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Carbonic anhydrase (CA) is a thoroughly studied enzyme. Its primary role is the rapid interconversion of carbon dioxide and bicarbonate in the cells, where carbon dioxide is produced, and in the lungs, where it is released from the blood. At the same time, it regulates pH homeostasis. The inhibitory function of sulfonamides on CA was discovered some 80 years ago. There are numerous physiological-t
A novel DCV-system controls the air-change rate for each apartment in multifamily buildings based on two indoor air parameters: 1) the moisture load (supply), and 2) volatile organic compounds. With a central fan, but decentralized control boxes placed outside each apartment, the system controls the air-change rate for each apartment. This paper’s main aim is to determine the potential of this DCV
Unusual amongst dung beetles, Scarabaeus galenus digs a burrow that it provisions by making repeated trips to a nearby dung pile. Even more remarkable is that these beetles return home moving backwards, with a pellet of dung between their hind legs. Here, we explore the strategy that S. galenus uses to find its way home. We find that, like many other insects, they use path integration to calculate
According to IPCC reports, global climate change is likely to be accompanied by a greater frequency, intensity, and duration of heat waves in urban areas. This is related to predicted and ongoing variation of atmospheric temperature and its association with the dynamical evolution of cities. Changes in the roughness pattern of the surface, wind intensity, soil available humidity and radiative prop
As India, a country with a complex relationship with cleanliness, modernizes rapidly, urban infrastructures are increasing even faster than the growing population. This paper explores the relationships between access to infrastructures, social mobility and resource consumption in everyday lives through the case of cleanliness in Mysore, Southern India. We draw on interviews with 28 Mysoreans about
Purpose: To investigate the longitudinal changes of the macular curvature in eyes with retinitis pigmentosa (RP) and to determine the factors associated with the changes. Methods: We reviewed the medical charts of 107 RP patients, for whom the axial length of their right eyes ranged from 21.5 to 26.0 mm and who had had been followed by spectral-domain optical coherence tomography (OCT). The OCT im
Guidelines recommend the use of transthoracic echocardiography (TTE) and clinical scores to risk stratify patients after ST-elevation myocardial infarction (STEMI). High sensitivity troponin T (hs-cTnT) is predictive of outcome after STEMI but the predictive value of hs-cTnT relative to other risk assessment tools has not been established. We aimed to compare the predictive value of hs-cTnT to oth
Hybridization in bryophytes involves a fusion of gametes produced by haploid parental gametophytes of different species. The primary hybrid is thus the short-lived diploid sporophyte, which soon undergoes meiosis prior to the formation of large amounts of haploid spores. We compared morphology of gametophytes (branch leaves) and sporophytes (capsule inclination) from sympatric populations and allo
Background: International multicentre outcome studies of surgery for primary hyperparathyroidism (pHPT), especially for rate of conversion to bilateral neck surgery and persistent hypercalcaemia, are scarce. Methods: Eurocrine® is a European database for endocrine surgery. Data are entered according to predefined data fields. Outcomes for patients who underwent first surgery for sporadic pHPT were
Two-photon excitation laser induced fluorescence (2p-LIF) is used here for imaging through an optically dense spray system. The main advantage of the approach is that a low level of unwanted fluorescence signal originating from multiple-light scattering is generated. This leads to high visibility and image contrast even through scattering media, thus providing faithful descriptions of the imaged f
Grass pollen is the world’s most harmful outdoor aeroallergen. However, it is unknown how airborne pollen assemblages change across time and space. Human sensitivity varies between different species of grass that flower at different times, but it is not known whether temporal turnover in species composition match terrestrial flowering or whether species richness steadily accumulates over the grass
8 poems by Scottish poet Kathleen Jamie (b. 1962) in translation from English of Lars Gustaf Andersson, with a brief commentary.
The growth of building energy simulation tools has provided users with a variety of alternatives to model and simulate buildings. The algorithms used in each building energy simulation software are different and range from simple to highly complex. TEKNOsim is a simple design tool based on analytical and empirical algorithms. It is used for calculating building thermal loads and simulating indoor
The evolution of the traditional nuclear magic numbers away from the valley of stability is an active field of research. Experimental efforts focus on providing key spectroscopic information that will shed light into the structure of exotic nuclei and understanding the driving mechanism behind the shell evolution. In this work, we investigate the Z=6 spin-orbit shell gap towards the neutron dripli
Osteoarthritis of the carpometacarpal joint at the base of the thumb (CMC1 OA) is common and causes difficulty in grasp, grip, and fine manipulation of the hand. Surgery is recommended after failure of non-operative treatment, andevidence from short and medium-term follow-up studies shows successful relief of pain and return of function. Previous investigations of epidemiology and risk factors wer
Although some characteristics of incorporating verbs and non-incorporating verbs have been proposed in previous studies, little systematic cross-linguistic research has been done on restrictions on the types of verbs that incorporate nouns. Knowledge about possible verb-based restrictions on noun incorporation may, however, provide important insights for theoretical approaches to noun incorporatio
