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BACKGROUND: Breast-conserving surgery followed by radiotherapy is part of standard treatment for early-stage breast cancer. Hypoxia is common in cancer and may affect the benefit of radiotherapy. Cells adapt to hypoxic stress largely via the transcriptional activity of hypoxia-inducible factor (HIF)-1α. Here, we aim to determine whether tumour HIF-1α-positivity and hypoxic gene-expression signatur

Lymphocytes from various lymphoid organs of WF and BN rats were isolated and stained for acid alpha-naphthyl acetate esterase (ANAE) activity. From all organs examined-peripheral blood, lymph nodes, and spleen-70-80% of the lymphocytes were stained for ANAE activity. After separation into B and non-B cells by affinity chromatography on anti-Ig columns, esterase-negative lymphocytes were detected i

The ability of lymphocytes from the peripheral blood of preterm and term infants and adult women and men to mediate natural killing (NK) and K cell activity (antibody-dependent cellular cytotoxicity) was analysed in 4 hours 51Cr-release assays. K 562 cells were targets for NK activity. K cell activity was assayed on antibody-coated rat thymocytes. Lymphocytes from adult male donors were significan

The interplay between innovation and measurement has fascinated scholars from several disciplines over the last decade. All these diverse contributions, however, have resulted in a current state of knowledge that is signified by large numbers of articles without clear integration and synthesis. Therefore the aim of this explorative study is to examine the theoretical notions of innovation and meas

In this work we present a setup for laser-induced breakdown spectroscopy (LIBS) employing a polarization filtering approach and use it for gas diagnostics. A one parts-per-million (ppm) detection sensitivity is achieved for hydrogen atoms.

We utilize laser-induced breakdown spectroscopy for measuring mixture composition and temperature in flames. Spectroscopy of the plasma emission yields concentration information, while temperature is derived from the breakdown threshold pulse energy.

In this paper innovation and performance measurement are explored empirically by means of a survey. This paper studies how management accountant practitioners perceive innovation, how important they regard innovation measurement is and the specific metrics they use to assess innovation. The findings show that although innovation measurement is seen as important to practitioners, the current manage

Hydrogen peroxide (H2O2) is for the first time measured and imaged in two-dimensions in an HCCI engine using photofragmentation laser-induced fluorescence (PF-LIF). Qualitatively, the experimental data agree with simulations.

Laser-induced breakdown spectroscopy (LIBS) is an experimentally simple method capable of measuring elemental composition in a flame. Moreover, the breakdown threshold energy is temperature dependent. Hence, LIBS allows multiple parameter determination in combustion environments.

We present a calibration free technique for spatially resolved imaging of flame temperature. Its application is demonstrated in a low pressure premixed methane flame seeded with indium. Temperature measurements over a range of equivalence ratios are investigated.

This paper report on experiments performed using a dielectric barrier surface discharge to increase the combustion rate in a Bunsen-type burner. The burner has a coaxial geometry where premixed fuel-air flows in the outer annular tube while a jet of air can be injected through the central tube, thus increasing turbulent mixing and flame speed. When the central jet is used the power density but not

With a national prevalence of 4.9% in the adult population, the HIV-1 epidemic in Kenya is the fifth largest in the world. HIV-1 prevalence is more than three-fold higher among HIV key populations – including men who have sex with men (MSM), people who inject drugs (PWID), and female sex workers (FSW) than in the general heterosexual (HET) population. However, the contribution of different risk gr

Sentences with quantified expressions involve mental representations of sets of individuals for which some property holds (the reference set), as well as of sets for which the property does not hold (the complement set). Both sets can receive discourse focus with negative quantifiers, while the reference set is strongly preferred with positive quantifiers, complement set focus however being possib

Background: Upright birth positions may reduce the risk for instrumental delivery. The aim of this study was to test, by means of a randomised controlled trial, the hypothesis that the use of a birthing seat during the second stage of labour decreases the number of instrumental deliveries and thus counterbalance any adverse perineal outcome or severe blood loss.Methods: One-thousand and two nullip

How do political parties respond to external shocks? Using an original survey of political parties across Europe conducted in June 2020 and Chapel Hill Expert Survey (CHES) data on partisan ideological positioning, we argue that the pre-existing ideological stances of Europe’s political parties shaped their response to emerging Covid- 19 policy issues, including the tension between economic normal

Det finns inte fler än ungefär femton fräkenväxter i hela världen. Men under karbon- och permtiden för ungefär 300 miljoner år sedan var de mycket vanliga, och mycket större.

Background: The WHO advises against recumbent position for longer periods during labour and birth. It has been suggested that upright posi-tions may improve childbirth outcomes and reduce the need for oxytocin augmentation. However RCTs of interventions to encourage upright positions are scarce. The aims of this study were to assess whether there is a relationship between the use of oxytocin augme

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The question whether a single extreme climate event, such as a hurricane or heatwave, can be attributed to human induced climate change has become a vibrant field of research and discussion in recent years. Proponents of the most common approach (probabilistic event attribution) argue for using single event attribution for advancing climate policy, not least in the context of loss and damages, whiThe question whether a single extreme climate event, such as a hurricane or heatwave, can be attributed to human induced climate change has become a vibrant field of research and discussion in recent years. Proponents of the most common approach (probabilistic event attribution) argue for using single event attribution for advancing climate policy, not least in the context of loss and damages, whi

This paper explores whether Ethiopia's rapid economic growth is transformative enough for the country to eventually catch up with high-income countries. It does so by exploring the change and continuity of four elements of social capability from 1950 to 2020: structural transformation, economic inclusion and the state's autonomy and accountability. It finds that Ethiopia's social capability modestThis paper explores whether Ethiopia's rapid economic growth is transformative enough for the country to eventually catch up with high-income countries. It does so by exploring the change and continuity of four elements of social capability from 1950 to 2020: structural transformation, economic inclusion and the state's autonomy and accountability. It finds that Ethiopia's social capability modest