Neutrophils are commonly regarded as the first line of immune response during infection or in tissue injury-induced inflammation. The rapid influx of these cells results in the release of host defense proteins (HDPs) or formation of neutrophil extracellular traps (NETs). As a second wave during inflammation or infection, circulating monocytes arrive at the site. Earlier studies showed that HDPs LL

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The objective of this study was to review and describe the current state of Swedish osteoporosis care and to highlight ongoing challenges. This report encompasses quantitative health outcomes based on Swedish registry data as well as organizational and management aspects. Swedish osteoporosis care is characterized by a significant burden of disease, difficulties in identifying high-risk patients,

In many clinical cases a dentist may feel certain when for example diagnosing, deciding on treatment, or assessing the prognosis—in other cases many dentists may feel a degree of doubt or uncertainty. This paper aims to explore the philosophical concept of uncertainty and its different dimensions, using the condition “persistent apical periodontitis associated with a previously root filled tooth”

The skeletal responses to calcium depletion and repletion in rodents have been well characterized, but those in humans are poorly understood. The present study sought to evaluate the effects of short term dietary calcium depletion and repletion on biochemical markers of bone turnover in 15 young Caucasian women (age, 21-30 yr). The study contained 3 phases: 1) 5 days of a regular diet containing m

Objective: To evaluate the influence of implant and prosthetic components on peri-implant tissue health. A further aim was to evaluate peri-implant soft-tissue changes following surgical peri-implantitis treatment. Materials and methods: Group discussions based on two systematic reviews (SR) and one critical review (CR) addressed (i) the influence of implant material and surface characteristics on

Miljövård är en i raden av verksamheter som sett det värde-fulla i att grunda beslut på en bas av systematiskt behand-lad evidens. Inspiration och egentligen hela upplägget tas från medicinen: evidensbaserad medicin (EBM). Genom EBMs fantastiska genomslag har det skapats en infra-struktur för medicinsk evidens som andra verksamheter bara kan avundas. Det har också cementerat en syn på evidens som

PURPOSE: To investigate Swedish immigrants to the United States debarred for medical reasons, with particular focus on trachoma. METHOD: Annual official reports of debarred immigrants have been compiled to compare reasons for debarment among Scandinavian immigrants vs. immigrants from all countries. Individual cases of trachoma among Swedish immigrants have been searched for in contemporary newspa

Background: The global prevalence of chronic obstructive pulmonary disease (COPD) has increased markedly in recent decades. Given the scarcity of resources available to address global health challenges and respiratory medicine being relatively under-invested in, it is important to define research priorities for COPD globally. In this paper, we aim to identify a ranked set of COPD research prioriti

AbstractGiant Cell Arteritis (GCA) is the most common vasculitis in adults among people in the western world. The pathogenesis and etiology are not fully understood.In Study I, we investigated potential predictors for developing GCA, i.e. Body Mass Index (BMI), smoking and hormone-related factors, in a nested case control study. We identified cases and matched controls (4/case) who previously had

This paper reports results from a classroom dictator game comparing the effects of three different sets of standard instructions. The results show that seemingly small and typically unreported differences in standard instructions induce different perceptions regarding entitlement and ownership of the money to be distributed, and that these perceptions influence behaviour. Less is given when the ta

Purpose: Long-term follow-up (LTFU) care is essential to optimise health outcomes in childhood cancer survivors (CCS). We aimed to assess the impact of the COVID-19 pandemic on LTFU services and providers. Methods: A COVID-19 working group within the International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG) distributed a questionnaire to LTFU service providers in 37 count

Background: Metronome cueing has been shown to reduce gait variability and thereby potentially reduce falls risk in individuals with Parkinson’s disease. It is unclear however, if metronome cueing has a similar effect in healthy older adults with a history of falls. Aim: To investigate whether a traditional and/or an adaptive metronome, based on an individual’s gait pattern, were effective in redu

Background: The continuous global rise of end-stage kidney disease creates a growing demand of economically beneficial home-based kidney replacement therapies such as peritoneal dialysis (PD). However, undesirable absorption and exposure of peritoneal tissues to glucose remain major limitations of PD. Methods: We compared a reference (standard) automated PD regimen 6 × 2 L 1.36% glucose (76 mmol/L

The mobility of workers from multinational enterprises (MNEs) to other local firms is increasingly recognized as an important externality mechanism. However, MNEs have strong incentives to curb this mobility to prevent leakage of firm-specific assets. This research note investigates the likelihood and nature of such mobility patterns. Using longitudinal, matched employer–employee data for Sweden w

GaSb is considered as an attractive p-type channel material for future III-V metal-oxide-semiconductor (MOS) technologies, but the processing conditions to utilize the full device potential such as low power logic applications and RF applications still need attention. In this work, applying rapid thermal annealing (RTA) to nanoscale GaSb vertical nanowire p-type MOS field-effect transistors, we ha

Background: Accumulating evidence suggests that statins have a beneficial effect on breast cancer prognosis. Previous studies have reported a positive association between statin use and breast cancer survival; however, the relationship between statin use and patterns of breast cancer recurrence remains unclear. Patients and methods: We identified all Malmö Diet and Cancer Study (MDCS) participants