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We determined the risk of late morbidity and mortality after autologous blood or marrow transplantation (BMT) for lymphoma performed before age 40. The cohort included autologous BMT recipients who had survived ≥2 years after transplantation (N = 583 [HL = 59.9%; NHL = 40.1%]) and a comparison cohort (N = 1070). Participants self-reported sociodemographics and chronic health conditions. A severity

CONTEXT: Agriculture plays a central role as a feedstock provider for the bioeconomy. However, utilization competing with food production and associated land use change have previously been a matter of debate. Nonetheless, strengthening the productivity of agroecosystems through sustainable intensification can prevent the depletion of natural resources, enhance food security, and facilitate adapta

The exceptional polymorphism observed within genes of the major histocompatibility complex (MHC), a core component of the vertebrate immune system, has long fascinated biologists. The highly polymorphic classical MHC class-I (MHC-I) genes are maintained by pathogen-mediated balancing selection (PMBS), as shown by many sites subject to positive selection, while the more monomorphic non-classical MH

As tech giants such as Apple and Meta invest heavily in Virtual and Augmented Reality (VR/AR) technologies, often collectively termed Extended Reality (XR) devices, a significant societal concern emerges: The use of eye-tracking technology within these devices. Gaze data holds immense value, revealing insights into user attention, health, and cognitive states. This raises substantial concerns over

In atopic dermatitis (AD), Staphylococcus aureus fre-quently colonizes lesions, leading to superinfections that can then lead to exacerbations. The presence of biofilm-producing isolates has been associated with worsening of the disease. Potassium permanganate is used as a topical treatment of infected eczema, bliste-ring conditions, and wounds. Little is known of its effects against microbes in A

We study quantum steering experiments without assuming that the trusted party can perfectly control their measurement device. Instead, we introduce a scenario in which these measurements are subject to small imprecision. We show that small measurement imprecision can have a large detrimental influence in terms of false positives for steering inequalities, and that this effect can become even more

Haemoproteus blood parasites of birds are thought to be relatively benign. Recent findings show that infections may develop in the brain of birds, possibly distorting their orientation sense. Misdirected migration may lead migrants outside their range where they are recognized as vagrants and can transmit parasites to novel hosts.

Nitrogenase is the only enzyme that can cleave the triple bond in N2, making nitrogen available to organisms. The detailed mechanism of this enzyme is currently not known, and computational studies are complicated by the fact that different density functional theory (DFT) methods give very different energetic results for calculations involving nitrogenase models. Recently, we designed a [Fe(SH)4H]

Four-wave mixing techniques, such as coherent anti-Stokes Raman spectroscopy (CARS), laser-induced grating spectroscopy (LIGS), and degenerate four-wave mixing (DFWM), have been widely used in combustion diagnostics due to their advantages of high signal-to-noise ratio (S/N), coherent signal, and spatial resolution. In this work, a nano-second pulsed laser is utilized to generate mid-infrared (nea

Boken innehåller aktuella lagändringar och domstolsbeslut för att enkelt se att medborgaren får rätt stöd. Den klara och begripliga framställningen rätar snabbt ut de flesta frågetecknen kring lagens innehåll och tillämpning.

Particle sintering and reshaping constitute the main cause for catalyst deactivation. An atomic-scale understanding of the correlation among the catalyst structure, its support, and the gas phase under realistic reaction conditions is required for its suppression. In this study, we combined high-energy grazing incidence X-ray diffraction, in situ mass spectrometry, ex situ scanning electron micros

Objectives To investigate the relation between patient characteristics at rheumatoid arthritis (RA) diagnosis and subsequent initiation of treatment with biologic disease-modifying antirheumatic drugs (bDMARDs) or targeted synthetic DMARDs (tsDMARDs). Design A retrospective cohort study. Setting and participants Consecutive patients (N=330) with early RA (symptom duration <12 months) diagnosed at

Background: Illegal drug use is a public health concern with far-reaching consequences for people who use them and for society. In Sweden, the reported use of illegal drugs has been growing and the number of drug-induced deaths is among the highest in Europe. The aim of this study was to provide a comprehensive and up-to-date estimation of the societal costs of illegal drug use in Sweden, relying

Despite various preventive interventions, nosocomial cross-infection remains a significant challenge in healthcare facilities worldwide. Consequently, prolonged hospitalization, elevated healthcare costs, and mortality rates are major concerns. Proper ventilation has been identified as one of the possible interventions for reducing the risk of cross-infection between patients and healthcare worker

We consider the set Rio of points returning infinitely many times to a sequence of shrinking targets around themselves. Under additional assumptions we improve Boshernitzan’s pioneering result on the speed of recurrence. In the case of the doubling map as well as for some linear maps on the d-dimensional torus, we even obtain a dichotomy condition for Rio to have measure-zero or one. Moreover, we

BACKGROUND: Identifying variables predictive of acute myocardial infarction (AMI) in women is important. The use of the ratio of total cholesterol-to-high density lipoprotein cholesterol (TC/HDL-C) is often overlooked. The aim was to study TC/HDL-C in relation to later AMI, in a large sample of women, adjusted for age, educational status, smoking, waist-hip ratio, blood pressure, and neighbourhood

Aim: The sweeping transformation of the biosphere by humans over the last millennia leaves only limited windows into its natural state. Much of the forests that dominated temperate and southern boreal regions have been lost and those that remain typically bear a strong imprint of forestry activities and past land-use change, which have changed forest age structure and composition. Here, we ask how