Experimental autoimmune encephalomyelitis (EAE) shares similar immunological and clinical features with multiple sclerosis (MS), and is therefore widely used as a model to identify new drug targets for better patient treatment. MS is characterized by several different disease courses: relapsing-remitting MS (RRMS), primary progressive MS (PPMS), secondary progressive MS (SPMS), and a rare progress

An efficient immune system is essential to the survival of many animals. Sociality increases risk of pathogen transmission, which should select for enhanced immune function. However, two hypotheses instead predict a weakened immune function: relaxed selection caused by social immunity/protection, and reduced efficacy of selection due to inbreeding, reproductive skew and female bias in social speci

Background: In the past decades, the incidence of obesity has increased worldwide. This disease is often accompanied with several comorbidities and therefore, surgeons and anesthesiologists should be prepared to provide optimal management for these patients. The aim of this descriptive cross-sectional study was to map the criteria and routines that are used by Swedish knee arthroplasty surgeons to

En betydande del av näringslivet och civilsamhället bedrivs av och i olika slags associationer. Associationsrätt handlar om de regler som möjliggör och styr verksamheten i associationerna. Associationsrättens grunder ger en systematisk överblick över rättsområdet och dess centrala problem. Fokus ligger på allmänna bolags- och föreningsformer, men boken redogör även för regleringen av stiftelser. I

Investigating how publics form, this study aims to develop an understanding of how publics of Sweden’s feminist foreign policy are constructed in public diplomacy discourse. To this end, the study conceptualizes publics as forming around perceptions of foreign policy that are mediated through public diplomacy events. Based on a debate on Sweden’s feminist foreign policy on the digital platform Red

The tenth-century Byzantine hagiographical Life of Theoktiste, written by Niketas Magistros, has been read in various ways, not in the least intertextually and as the life of a non-existing saint. The present article further investigates the motives of the author, the social and cultural vision, as well as generic notions, embedded in the text, and offers a new date of composition for the Life, vi

Nearly 60% of the worlds adult population is projected to be overweight or obese by 2030. The prevalence of obesity- related diseases, such as type 2 diabetes (T2D), has increased markedly in the past decades. The adipose tissue plays an important role in disease progression of T2D. Adipocyte insulin sensitivity, adipose tissue’s ability to expand, and accumulation of subcutaneous rather than visc

Background: Most antidepressant treatment studies have included patients strictly based on the Diagnostic and Statistical Manual of Mental Disorders definition of Major Depressive Disorder (MDD). Given the heterogeneity of MDD, this approach may have obscured inter-patient differences and hampered the development of novel and targeted treatment strategies. An alternative strategy is ​​to use bioma

In this paper, we present an extension of MadGraph5_aMC@NLO which is able to evaluate tree-level QCD matrix-elements up to 2 → 6 (one more particle than before). To achieve this, we implemented Berends–Giele-like recursion, and re-implemented the way colour is computed such that we can now expand the colour matrix in powers of 1 / Nc and truncate this expansion to a chosen order. For high multipli

Wood is a remarkable material with great cultural, economic, and biogeochemical importance. However, our understanding of its formation is poor. Key properties that have not been explained include the anatomy of growth rings (with consistent transitions from low-density earlywood to high density latewood), strong temperature-dependence of latewood density (used for historical temperature reconstru