the education. The aim has been to study teachers' understandings and experiences of internationalisation against the backdrop of the strong concern for internationalisation expressed in policy documents. The results are seen in the context of globalisati

2,2 '-nitrophenylisatogen potentiates P2X(1) receptor mediated vascular contraction and blood pressure elevation

The objective of this research was to examine the effects of chemical compounds with possible P2 receptor modulating effects and to characterize the potentiating effects of 2,2'-nitrophenylisatogen (NPI) on P2X(1) receptors in vitro and in vivo. Chemical compounds were tested in an in vitro pharmacological assay using vascular segments from the rat mesenteric artery stimulated by P2 receptor-speci

Interactions between charged surfaces immersed in a polyelectrolyte solution

With grand canonical simulations invoking a configurationally weighted scheme, we have calculated interactions between charged surfaces immersed in a polyelectrolyte, solution. In contrast to previous simulations of such systems, we have imposed full equilibrium conditions (i.e., we have included diffusive equilibrium with a bulk solution). This has a profound impact on the resulting interactions:

The feasibility of left ventricular mechanical support as a bridge to cardiac recovery

Objective: To study the achievability of device weaning in patients receiving left ventricular assist devices (LVADs) as a bridge to transplantation. Methods: Eighteen consecutive patients receiving a LVAD between September 1997 and June 2002 were included in the study. During a four-month follow-up, patients were repeatedly evaluated with right heart catheterization and echocardiography and, if f

Gene organization and primary structure of human hormone-sensitive lipase: possible significance of a sequence homology with a lipase of Moraxella TA144, an antarctic bacterium

The human hormone-sensitive lipase (HSL) gene encodes a 786-aa polypeptide (85.5 kDa). It is composed of nine exons spanning approximately 11 kb, with exons 2-5 clustered in a 1.1-kb region. The putative catalytic site (Ser423) and a possible lipid-binding region in the C-terminal part are encoded by exons 6 and 9, respectively. Exon 8 encodes the phosphorylation site (Ser551) that controls cAMP-m

A study on the use of empirical models to predict the formation of acrylamide in potato crisps

The formation of acrylamide in potato crisps was fitted by empirical mathematical models. Potato slices were fried under the same experimental conditions for different times. Besides the content of precursors in the raw potato slices, acrylamide and water content in the potato crisps were quantified after predetermined times (2-6 min). The temperature developments in the surrounding oil and outer

Evaluation of PIT-tagging in cyprinids.

Laboratory and field experiments were used to investigate how different marking procedures, with 23 mm PIT (passive integrated transponders) – tags, affected mortality, body condition and tag expulsion in small roach Rutilus rutilus and rudd Scardinus erythrophthalmus (117 to 163 mm total length). In a laboratory experiment mortality was low (≤ 6%) and only occurred among fishes that had their inc

Menstrual cycle characteristics in European and Inuit women exposed to persistent organochlorine pollutants

BACKGROUND Previous inconsistent results suggest that menstrual cycles may be disturbed by exposure to polychlorinated biphenyls (PCBs) and 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (DDE). METHODS Information on menstrual cycle characteristics were obtained by questionnaires, and PCB and DDE were measured in serum samples from a total of 1494 women from Greenland, Swedish fishermen's wives, a

Barley bread containing lactic acid improves glucose tolerance at a subsequent meal in healthy men and women.

In the present study, we evaluated whether a low glycemic index (GI) breakfast with lactic acid bread had an effect on glucose tolerance and insulinemia at a subsequent high GI lunch meal. A barley bread containing lactic acid and a reference barley bread were consumed in the morning after an overnight fast in random order by 10 healthy men and women. Four hours after the breakfasts, the subjects