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Introduction: Using a sum score based on a three-graded response scale for the activities of daily living staircase has previously been found to increase the statistical power compared to dichotomized responses when assessing longitudinal changes in activities of daily living. We aimed to investigate if the statistical power could be further increased by using a four-graded scale. Methods: We used

Galectins are a family of carbohydrate recognition proteins involved in, among other things, modulating cell signalling and cell-environment interactions, giving them roles in several pathologies like cancer and idiopathic lung fibrosis. Hence, developing new galectin inhibitors with high affinity and high selectivity is important to be able to target such diseases. Most existing galectin inhibito

Objective: To test the hypothesis that a combination of 6 posterior and 6 anterior cores detects more cancer than 12 posterior cores at a repeat transrectal prostate biopsy in men who have had one previous benign systematic biopsy. Patients and methods: Three hundred and forty men with persistently raised serum PSA were randomly allocated 1:1 to either a standard 12-core biopsy (12 cores from the

The tensile and compressive properties of acrylic bone cement containing iohexol acetate (IHA) were investigated. The IHA monomer was prepared with 4 g of IHA dissolved in 20 ml of palacos monomer, later mixed with 36 g of palacos powder. The ultimate tensile strength (UTS) and ultimate tensile strain of IHA cement was compared with Palacos R. The IHA cement show significantly higher UTS and ultim

It is reasonable to consider that those who arranged the material accoutrements of mortuary practices, i.e. the burial, were making a more or less conscious statement about cultural identity. At least we archaeologists usually assume this to be so. An interesting case can be found in the mortuary practices ascribed to the Battle Axe culture from the later Middle Neolithic1 (2800–2350 cal BC) in so

Popular Abstract in Swedish Hjärtsvikt är ett sjukdomstillstånd som blir allt vanligare i vårt samhälle i takt med att människor blir äldre och att man idag räddar allt fler människor till livet efter hjärtinfarkt. Som namnet antyder sviktar hjärtat, det kan inte pumpa ut den mängd blod som krävs för att tillgodose kroppens behov av syre och näringsämnen. Sjukdomen indelas i olika svårighetsgraderCongestive heart failure is accompanied with increased circulatory levels of several vasoregulatory neurotransmitters and hormones which affect the outcome of this disease. In this thesis the blood levels of several vasoactive peptides in humans with congestive heart failure and their effects on the vasculature by the use of an animal model of heart failure were studied. Patients with congestive

Abstract not available

Due to the increasing power requirement and the limited available space in vehicles, placing the heat exchanger at the roof or the underbody of vehicles might increase the possibility to handle the cooling requirement. A new configuration of the heat exchanger has to be developed to accommodate with the position change. In this paper, a countercurrent heat exchanger is developed for position on th

Abstract in UndeterminedThe make-or-buy decision is analyzed in a simple framework combining contractual incompleteness with the existence of an imperfect but contractible performance measure. Contractual incompleteness gives rise to two regimes, identified with make and buy. The performance measure on which comprehensive contracts can be written is imperfect in the sense of being subject to manip

Lattice Boltzmann method (LBM) is alternative computational method to the traditional computational fluid dynamic (CFD) methods. LBM has the ability to with straightforward computational procedure to handle the detail activity at microscale well for simulation of different transport processes. In this study the focus is on the effects of electrochemical reactions and transport processes in an anod

Looking beyond the current debate’s preoccupation with the situations of insecurity of the second intifada and 9/11, this book reveals how targeted killing is intimately embedded in both Israeli and US statecraft and in the problematic relation of sovereign authority and lawful violence underpinning the modern state system. The book details the legal and political issues raised in targeted killing