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What makes a business model successful? In this book the roots of business models are traced to the concept of the “business idea” which was popularized by researchers in the 1960s and 1970s. The business idea stresses the importance of conformance between the market and the product system, as well as between the product system and the internal features of the firm.A distinguishing feature of the

This article poses the question of how storytelling takes place in free guided tours. It aims to explore guides’ contributions to the glocalization of urban places. Theoretically, the study departs from the concepts of glocalization, place, and storytelling. Empirically, it builds on data from Copenhagen, Berlin, Warsaw and Tallinn, collected by means of participant observations and document studi

Purpose: From the background of the dramatic increase of urban tourism, framed by the concept of overtourism, the purpose of this paper is to analyze and discuss current dynamic processes of urban tourism growth, as presented in the scientific literature. With the help of a literature review, this paper aims to discuss current definitions and conceptualizations of overtourism and discuss the drivi

A measurement of W± boson production in Pb+Pb collisions at sNN=5.02Te is reported using data recorded by the ATLAS experiment at the LHC in 2015, corresponding to a total integrated luminosity of 0.49nb-1. The W± bosons are reconstructed in the electron or muon leptonic decay channels. Production yields of leptonically decaying W± bosons, normalised by the total number of minimum-bias events and

The production cross-sections for W± and Z bosons are measured using ATLAS data corresponding to an integrated luminosity of 4.0 pb- 1 collected at a centre-of-mass energy s=2.76 TeV. The decay channels W→ ℓν and Z→ ℓℓ are used, where ℓ can be an electron or a muon. The cross-sections are presented for a fiducial region defined by the detector acceptance and are also extrapolated to the full phase

We present calculations for attosecond atomic delays in the photoionization of noble-gas atoms based on the full two-color two-photon random-phase approximation with exchange in both the length and velocity gauge. Gauge-invariant atomic delays are demonstrated for the complete set of diagrams. The results are used to investigate the validity of the common assumption that the measured atomic delays

Interaction of Streptococcus pneumoniae with the surface of endothelial cells is mediated in blood flow via mechanosensitive proteins such as the Von Willebrand Factor (VWF). This glycoprotein changes its molecular conformation in response to shear stress, thereby exposing binding sites for a broad spectrum of host-ligand interactions. In general, culturing of primary endothelial cells under a def

Standards on product information can facilitate the diffusion of innovations. This paper explores the standards related to the ventilation products with improved acoustic performance and the stakeholders involved. We introduce a new approach to classification and identification of the functions of standards in supporting such innovations. Moreover, our analysis of stakeholders indicates that the c

Mesenchymal stromal (stem) cells (MSCs) are increasingly demonstrated to ameliorate experimentally-induced lung injuries through disease-specific anti-inflammatory actions, thus suggesting that different in vivo inflammatory environments can influence MSC actions. To determine the effects of different representative inflammatory lung conditions, human bone marrow-derived MSCs (hMSCs) were exposed

The momentum measurement capability of the ATLAS muon spectrometer relies fundamentally on the intrinsic single-hit spatial resolution of the monitored drift tube precision tracking chambers. Optimal resolution is achieved with a dedicated calibration program that addresses the specific operating conditions of the 354 000 high-pressure drift tubes in the spectrometer. The calibrations consist of a

This study aims to investigate the cooling performance of various film cooling holes, including combined hole, cylinder hole, conical hole, and fan-shaped hole. For film cooling technology, a novel combined hole configuration is first proposed to improve the cooling protection for gas turbine engines. This combined hole consists of a central cylinder hole (an inclination angle of 35°) and two addi

Positioning is an essential feature in Narrow-Band Internet-of-Things (NB-IoT) systems. Observed Time Difference of Arrival is one of the supported positioning techniques for NB-IoT. It utilizes the downlink NB positioning reference signal (NPRS) generated based on a length-31 Gold sequence. Although a Gold sequence has good auto-correlation and cross-correlation properties, the correlation proper

We consider time-of-arrival (ToA) estimation for a device working in narrowband Internet-of-Things (NB-IoT) systems. Due to a limited 180 kHz bandwidth, the time-domain auto-correlation function (ACF) of transmitted NB positioning reference signal (NPRS) has a wide main-lobe. Without considering that, the performance of ToA estimation can be degraded for two reasons. Firstly, the NPRS correspondin

We propose an improvement over a modulus zero-forcing (MZF) detector proposed earlier in [1] for multi-input multi-output (MIMO) detection, namely, the joint MZF (JMZF) detector. The MZF detector provides better detection-performance than a traditional ZF detector through preserving controllable interferences, which are mitigated later by nonlinear modulus arithmetic operation. However, the MZF de

We consider Boolean circuits over {∨, ∧, ¬} with negations applied only to input variables. To measure the “amount of negation” in such circuits, we introduce the concept of their “negation width.” In particular, a circuit computing a monotone Boolean function f(x1, . . ., xn) has negation width w if no nonzero term produced (purely syntactically) by the circuit contains more than w distinct negat

Aims: Few studies have examined how improved metabolic control might influence vibration perception thresholds (VPTs). The aim of this study was to evaluate if improved HbA1c can influence vibration thresholds in adults with type 1 diabetes (T1DM). Methods: VPTs were investigated at six frequencies (4–125 Hz) using VibroSense Meter in the sole of the foot at two occasions in 159 T1DM patients, at

Previous open-label trials testing glial cell line-derived neurotrophic factor (GDNF) family ligands in Parkinson disease have shown promising clinical effects. However, in placebo-controlled trials, the treatments have failed. A new randomized placebo-controlled trial of intraputamenal delivery of GDNF designed to resolve this conundrum has again failed to do just that.

Accumulating data suggest that neutrophil extracellular traps (NETs) exert a key function in several diseases. Peptidylarginine deiminase 4 (PAD4) regulates NET formation via citrullination of histones. The aim of this study was to examine the role of miR-155 in controlling PAD4-dependent generation of NETs. Bone marrow neutrophils were stimulated with PMA and MIP-2. Pre-incubation of neutrophils

Genomgång av existerande dokumentation i Lunds universitetsarkiv rörande folkbildaren och riksdagsmannen Oscar Olssons studietid 1897-1902 med särskilt fokus på Hans Larssons undervisning under denna period.